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  • Open Access

    REVIEW

    Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

    KARAN WADHWA1, PAYAL CHAUHAN1, SHOBHIT KUMAR2, RAKESH PAHWA3,*, RAVINDER VERMA4, RAJAT GOYAL5, GOVIND SINGH1, ARCHANA SHARMA6, NEHA RAO3, DEEPAK KAUSHIK1,*

    Oncology Research, Vol.32, No.5, pp. 877-897, 2024, DOI:10.32604/or.2024.047278

    Abstract Background: Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective: Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods: Relevant literature for this manuscript has been collected from a comprehensive and systematic search of… More > Graphic Abstract

    Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

  • Open Access

    ARTICLE

    Unsteady MHD Casson Nanofluid Flow Past an Exponentially Accelerated Vertical Plate: An Analytical Strategy

    T. Aghalya, R. Tamizharasi*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 431-460, 2024, DOI:10.32604/cmes.2024.046635

    Abstract In this study, the characteristics of heat transfer on an unsteady magnetohydrodynamic (MHD) Casson nanofluid over an exponentially accelerated vertical porous plate with rotating effects were investigated. The flow was driven by the combined effects of the magnetic field, heat radiation, heat source/sink and chemical reaction. Copper oxide () and titanium oxide () are acknowledged as nanoparticle materials. The nondimensional governing equations were subjected to the Laplace transformation technique to derive closed-form solutions. Graphical representations are provided to analyze how changes in physical parameters, such as the magnetic field, heat radiation, heat source/sink and chemical reaction, affect the velocity, temperature… More >

  • Open Access

    ARTICLE

    Unraveling the Rheology of Nanocellulose Aqueous Suspensions: A Comprehensive Study on Biomass-Derived Nanofibrillated Cellulose

    Mingyue Miao1,#, Fei Wang1,#, Qing Li1, Longchen Tao1, Chenchen Dai1, Yu Liu1, Shujuan Han1, Wenshuai Chen1,*, Ping Lu2,*

    Journal of Renewable Materials, Vol.12, No.3, pp. 443-455, 2024, DOI:10.32604/jrm.2023.030412

    Abstract The rheological properties of nanocellulose aqueous suspensions play a critical role in the development of nanocellulose-based bulk materials. High-crystalline, high-aspect ratio, and slender nanofibrillated cellulose (NFC) were extracted from four biomass resources. The cellulose nanofibrils and nanofibril bundles formed inter-connected networks in the NFC aqueous suspensions. The storage moduli of the suspensions with different concentrations were higher than their corresponding loss moduli. As the concentration increased, the storage and loss modulus of NFC dispersion increased. When the shear rate increased to a certain value, there were differences in the changing trend of the rheological behavior of NFC aqueous suspensions derived… More > Graphic Abstract

    Unraveling the Rheology of Nanocellulose Aqueous Suspensions: A Comprehensive Study on Biomass-Derived Nanofibrillated Cellulose

  • Open Access

    ARTICLE

    Mechanical and Biological Properties of Chitosan Nanocomposite Films: Effects of POSS nanoparticles

    R. VENKATESAN*, S. R. DARSON IMMANUEL JOHN, N. RAJESWARI

    Journal of Polymer Materials, Vol.36, No.3, pp. 261-273, 2019, DOI:10.32381/JPM.2019.36.03.6

    Abstract Nanocomposite films of chitosan (CH) incorporated with different wt. % of the polyoligomericsilsesquioxane (POSS) were prepared by solution casting. The thermal, mechanical, morphological and antimicrobial properties of the nanocomposites were examined. TGA analyses of the nanocomposites indicate that the filler enables the enhancement of thermal stability of chitosan. The tensile strength of the nanocomposite films is enhanced (10.9 MPa for neat chitosan to 24.0MPa for 5wt. % filled chitosan) by the addition of POSS while the elongation at break is reduced. The nanocomposite films exhibited excellent antimicrobial activity against both gram positive and gram negative bacteria. This activity increases with… More >

  • Open Access

    ARTICLE

    VOC Sensing Studies on Electrically Conductive Polyaniline@MoS2 Nanocomposites

    RUBY AHMED1, MOHAMMAD OMAISH ANSARI2, FARMAN ALI1, SHAHID PERVEZ ANSARI1,*

    Journal of Polymer Materials, Vol.36, No.3, pp. 243-251, 2019, DOI:10.32381/JPM.2019.36.03.4

    Abstract Polyaniline (PANI) and molybdenum disulphide (MoS2 ) were used to prepare nanocomposites by in-situ oxidative polymerization of acidified aniline in presence of dispersed MoS2 in the reaction mixture. Electron Microscopy (SEM & TEM), Fourier Transform Infrared (FTIR) spectroscopy, Ultraviolet-Visible (UV-Vis) spectroscopy, and X-ray diffraction (XRD) were used to characterize these nanocomposites. SEM micrographs showed that PANI is present on the layers of MoS2 which were exfoliated during the preparation and the presence of MoS2 is also confirmed by XRD peaks. The nanocomposites were studied for their electrical conductivity and stability of electrical conductivity in terms of d.c. electrical conductivity retention.… More >

  • Open Access

    ARTICLE

    Influence of Poly (vinyl butyral) Modification on the Mechanical and Thermal Properties of Kevlar Fiber Reinforced Novolac epoxy/multiwalled carbon nanotube nanocomposites

    KAVITA*, R.K. TIWARI

    Journal of Polymer Materials, Vol.36, No.2, pp. 195-205, 2019, DOI:10.32381/JPM.2019.36.02.7

    Abstract The effect of poly (vinyl butyral) and acid functionalized multiwalled carbon nanotubes (f-MWCNT) on the thermal and mechanical performance of Kevlar fiber reinforced novolac epoxy nanocomposites was investigated and presented in this paper. Nanocomposite containing 1.5 wt. % poly (vinyl butyral) and 0.5 wt. % f-MWCNT exhibited best thermal and mechanical properties (except flexural strength) among all the nanocomposites reported here. It showed ~5%, 27% and 126 % improvement in tensile strength, young’s modulus and impact strength respectively as compared to the neat novolac epoxy Kevlar composite.Nanocomposite containing 0.5 wt. % f- MWCNT and 2 wt. % poly (vinyl butyral)… More >

  • Open Access

    REVIEW

    Recent Advancement in Comb-like Polymers: A Review

    AMRITA SHARMA, P. P. PANDE

    Journal of Polymer Materials, Vol.36, No.2, pp. 175-194, 2019, DOI:10.32381/JPM.2019.36.02.6

    Abstract ‘Comb-like polymers’ are a special class of polymers. These are consisting of two types of chains, first one is the backbone chain and second is long side chains. The structure of such a polymer is very similar to hair comb. Usually, every monomer unit in the backbone has a long n-alkyl side chain. Comb like polymers have an intrinsic ability towards forming ordered structure. Now-a-days, these polymers find wide range of applications because of their excellent physicochemical properties. Some applications are in preparation of polysoaps (polymeric disinfectants), as dispersing agent for ink and paints, textile industry, in surface modification of… More >

  • Open Access

    ARTICLE

    Covalent Immobilization of Lipase on Novel Nanofibrous Membrane for Catalysis of the Organic Synthesis

    YINCHUN FANGa, XINHUA LIUa,b,*, XU YANGa, CUIE WANGa,*

    Journal of Polymer Materials, Vol.36, No.2, pp. 111-119, 2019, DOI:10.32381/JPM.2019.36.02.1

    Abstract Enzymes are green biocatalysts which have been widely used in many fields. Immobilization enzymes on nanofibrous membrane possessed easy recycling and high stability which would broaden their applications. Covalent immobilization of lipase could endow them higher stability than other protocols. In this study, a novel nanofibrous membrane containing epoxy groups and hydrophilic polyethylene oxide branch was used as a support for lipase immobilization. The immobilized lipase was used as the biocatalyst to catalyse Rap. stroermer reaction. The results showed that it obtained the high product yield of 88% when the volume ratio of methanol and water was 4:1, the dosage… More >

  • Open Access

    ARTICLE

    Improved Corrosion Resistance of Carbon Reinforced Aluminium Laminates in Atmospheric Environment: Role of Environment Friendly Jute Fibre/ Alumina nano Coating

    M. VASUMATHI1,a,*, VELA MURALI2,b, S. RASHIA BEGUM1,c, N. RAJENDRAN2,d

    Journal of Polymer Materials, Vol.36, No.1, pp. 1-11, 2019, DOI:10.32381/JPM.2019.36.01.1

    Abstract In the Fibre Metal Laminate (FML), Carbon Reinforced Aluminium laminate (CARALL), aluminium is placed next to carbon fibres. The potential difference between the aluminium and carbon is larger, leads to galvanic corrosion, which tries to bring down the durability of the FML. To bring down the effect of corrosion, a material layer is introduced between fibres and aluminium so as to separate them thus lowering the possibility of occurrence of corrosion. Another approach is to coat the surfaces of aluminium with different proportions of aluminium oxide nano particles prior to fabrication of the FML. For both the cases, corrosion rates… More >

  • Open Access

    ARTICLE

    Performance Enhancement of Bio-fouling Resistant Cellulose triacetate-based Osmosis Membranes using Functionalized Multiwalled Carbon Nanotube & Graphene Oxide

    A.K. GHOSH1, RUTUJA S. BHOJE2, R.C. BINDAL1

    Journal of Polymer Materials, Vol.37, No.1-2, pp. 109-120, 2020, DOI:10.32381/JPM.2020.37.1-2.8

    Abstract In this study, cellulose triacetate (CTA) based nanocomposite membranes were developed by incorporation of carboxylic acid functionalized multiwalled carbon-nanotube (cMWCNT) and graphene oxide (GO) which have enhancement of both flux and fouling resistance properties of the membranes. Membranes were casted at room temperature and annealed at 90o C hot water for 10 minutes. The incorporation level of both the nanomaterials is 1.5% of the CTA polymer weight in the nanocomposite membranes. Prepared membranes were characterized in terms of water contact angle, surface morphology and mechanical strength. The performance of the membranes was evaluated both in reverse osmosis (RO) and forward… More >

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