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  • Open Access

    PROCEEDINGS

    Research on the Synergistic Mechanism of Photothermal-Chemotherapy-Immunotherapy of Multi-Functional Nanoparticles Against Gastric Cancer

    Erdong Shen1, Ting Pan1, Pan Guo1, Ke Chen1, Rui Xu1, Mei Yang1, Dahe Zhan1, Fang Fang1, Qinghui Wu1,*, Jianbing Hu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-3, 2024, DOI:10.32604/icces.2024.012772

    Abstract Objective
    This study investigates the synergistic effects of a novel multifunctional nanoparticle on gastric cancer treatment through photothermal therapy, chemotherapy, and immunotherapy.

    Method
    Synthesize hollow mesoporous Prussian blue nanoparticles and load them with luteolin. Use exosomes to encapsulate the nanoparticles and modify the surface of the targeted peptide GX1. Detect the morphology of nanoparticles using a nanoparticle size analyzer and transmission electron microscopy. Use Coomassie Brilliant Blue to detect the effect of extracellular vesicle encapsulation. Detect the thermal conversion efficiency of nanoparticles under specific laser irradiation through infrared and ultraviolet spectroscopy, as well as the release rate… More >

  • Open Access

    REVIEW

    Impact of nanoparticles on immune cells and their potential applications in cancer immunotherapy

    JYOTHI B. NAIR1,2, ANU MARY JOSEPH3, SANOOP P.4, MANU M. JOSEPH5,*

    BIOCELL, Vol.48, No.11, pp. 1579-1602, 2024, DOI:10.32604/biocell.2024.054879 - 07 November 2024

    Abstract Nanoparticles represent a heterogeneous collection of materials, whether natural or synthetic, with dimensions aligning in the nanoscale. Because of their intense manifestation with the immune system, they can be harvested for numerous bio-medical and biotechnological advancements mainly in cancer treatment. This review article aims to scrutinize various types of nanoparticles that interact differently with immune cells like macrophages, dendritic cells, T lymphocytes, and natural killer (NK) cells. It also underscores the importance of knowing how nanoparticles influence immune cell functions, such as the production of cytokines and the presentation of antigens which are crucial for… More >

  • Open Access

    PROCEEDINGS

    Multiscale Mechanics Design of Biodegradable Nano-Architected Materials: Toward a Sustainable Future

    Yuanzhen Hou1, YinBo Zhu1, Heng-an Wu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-2, 2024, DOI:10.32604/icces.2024.011353

    Abstract Traditional materials are emerging increasingly severe problems such as environmental pollution, non-renewability, and resource waste. As the most abundant natural biomass in nature, nanocellulose materials are expected to become a new generation of green, biodegradable, high-performance structural materials and contribute to sustainable development. Starting from the intrinsic relationship between hydrogen bonding network and microstructure deformation in nanocellulose, we performs the bottom-up multiscale mechanics methods, combing theoretical modeling, experimental characterization and material preparation, to reveal the physical mechanism and key characteristic parameters of the microstructure-regulated mechanical behaviors of nanocellulose materials, further establishing the cross-scale relationship between… More >

  • Open Access

    PROCEEDINGS

    Intrinsic Deformation Mechanism of Nanocellulose

    Rongzhuang Song1, Yinbo Zhu1,*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.3, pp. 1-1, 2024, DOI:10.32604/icces.2024.012598

    Abstract Kink defects are prevalent in nanocellulose. The existence of diverse kink patterns lacking molecular-scale resolution has caused uncertainty regarding the mechanisms governing the formation of different kinks in nanocellulose, including both reversible and irreversible kinks. The constraints resulting from these limitations often lead to significant confusion in exploring the structure-property relationships of nanocellulose. By integrating AFM experiments with molecular dynamics simulations, we examined the microstructure-dependent kink deformations in nanocellulose (Iβ phase) and the resultant local microstructural damages. In atomic force microscopy images, bent nanofibrils typically display minor curvatures, whereas kinked nanofibrils exhibit pronounced sharp bends,… More >

  • Open Access

    PROCEEDINGS

    Thermal Insulating and Fire Retardant Si3N4 Nanowires Membranes Resistant to High-Temperatures up to 1300 °C

    Yeye Liu1, Leilei Zhang1,*, Ruonan Zhang1, Siqi Shao1, Lina Sun1, Xinyi Wan1, Tiantian Wang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012576

    Abstract Superior thermal insulating and fire-retardant ceramic membranes are urgently demanded in the aerospace, construction and chemical engineering industries. However, the generic characteristics of ceramic membranes, such as brittleness, structural collapse and crystallization-induced pulverization behavior, present a great plague to their practical applications. Herein, we report a highly flexible, mechanically stable, fire retardant and high-temperature-resistant ceramic membrane based on the interlocked Si3N4 nanowires formed by the precursor pyrolysis method. The Si3N4 nanowires membrane (SNM) has excellent high temperature resistance under alcohol lamp and butane spray lance. The thermal insulation with a thermal conductivity as low as 0.056… More >

  • Open Access

    PROCEEDINGS

    Fast and Accurate Calculation on Competitive Adsorption Behavior in Shale Nanopores by Machine Learning Model

    Hao Yu1,*, Mengcheng Huang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.011120

    Abstract Understanding the competitive adsorption behavior of CO2 and CH4 in shale nanopores is crucial for enhancing the recovery of shale gas and sequestration of CO2, which is determined by both the inherent characteristics of the molecules and external environmental factors such as pore size, temperature, and partial pressures of CO2 and CH4. While the competitive adsorption behavior of CO2/CH4 has been analyzed by previous studies, a comprehensive understanding from the perspective of molecular kinetic theory and the efficient calculation for competitive adsorption behavior considering various geological situations is still challenging, limited by the huge computation cost of classical… More >

  • Open Access

    ARTICLE

    Unsteady Flow of Hybrid Nanofluid with Magnetohydrodynamics- Radiation-Natural Convection Effects in a U-Shaped Wavy Porous Cavity

    Taher Armaghani1, Lioua Kolsi2, Najiyah Safwa Khashi’ie3,*, Ahmed Muhammed Rashad4, Muhammed Ahmed Mansour5, Taha Salah6, Aboulbaba Eladeb7

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.3, pp. 2225-2251, 2024, DOI:10.32604/cmes.2024.056676 - 31 October 2024

    Abstract In this paper, the unsteady magnetohydrodynamic (MHD)-radiation-natural convection of a hybrid nanofluid within a U-shaped wavy porous cavity is investigated. This problem has relevant applications in optimizing thermal management systems in electronic devices, solar energy collectors, and other industrial applications where efficient heat transfer is very important. The study is based on the application of a numerical approach using the Finite Difference Method (FDM) for the resolution of the governing equations, which incorporates the Rosseland approximation for thermal radiation and the Darcy-Brinkman-Forchheimer model for porous media. It was found that the increase of Hartmann number… More >

  • Open Access

    ARTICLE

    Melting Flow Analyzation of Radiative Riga Plate Two-Phase Nano-Fluid Across Non-Flatness Plane with Chemical Reaction

    Jupudi Lakshmi Rama Prasad1, F. Mebarek-Oudina2,*, G. Dharmaiah3, Putta Babu Rao4, H. Vaidya5

    Frontiers in Heat and Mass Transfer, Vol.22, No.5, pp. 1515-1532, 2024, DOI:10.32604/fhmt.2024.057854 - 30 October 2024

    Abstract There is a strong relationship between analytical and numerical heat transfers due to thermodynamically anticipated findings, making thermo-dynamical modeling an effective tool for estimating the ideal melting point of heat transfer. Under certain assumptions, the present study builds a mathematical model of melting heat transport nanofluid flow of chemical reactions and joule heating. Nanofluid flow is described by higher-order partial non-linear differential equations. Incorporating suitable similarity transformations and dimensionless parameters converts these controlling partial differential equations into the non-linear ordinary differential equations and resulting system of nonlinear equations is established. Plotted graphic visualizations in MATLAB More >

  • Open Access

    ARTICLE

    Nanofluid Heat Transfer in Irregular 3D Surfaces under Magnetohydrodynamics and Multi-Slip Effects

    Mumtaz Khan1,*, Muhammad Shoaib Anwar2, Mudassar Imran3, Amer Rasheed4

    Frontiers in Heat and Mass Transfer, Vol.22, No.5, pp. 1399-1419, 2024, DOI:10.32604/fhmt.2024.056597 - 30 October 2024

    Abstract This study employs the Buongiorno model to explore nanoparticle migration in a mixed convection second-grade fluid over a slendering (variable thickness) stretching sheet. The convective boundary conditions are applied to the surface. In addition, the analysis has been carried out in the presence of Joule heating, slips effects, thermal radiation, heat generation and magnetohydrodynamic. This study aimed to understand the complex dynamics of these nanofluids under various external influences. The governing model has been developed using the flow assumptions such as boundary layer approximations in terms of partial differential equations. Governing partial differential equations are… More >

  • Open Access

    ARTICLE

    A Novel Integrated Photovoltaic System with a Three-Dimensional Pulsating Heat Pipe

    Mahyar Kargaran*, Hamid Reza Goshayeshi, Ali Reza Alizadeh Jajarm

    Frontiers in Heat and Mass Transfer, Vol.22, No.5, pp. 1461-1476, 2024, DOI:10.32604/fhmt.2024.056284 - 30 October 2024

    Abstract Solar energy is a valuable renewable energy source, and photovoltaic (PV) systems are a practical approach to harnessing this energy. Nevertheless, low energy efficiency is considered a major setback of the system. Moreover, high cell temperature and reflection of solar irradiance from the panel are considered chief culprits in this regard. Employing pulsating heat pipes (PHPs) is an innovative and useful approach to improving solar panel performance. This study presents the results of the power performance of a PV panel attached to a newly designed spiral pulsating heat pipe, while graphene oxide nanofluid with three More >

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