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  • Open Access

    ARTICLE

    A Hybrid Deep Learning Multi-Class Classification Model for Alzheimer’s Disease Using Enhanced MRI Images

    Ghadah Naif Alwakid*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-25, 2026, DOI:10.32604/cmc.2025.068666 - 10 November 2025

    Abstract Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that significantly affects cognitive function, making early and accurate diagnosis essential. Traditional Deep Learning (DL)-based approaches often struggle with low-contrast MRI images, class imbalance, and suboptimal feature extraction. This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans. Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization (CLAHE) and Enhanced Super-Resolution Generative Adversarial Networks (ESRGAN). A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient (MCC)-based evaluation method into the design.… More >

  • Open Access

    ARTICLE

    Deep Architectural Classification of Dental Pathologies Using Orthopantomogram Imaging

    Arham Adnan1, Muhammad Tuaha Rizwan1, Hafiz Muhammad Attaullah1,2,*, Shakila Basheer3, Mohammad Tabrez Quasim4

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 5073-5091, 2025, DOI:10.32604/cmc.2025.068797 - 23 October 2025

    Abstract Artificial intelligence (AI), particularly deep learning algorithms utilizing convolutional neural networks, plays an increasingly pivotal role in enhancing medical image examination. It demonstrates the potential for improving diagnostic accuracy within dental care. Orthopantomograms (OPGs) are essential in dentistry; however, their manual interpretation is often inconsistent and tedious. To the best of our knowledge, this is the first comprehensive application of YOLOv5m for the simultaneous detection and classification of six distinct dental pathologies using panoramic OPG images. The model was trained and refined on a custom dataset that began with 232 panoramic radiographs and was later… More >

  • Open Access

    ARTICLE

    Enhancing Multi-Class Cyberbullying Classification with Hybrid Feature Extraction and Transformer-Based Models

    Suliman Mohamed Fati1,*, Mohammed A. Mahdi2, Mohamed A.G. Hazber2, Shahanawaj Ahamad3, Sawsan A. Saad4, Mohammed Gamal Ragab5, Mohammed Al-Shalabi2

    CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.2, pp. 2109-2131, 2025, DOI:10.32604/cmes.2025.063092 - 30 May 2025

    Abstract Cyberbullying on social media poses significant psychological risks, yet most detection systems oversimplify the task by focusing on binary classification, ignoring nuanced categories like passive-aggressive remarks or indirect slurs. To address this gap, we propose a hybrid framework combining Term Frequency-Inverse Document Frequency (TF-IDF), word-to-vector (Word2Vec), and Bidirectional Encoder Representations from Transformers (BERT) based models for multi-class cyberbullying detection. Our approach integrates TF-IDF for lexical specificity and Word2Vec for semantic relationships, fused with BERT’s contextual embeddings to capture syntactic and semantic complexities. We evaluate the framework on a publicly available dataset of 47,000 annotated social… More >

  • Open Access

    ARTICLE

    Three-Stage Transfer Learning with AlexNet50 for MRI Image Multi-Class Classification with Optimal Learning Rate

    Suganya Athisayamani1, A. Robert Singh2, Gyanendra Prasad Joshi3, Woong Cho4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.142, No.1, pp. 155-183, 2025, DOI:10.32604/cmes.2024.056129 - 17 December 2024

    Abstract In radiology, magnetic resonance imaging (MRI) is an essential diagnostic tool that provides detailed images of a patient’s anatomical and physiological structures. MRI is particularly effective for detecting soft tissue anomalies. Traditionally, radiologists manually interpret these images, which can be labor-intensive and time-consuming due to the vast amount of data. To address this challenge, machine learning, and deep learning approaches can be utilized to improve the accuracy and efficiency of anomaly detection in MRI scans. This manuscript presents the use of the Deep AlexNet50 model for MRI classification with discriminative learning methods. There are three… More >

  • Open Access

    ARTICLE

    A New Method for Diagnosis of Leukemia Utilizing a Hybrid DL-ML Approach for Binary and Multi-Class Classification on a Limited-Sized Database

    Nilkanth Mukund Deshpande1,2, Shilpa Gite3,4,*, Biswajeet Pradhan5,6, Abdullah Alamri7, Chang-Wook Lee8,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 593-631, 2024, DOI:10.32604/cmes.2023.030704 - 30 December 2023

    Abstract Infection of leukemia in humans causes many complications in its later stages. It impairs bone marrow’s ability to produce blood. Morphological diagnosis of human blood cells is a well-known and well-proven technique for diagnosis in this case. The binary classification is employed to distinguish between normal and leukemia-infected cells. In addition, various subtypes of leukemia require different treatments. These sub-classes must also be detected to obtain an accurate diagnosis of the type of leukemia. This entails using multi-class classification to determine the leukemia subtype. This is usually done using a microscopic examination of these blood… More > Graphic Abstract

    A New Method for Diagnosis of Leukemia Utilizing a Hybrid DL-ML Approach for Binary and Multi-Class Classification on a Limited-Sized Database

  • Open Access

    ARTICLE

    A COVID-19 Detection Model Based on Convolutional Neural Network and Residual Learning

    Bo Wang1,*, Yongxin Zhang1, Shihui Ji2, Binbin Zhang1, Xiangyu Wang1, Jiyong Zhang1

    CMC-Computers, Materials & Continua, Vol.75, No.2, pp. 3625-3642, 2023, DOI:10.32604/cmc.2023.036754 - 31 March 2023

    Abstract A model that can obtain rapid and accurate detection of coronavirus disease 2019 (COVID-19) plays a significant role in treating and preventing the spread of disease transmission. However, designing such a model that can balance the detection accuracy and weight parameters of memory well to deploy a mobile device is challenging. Taking this point into account, this paper fuses the convolutional neural network and residual learning operations to build a multi-class classification model, which improves COVID-19 pneumonia detection performance and keeps a trade-off between the weight parameters and accuracy. The convolutional neural network can extract… More >

  • Open Access

    ARTICLE

    Multi Class Brain Cancer Prediction System Empowered with BRISK Descriptor

    Madona B. Sahaai*, G. R. Jothilakshmi, E. Praveen, V. Hemath Kumar

    Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 1507-1521, 2023, DOI:10.32604/iasc.2023.032256 - 05 January 2023

    Abstract Magnetic Resonance Imaging (MRI) is one of the important resources for identifying abnormalities in the human brain. This work proposes an effective Multi-Class Classification (MCC) system using Binary Robust Invariant Scalable Keypoints (BRISK) as texture descriptors for effective classification. At first, the potential Region Of Interests (ROIs) are detected using features from the accelerated segment test algorithm. Then, non-maxima suppression is employed in scale space based on the information in the ROIs. The discriminating power of BRISK is examined using three machine learning classifiers such as k-Nearest Neighbour (kNN), Support Vector Machine (SVM) and Random Forest More >

  • Open Access

    ARTICLE

    Xception-Fractalnet: Hybrid Deep Learning Based Multi-Class Classification of Alzheimer’s Disease

    Mudiyala Aparna, Battula Srinivasa Rao*

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 6909-6932, 2023, DOI:10.32604/cmc.2023.034796 - 28 December 2022

    Abstract Neurological disorders such as Alzheimer’s disease (AD) are very challenging to treat due to their sensitivity, technical challenges during surgery, and high expenses. The complexity of the brain structures makes it difficult to distinguish between the various brain tissues and categorize AD using conventional classification methods. Furthermore, conventional approaches take a lot of time and might not always be precise. Hence, a suitable classification framework with brain imaging may produce more accurate findings for early diagnosis of AD. Therefore in this paper, an effective hybrid Xception and Fractalnet-based deep learning framework are implemented to classify… More >

  • Open Access

    ARTICLE

    Multi-Tier Sentiment Analysis of Social Media Text Using Supervised Machine Learning

    Hameedur Rahman1, Junaid Tariq2,*, M. Ali Masood1, Ahmad F. Subahi3, Osamah Ibrahim Khalaf4, Youseef Alotaibi5

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5527-5543, 2023, DOI:10.32604/cmc.2023.033190 - 28 December 2022

    Abstract Sentiment Analysis (SA) is often referred to as opinion mining. It is defined as the extraction, identification, or characterization of the sentiment from text. Generally, the sentiment of a textual document is classified into binary classes i.e., positive and negative. However, fine-grained classification provides a better insight into the sentiments. The downside is that fine-grained classification is more challenging as compared to binary. On the contrary, performance deteriorates significantly in the case of multi-class classification. In this study, pre-processing techniques and machine learning models for the multi-class classification of sentiments were explored. To augment the… More >

  • Open Access

    ARTICLE

    Precise Multi-Class Classification of Brain Tumor via Optimization Based Relevance Vector Machine

    S. Keerthi1,*, P. Santhi2

    Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 1173-1188, 2023, DOI:10.32604/iasc.2023.029959 - 29 September 2022

    Abstract The objective of this research is to examine the use of feature selection and classification methods for distinguishing different types of brain tumors. The brain tumor is characterized by an anomalous proliferation of brain cells that can either be benign or malignant. Most tumors are misdiagnosed due to the variability and complexity of lesions, which reduces the survival rate in patients. Diagnosis of brain tumors via computer vision algorithms is a challenging task. Segmentation and classification of brain tumors are currently one of the most essential surgical and pharmaceutical procedures. Traditional brain tumor identification techniques… More >

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