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  • Open Access

    ARTICLE

    Impact of Atrial Septal Defect Closure on Mortality in Older Patients

    Sipawath Khamplod1,2, Yodying Kaolawanich1,2, Khemajira Karaketklang3, Nithima Ratanasit1,2,*

    Congenital Heart Disease, Vol.19, No.1, pp. 93-105, 2024, DOI:10.32604/chd.2024.048631

    Abstract Background: Atrial septal defect (ASD) is a common form of adult congenital heart disease that can lead to long-term adverse outcomes if left untreated. Early closure of ASD has been associated with excellent outcomes and lower complication rates. However, there is limited evidence regarding the prognosis of ASD closure in older adults. This study aims to evaluate the mortality rates in older ASD patients with and without closure. Methods: A retrospective cohort study was conducted on patients aged 40 years or older with ASD between 2001 and 2017. Patients were followed up to assess all-cause mortality. Univariable and multivariable analyses… More > Graphic Abstract

    Impact of Atrial Septal Defect Closure on Mortality in Older Patients

  • Open Access

    ARTICLE

    Analysis of Risk Factors for Early Mortality in Surgical Shunt Palliation: Time for a Change?

    François-Xavier Van Vyve1, Karlien Carbonez2, Jelena Hubrechts2, Geoffroy de Beco1, Jean E. Rubay1, Mona Momeni3, Thierry Detaille4, Alain J. Poncelet1,*

    Congenital Heart Disease, Vol.18, No.5, pp. 539-550, 2023, DOI:10.32604/chd.2023.042344

    Abstract Objectives: Over the last decade, neonatal repair has been advocated for many congenital heart diseases. However, specific subgroups of complex congenital heart disease still require temporary palliation for which both surgical and endovascular techniques are currently available. We reviewed our institutional experience with shunt palliation with an emphasis on risk factors for early mortality. Methods: This is a single-center retrospective study on 175 patients undergoing surgery for central shunt or modified Blalock-Taussig shunt. All data were extracted from a prospectively collected computerized database. We identified risk factors for early mortality by uni- and multi-variable analysis. All data were censored at… More >

  • Open Access

    ARTICLE

    Mortality Rates of Ventricular Septal Defect for Children in Kazakhstan: Spatio-Temporal Epidemiological Appraisal

    Akkerbez Adilbekova1,3,*, Shukhrat Marassulov1, Bakhytzhan Nurkeev1, Saken Kozhakhmetov2, Aikorkem Badambekova3

    Congenital Heart Disease, Vol.18, No.4, pp. 447-459, 2023, DOI:10.32604/chd.2023.028742

    Abstract Objective: The aim is to study the trends in ventricular septal defect (VSD) mortality in children in Kazakhstan. Methods: The retrospective study was done for the period 2011–2020. Descriptive and analytical methods of epidemiology were applied. The universally acknowledged methodology used in sanitary statistics is used to calculate the extensive, crude, and age-specific mortality rates. Results: Kazakhstan is thought to be seeing an increase in mortality from VSDs in children. As a result, this study for the years 2011 to 2020 was conducted to retrospectively assess data from the central registration of the Bureau of National Statistics that was available… More > Graphic Abstract

    Mortality Rates of Ventricular Septal Defect for Children in Kazakhstan: Spatio-Temporal Epidemiological Appraisal

  • Open Access

    ARTICLE

    Preoperative Fasting of More Than 14 Hours Increases the Risk of Time-to-Death after Cardiothoracic Surgery in Children: A Retrospective Cohort Study

    Laortip Rattanapittayaporn, Maliwan Oofuvong*, Jutarat Tanasansuttiporn, Thavat Chanchayanon

    Congenital Heart Disease, Vol.18, No.1, pp. 23-39, 2023, DOI:10.32604/chd.2023.026026

    Abstract Background: Prolonged preoperative fasting can cause hypoglycemia, hyperglycemia, and intravascular volume depletion in children. We aimed to examine whether prolonged preoperative fasting is associated with in-hospital mortality and other morbidities in pediatric cardiothoracic surgery. Methods: This retrospective cohort study included children aged 0–3 years who underwent cardiac surgery between July 2014 and October 2020. The patient demographic data, surgery-related and anesthesia-related factors, and postoperative outcomes, including hypoglycemia, hyperglycemia, sepsis, length of intensive care unit stay, and in-hospital mortality, were recorded. The main exposure and outcome variables were prolonged fasting and time-to-death after surgery, respectively. The associations between prolonged fasting and… More > Graphic Abstract

    Preoperative Fasting of More Than 14 Hours Increases the Risk of Time-to-Death after Cardiothoracic Surgery in Children: A Retrospective Cohort Study

  • Open Access

    REVIEW

    Epidemiology of Breast Cancer

    Chao Shang, Dongkui Xu*

    Oncologie, Vol.24, No.4, pp. 649-663, 2022, DOI:10.32604/oncologie.2022.027640

    Abstract All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence rate was 66.4/100,000 in developed… More >

  • Open Access

    ARTICLE

    Mortality and Long-Term Outcome of Neonates with Congenital Heart Disease and Acute Perinatal Stroke: A Population-Based Case-Control Study

    Eszter Vojcek1,2,*, V. Anna Gyarmathy3,4, Rozsa Graf5, Anna M. Laszlo6, Laszlo Ablonczy7, Zsolt Prodan7, Istvan Seri1,8

    Congenital Heart Disease, Vol.17, No.4, pp. 447-461, 2022, DOI:10.32604/chd.2022.022274

    Abstract Objective: Neonates with congenital heart disease (CHD) and perinatal stroke have high mortality and survivors are at risk for poor long-term neurodevelopmental outcome. The aim of this study was to assess the risk factors and outcome of neonates with both CHD and MRI-confirmed perinatal stroke (Study Group) and compare those to the risk factors and outcome of infants matched for CHD without stroke (Control-1) and of infants matched for MRI-confirmed stroke without CHD (Control-2). Methods: We conducted a population-based case-control study enrolling 28 term neonates with CHD and MRI-confirmed acute perinatal stroke born between 2007–2017 in the Central-Hungarian Region. Each… More > Graphic Abstract

    Mortality and Long-Term Outcome of Neonates with Congenital Heart Disease and Acute Perinatal Stroke: A Population-Based Case-Control Study

  • Open Access

    ARTICLE

    Explainable AI Enabled Infant Mortality Prediction Based on Neonatal Sepsis

    Priti Shaw1, Kaustubh Pachpor2, Suresh Sankaranarayanan3,*

    Computer Systems Science and Engineering, Vol.44, No.1, pp. 311-325, 2023, DOI:10.32604/csse.2023.025281

    Abstract Neonatal sepsis is the third most common cause of neonatal mortality and a serious public health problem, especially in developing countries. There have been researches on human sepsis, vaccine response, and immunity. Also, machine learning methodologies were used for predicting infant mortality based on certain features like age, birth weight, gestational weeks, and Appearance, Pulse, Grimace, Activity and Respiration (APGAR) score. Sepsis, which is considered the most determining condition towards infant mortality, has never been considered for mortality prediction. So, we have deployed a deep neural model which is the state of art and performed a comparative analysis of machine… More >

  • Open Access

    ARTICLE

    Long-Term Outcome and Risk Factor Analysis of Surgical Pulmonary Valve Replacement in Congenital Heart Disease

    Woo Young Park1, Gi Beom Kim1,*, Sang Yun Lee1, Mi Kyoung Song1, Hye Won Kwon1, Hyo Soon An1, Eun Jung Bae1, Sungkyu Cho2, Jae Gun Kwak2, Woong-Han Kim2

    Congenital Heart Disease, Vol.17, No.3, pp. 335-350, 2022, DOI:10.32604/chd.2022.018666

    Abstract Objectives: To establish long-term outcome of surgical pulmonary valve replacement (PVR) in congenital heart disease (CHD) and to identify risk factors for overall mortality, operative mortality, and repetitive PVR. Methods: This is a retrospective study of 375 surgical PVR in 293 patients who underwent surgical PVR for CHD between January 2000 and May 2020. We only included patients with index PVR with previous open-heart surgery regardless of the number of PVRs. The previous surgical history of patients who underwent PVR during the study period was also included. Patients who underwent the Rastelli operation, and those who underwent single PVR without… More >

  • Open Access

    ARTICLE

    Prediction of COVID-19 Transmission in the United States Using Google Search Trends

    Meshrif Alruily1, Mohamed Ezz1,2, Ayman Mohamed Mostafa1,3, Nacim Yanes1,4, Mostafa Abbas5, Yasser El-Manzalawy5,*

    CMC-Computers, Materials & Continua, Vol.71, No.1, pp. 1751-1768, 2022, DOI:10.32604/cmc.2022.020714

    Abstract Accurate forecasting of emerging infectious diseases can guide public health officials in making appropriate decisions related to the allocation of public health resources. Due to the exponential spread of the COVID-19 infection worldwide, several computational models for forecasting the transmission and mortality rates of COVID-19 have been proposed in the literature. To accelerate scientific and public health insights into the spread and impact of COVID-19, Google released the Google COVID-19 search trends symptoms open-access dataset. Our objective is to develop 7 and 14-day-ahead forecasting models of COVID-19 transmission and mortality in the US using the Google search trends for COVID-19… More >

  • Open Access

    ARTICLE

    SutteARIMA: A Novel Method for Forecasting the Infant Mortality Rate in Indonesia

    Ansari Saleh Ahmar1,2,*, Eva Boj del Val3, M. A. El Safty4, Samirah AlZahrani4, Hamed El-Khawaga5,6

    CMC-Computers, Materials & Continua, Vol.70, No.3, pp. 6007-6022, 2022, DOI:10.32604/cmc.2022.021382

    Abstract This study focuses on the novel forecasting method (SutteARIMA) and its application in predicting Infant Mortality Rate data in Indonesia. It undertakes a comparison of the most popular and widely used four forecasting methods: ARIMA, Neural Networks Time Series (NNAR), Holt-Winters, and SutteARIMA. The data used were obtained from the website of the World Bank. The data consisted of the annual infant mortality rate (per 1000 live births) from 1991 to 2019. To determine a suitable and best method for predicting Infant Mortality rate, the forecasting results of these four methods were compared based on the mean absolute percentage error… More >

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