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  • Open Access

    ARTICLE

    Circ_0053943 complexed with IGF2BP3 drives uveal melanoma progression via regulating N6-methyladenosine modification of Epidermal growth factor receptor

    ANDI ZHAO1,2,#, YUE WANG3,#, ZIJIN WANG1,2, QING SHAO1,2, QI GONG1,2, HUI ZHU1,2, SHIYA SHEN1,2, HU LIU1,2,*, XUEJUAN CHEN1,2,*

    Oncology Research, Vol.32, No.5, pp. 983-998, 2024, DOI:10.32604/or.2024.045972

    Abstract Numerous studies have characterized the critical role of circular RNAs (circRNAs) as regulatory factors in the progression of multiple cancers. However, the biological functions of circRNAs and their underlying molecular mechanisms in the progression of uveal melanoma (UM) remain enigmatic. In this study, we identified a novel circRNA, circ_0053943, through re-analysis of UM microarray data and quantitative RT-PCR. Circ_0053943 was found to be upregulated in UM and to promote the proliferation and metastatic ability of UM cells in both in vitro and in vivo settings. Mechanistically, circ_0053943 was observed to bind to the KH1 and KH2 domains of insulin-like growth… More > Graphic Abstract

    <i>Circ_0053943</i> complexed with IGF2BP3 drives uveal melanoma progression via regulating N6-methyladenosine modification of <i>Epidermal growth factor receptor</i>

  • Open Access

    ARTICLE

    Chitosan Modification by New Chromophore 4-(3-(4- nitrophenyl) thioureido) benzoic acid: Synthesis, Characterization and Evaluation

    KAZIM SHAMIM RIZVI, P. K. DUTTA

    Journal of Polymer Materials, Vol.36, No.3, pp. 217-228, 2019, DOI:10.32381/JPM.2019.36.03.2

    Abstract In this investigation we have shown the preparation of carboxylic acid containing new chromophore : 4-(3-(4-nitrophenyl) thioureido) benzoic acid and its use.The chemical modification of chitosan, e.g., chitosan- acid salt complexes is done under mild conditions. The synthesis of chromophore was carried out by conventional methods and the novel polymer complex was soluble in most of the organic solvents. The modified chitosan was analyzed by various techniques like optical properties by UV and SHG spectroscopy which showed red shift. The antibacterial activity showed obvious effect against food pathogenic bacteria. More >

  • Open Access

    ARTICLE

    Influence of Poly (vinyl butyral) Modification on the Mechanical and Thermal Properties of Kevlar Fiber Reinforced Novolac epoxy/multiwalled carbon nanotube nanocomposites

    KAVITA*, R.K. TIWARI

    Journal of Polymer Materials, Vol.36, No.2, pp. 195-205, 2019, DOI:10.32381/JPM.2019.36.02.7

    Abstract The effect of poly (vinyl butyral) and acid functionalized multiwalled carbon nanotubes (f-MWCNT) on the thermal and mechanical performance of Kevlar fiber reinforced novolac epoxy nanocomposites was investigated and presented in this paper. Nanocomposite containing 1.5 wt. % poly (vinyl butyral) and 0.5 wt. % f-MWCNT exhibited best thermal and mechanical properties (except flexural strength) among all the nanocomposites reported here. It showed ~5%, 27% and 126 % improvement in tensile strength, young’s modulus and impact strength respectively as compared to the neat novolac epoxy Kevlar composite.Nanocomposite containing 0.5 wt. % f- MWCNT and 2 wt. % poly (vinyl butyral)… More >

  • Open Access

    ARTICLE

    Robust Color Fastness of Dyed Silk Fibroin Film By Coupling Modification Dyeing with Aniline Diazonium Salt

    ZONGQIAN WANG, HAIWEI YANG, JIAN XING, ZHI LIU*

    Journal of Polymer Materials, Vol.36, No.2, pp. 149-159, 2019, DOI:10.32381/JPM.2019.36.02.4

    Abstract Colored silk fibroin (SF) film can change the proportion of transmitted light composition and therefore shows potential application in optoelectronics area. However, few methods are reported for the preparation of colored SF film with good color fastness. Herein, colored SF film was prepared by coupling modification dyeing (CM-dyeing) of SF tyrosine residues in solution. SF film shows excellent color fastness due to the formation of the azo covalent bond formed by electrophilic substitution reaction between SF tyrosine residues and aniline diazonium salt. Furthermore, compared with the undyed film, the dyed SF film is effectively preserved its mechanical property by the… More >

  • Open Access

    ARTICLE

    Synthesis and Characterization of New Chromophore 4-2-(2-hydroxy-5-(4 nitrophenyl) diazenyl) benzylidene) hydrazinyl) Benzoic Acid and its use in Chitosan Modification

    KAZIM SHAMIM RIZVI, P.K.DUTTA*

    Journal of Polymer Materials, Vol.36, No.1, pp. 75-85, 2019, DOI:10.32381/JPM.2019.36.01.6

    Abstract The present investigation deals with the preparation of carboxylic acid containing new chromophore : 4-2-(2-hydroxy-5-(4-nitrophenyl) diazenyl) benzylidene) hydrazinyl) benzoic acid and its use for chemical modification of chitosan, e.g., chitosan-acid salt complexes under mild conditions. Optical properties of chitosan acid complexes were evaluated by UV and SHG spectroscopy which showed red shift. Antibacterial activity of prepared chitosan acid complexes showed obvious effect against food pathogenic bacteria. The novel polymer complex was soluble in most of the organic solvents. More >

  • Open Access

    ARTICLE

    Synthesis and Characterization of poly (N-glycidyl-2- oxazolidone) Using a Green and Efficient Catalyst

    SORAYA SEGHIER1,2,*, MOHAMMED BELBACHIR1

    Journal of Polymer Materials, Vol.38, No.3-4, pp. 205-218, 2021, DOI:10.32381/JPM.2021.38.3-4.3

    Abstract In the present paper, we report the synthesis of a new amino polymer made of oxazolidinone using an efficient ecocatalyst called Maghnite-H+. The synthesis process contains two steps: the first consists to the preparation of an amino oxiran 3-(oxiran-ylmethyl) oxazolidin- 2-one (OMO) by a substitution reaction of epichlorhydrin by 2-oxazolidinone, the second step concerns a green polymerization of the resultant oxiran by a ring opening reaction catalysed by Maghnite-H+. The polymer have been successfully prepared and characterized by various techniques, such as 1H NMR, 13C NMR, IR, which were used to elucidate the structural characteristics of the resulting polymers. The… More >

  • Open Access

    REVIEW

    A Brief Review of Surface Modification of Carbonyl Iron Powders (CIPs) for Magnetorheological Fluid Applications

    THIRUMALAISAMY SURYAPRABHAA, CHUNGHYUN CHOIA, ZUBAIR AHMED CHANDIOB, LAWRENCE ROBERT MSALILWAB, TAEGWANG YUNC,*, JUN YOUNG CHEONGB,*, BYUNGIL HWANGA,*

    Journal of Polymer Materials, Vol.40, No.3-4, pp. 191-204, 2023, DOI:10.32381/JPM.2023.40.3-4.5

    Abstract Magnetorheological fluids (MRFs) is a smart fluid system that exhibits swift and reversible alterations in their rheological characteristics when exposed to an external magnetic field. MRFs are used for applications in various areas, including automotive systems, robotics, aerospace, and civil engineering. The performance of MRFs depends on the behavior of the dispersed magnetic particles, necessitating thoughtful consideration of particle traits to optimize fluid performance. Carbonyl Iron Powders (CIPs), high purity iron (>98%) reduced from penta carbonyl iron, are widely employed in MRFs due to their exceptional magnetic characteristics. Nevertheless, the innate surfaces of CIPs tend to conglomerate, leading to compromises… More >

  • Open Access

    ARTICLE

    Study of the Neutron Radiation Effect on Bi-oriented Polyethylene Naphthalate Structure

    A. BELOUADAH1, S. BERDOUS1,3, D. BERDOUS2, M. IZERROUKEN4, N. SAIDI-AMROUN1

    Journal of Polymer Materials, Vol.39, No.1-2, pp. 1-15, 2022, DOI:10.32381/JPM.2022.39.1-2.1

    Abstract In this work, neutron induced structural modifications, on the biaxially-oriented polyethylene naphthalate (BOPEN) film, were studied by X-ray diffraction technique (XRD), Fourier transform infrared spectroscopy (FTIR/ATR), scanning electron microscopy (SEM) and polarized light optical microscopy (PLOM). The irradiation with neutron was carried out, under air, at room temperature. The changes of the structure, in volume and in surface were evaluated under the impact of neutron’s flux composed by thermally neutrons and fast neutrons. The X-ray technique showed the effect of the neutron flux’s fluence on the crystallinity of the BOPEN, which was also determined through the FTIR/ATR spectroscopy, traduced by… More >

  • Open Access

    ARTICLE

    Impact on Mechanical Properties of Surface Treated Coconut Leaf Sheath Fiber/Sic Nano Particles Reinforced Phenol-formaldehyde Polymer Composites

    B. BRAILSON MANSINGH1, K. L. NARASIMHAMU2, K. C. VARAPRASAD3, J. S. BINOJ4,*, A. RADHAKRISHNAN5, ALAMRY ALI6

    Journal of Polymer Materials, Vol.40, No.1-2, pp. 71-82, 2023, DOI:10.32381/JPM.2023.40.1-2.6

    Abstract Several agro-wastes are rich in natural fibers and finds scope to be used as reinforcement in composite industry. These natural fibers have some advantages over man-made fibers, including low cost, light weight, renewable nature, high specific strength and modulus, and availability in various forms worldwide. In this paper, the effect of surface modification of leaf sheath coconut fiber (LSF) (an agro-waste) reinforced in phenol formaldehyde matrix composites with silicon carbide (SiC) nano particles as filler material were investigated for its mechanical characteristics. The investigation portrays that coconut LSF (CLSF) modified with potassium permanganate reinforced polymer composite with SiC nano particles… More >

  • Open Access

    ARTICLE

    EXPERIMENTAL STUDY OF ENHANCED NUCLEATE BOILING HEAT TRANSFER ON UNIFORM AND MODULATED POROUS STRUCTURES

    Calvin Hong Lia, G. P. Petersonb,*

    Frontiers in Heat and Mass Transfer, Vol.1, No.2, pp. 1-10, 2010, DOI:10.5098/hmt.v1.2.3007

    Abstract An experimental investigation of the Critical Heat Flux (CHF) and heat transfer coefficient (HTC) of two-phase heat transfer of de-Ionized (DI) water, pool boiling was conducted using several kinds of sintered copper microparticle porous uniform and modulated structures. The modulated porous structure reached a heat flux of 450 W/cm2 and a heat transfer coefficient of 230,000 W/m2K. The thick and thin uniform porous structures achieved CHFs of 290 W/cm2 and 227 W/cm2 , respectively, and heat transfer coefficients of 118,000 W/m2K and 104,000 W/m2K. The mechanisms for the dramatically improved CHFs and HTCs were identified with assistance of a visualization… More >

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