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  • Open Access

    ARTICLE

    Glycyrrhizic acid alleviates lung injury in sepsis through SIRT1/HMGB1 pathway

    BINGJIE LIN1, XIAOBO YING2, CHUANLING ZHANG3,*, GUOJUN ZHANG1,*

    BIOCELL, Vol.48, No.11, pp. 1613-1623, 2024, DOI:10.32604/biocell.2024.053652 - 07 November 2024

    Abstract Objectives: This study explores the protective effects of glycyrrhizic acid (GA) on sepsis-induced cellular damage and inflammation in acute lung injury (ALI), specifically through the modulation of the sirtuin 1 (SIRT1) and high mobility group box 1 (HMGB1) pathway. Methods: The study employed two experimental models: lipopolysaccharide (LPS)-induced BEAS-2B human lung epithelial cells and cecal ligation and puncture (CLP) rats, to simulate sepsis conditions. The cell model involved treatments with LPS, GA, control siRNA (si-NC), and SIRT1-specific siRNA (si-SIRT1). Evaluations included cell viability, apoptosis, and cytokine production. In the rat model, treatments included GA and… More >

  • Open Access

    RETRACTION

    Retraction: Long noncoding RNA CAMTA1 promotes proliferation and mobility of the human breast cancer cell line MDA-MB-231 via targeting miR-20b

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.10, pp. 1679-1680, 2024, DOI:10.32604/or.2024.056894 - 18 September 2024

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    An Enhanced Multiview Transformer for Population Density Estimation Using Cellular Mobility Data in Smart City

    Yu Zhou1, Bosong Lin1, Siqi Hu2, Dandan Yu3,*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 161-182, 2024, DOI:10.32604/cmc.2024.047836 - 25 April 2024

    Abstract This paper addresses the problem of predicting population density leveraging cellular station data. As wireless communication devices are commonly used, cellular station data has become integral for estimating population figures and studying their movement, thereby implying significant contributions to urban planning. However, existing research grapples with issues pertinent to preprocessing base station data and the modeling of population prediction. To address this, we propose methodologies for preprocessing cellular station data to eliminate any irregular or redundant data. The preprocessing reveals a distinct cyclical characteristic and high-frequency variation in population shift. Further, we devise a multi-view More >

  • Open Access

    ARTICLE

    A Fault-Tolerant Mobility-Aware Caching Method in Edge Computing

    Yong Ma1, Han Zhao2, Kunyin Guo3,*, Yunni Xia3,*, Xu Wang4, Xianhua Niu5, Dongge Zhu6, Yumin Dong7

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 907-927, 2024, DOI:10.32604/cmes.2024.048759 - 16 April 2024

    Abstract Mobile Edge Computing (MEC) is a technology designed for the on-demand provisioning of computing and storage services, strategically positioned close to users. In the MEC environment, frequently accessed content can be deployed and cached on edge servers to optimize the efficiency of content delivery, ultimately enhancing the quality of the user experience. However, due to the typical placement of edge devices and nodes at the network’s periphery, these components may face various potential fault tolerance challenges, including network instability, device failures, and resource constraints. Considering the dynamic nature of MEC, making high-quality content caching decisions… More >

  • Open Access

    ARTICLE

    RPL-Based IoT Networks under Decreased Rank Attack: Performance Analysis in Static and Mobile Environments

    Amal Hkiri1,*, Mouna Karmani1, Omar Ben Bahri2, Ahmed Mohammed Murayr2, Fawaz Hassan Alasmari2, Mohsen Machhout1

    CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 227-247, 2024, DOI:10.32604/cmc.2023.047087 - 30 January 2024

    Abstract The RPL (IPv6 Routing Protocol for Low-Power and Lossy Networks) protocol is essential for efficient communication within the Internet of Things (IoT) ecosystem. Despite its significance, RPL’s susceptibility to attacks remains a concern. This paper presents a comprehensive simulation-based analysis of the RPL protocol’s vulnerability to the decreased rank attack in both static and mobile network environments. We employ the Random Direction Mobility Model (RDM) for mobile scenarios within the Cooja simulator. Our systematic evaluation focuses on critical performance metrics, including Packet Delivery Ratio (PDR), Average End to End Delay (AE2ED), throughput, Expected Transmission Count More >

  • Open Access

    ARTICLE

    Phase-Field Simulation of δ Hydride Precipitation with Interfacial Anisotropy

    Hailong Nie1, Xincheng Shi1, Wenkui Yang1, Kaile Wang1, Yuhong Zhao2,1,3,*

    CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 1425-1443, 2023, DOI:10.32604/cmc.2023.044510 - 29 November 2023

    Abstract Previous studies of hydride in zirconium alloys have mainly assumed an isotropic interface. In practice, the difference in crystal structure at the interface between the matrix phase and the precipitate phase results in an anisotropic interface. With the purpose of probing the real evolution of hydrides, this paper couples an anisotropy function in the interfacial energy and interfacial mobility. The influence of anisotropic interfacial energy and interfacial mobility on the morphology of hydride precipitation was investigated using the phase-field method. The results show that the isotropy hydride precipitates a slate-like morphology, and the anisotropic hydride… More >

  • Open Access

    ARTICLE

    Improved QoS-Secure Routing in MANET Using Real-Time Regional ME Feature Approximation

    Y. M. Mahaboob John1,*, G. Ravi2

    Computer Systems Science and Engineering, Vol.46, No.3, pp. 3653-3666, 2023, DOI:10.32604/csse.2023.036916 - 03 April 2023

    Abstract Mobile Ad-hoc Network (MANET) routing problems are thoroughly studied several approaches are identified in support of MANET. Improve the Quality of Service (QoS) performance of MANET is achieving higher performance. To reduce this drawback, this paper proposes a new secure routing algorithm based on real-time partial ME (Mobility, energy) approximation. The routing method RRME (Real-time Regional Mobility Energy) divides the whole network into several parts, and each node’s various characteristics like mobility and energy are randomly selected neighbors accordingly. It is done in the path discovery phase, estimated to identify and remove malicious nodes. In… More >

  • Open Access

    ARTICLE

    Interaction of Foam and Microemulsion Components in Low-Tension-Gas Flooding

    Jing Zhao, Jun Yang*

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.7, pp. 1951-1961, 2023, DOI:10.32604/fdmp.2023.026115 - 08 March 2023

    Abstract Low-Tension-Foam (LTF) flooding is an emerging enhanced oil recovery technique for low-permeability carbonate reservoirs. Foam capacity is closely related to the salinity environment (or, equivalently, the phase behavior of the oil/water/surfactant system). Therefore, the interactions between microemulsion and foam components are of primary importance in the LTF process. In this study, the phase behavior of an oil/water/surfactant system under equilibrium is analyzed, firstly by assuming perfect mixing. Meanwhile, the formation kinetics of microemulsion are monitored through a novel low-field NMR technique, which is able to provide quantitative assessment on the microemulsion evolution characteristics. Then, foam More >

  • Open Access

    ARTICLE

    ILSM: Incorporated Lightweight Security Model for Improving QOS in WSN

    Ansar Munir Shah1, Mohammed Aljubayri2, Muhammad Faheem Khan1, Jarallah Alqahtani2,*, Mahmood ul Hassan3, Adel Sulaiman2, Asadullah Shaikh2

    Computer Systems Science and Engineering, Vol.46, No.2, pp. 2471-2488, 2023, DOI:10.32604/csse.2023.034951 - 09 February 2023

    Abstract In the network field, Wireless Sensor Networks (WSN) contain prolonged attention due to afresh augmentations. Industries like health care, traffic, defense, and many more systems espoused the WSN. These networks contain tiny sensor nodes containing embedded processors, Tiny OS, memory, and power source. Sensor nodes are responsible for forwarding the data packets. To manage all these components, there is a need to select appropriate parameters which control the quality of service of WSN. Multiple sensor nodes are involved in transmitting vital information, and there is a need for secure and efficient routing to reach the… More >

  • Open Access

    ARTICLE

    Efficient Optimal Routing Algorithm Based on Reward and Penalty for Mobile Adhoc Networks

    Anubha1, Ravneet Preet Singh Bedi2, Arfat Ahmad Khan3,*, Mohd Anul Haq4, Ahmad Alhussen5, Zamil S. Alzamil4

    CMC-Computers, Materials & Continua, Vol.75, No.1, pp. 1331-1351, 2023, DOI:10.32604/cmc.2023.033181 - 06 February 2023

    Abstract Mobile adhoc networks have grown in prominence in recent years, and they are now utilized in a broader range of applications. The main challenges are related to routing techniques that are generally employed in them. Mobile Adhoc system management, on the other hand, requires further testing and improvements in terms of security. Traditional routing protocols, such as Adhoc On-Demand Distance Vector (AODV) and Dynamic Source Routing (DSR), employ the hop count to calculate the distance between two nodes. The main aim of this research work is to determine the optimum method for sending packets while… More >

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