HONGQIANG ZHAO1,2, QI LIU3, HAORUN LIU3, WEIMIN LI3,*, JIANGYANG LU1,*
BIOCELL, Vol.46, No.5, pp. 1299-1308, 2022, DOI:10.32604/biocell.2022.017217
Abstract HMGN2 have functions in inflammatory response. However, the role of HMGN2 in severe acute pancreatitis (SAP) remains unclear. Here, our study was to discuss the role and regulatory mechanism ofHMGN2 in SAP. In this study, the SAP cell model of AR42J was used to study the function and mechanism of HMGN2 in SAP. The protein expression in cells and serums were examined by western blot and ELISA assay. qPCR was used to test the transcriptional RNA level. Cell viability were examined by MTT assay. Luciferase assay was used to evaluate the interaction between gene and gene. Our results showed that… More >
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