Zhangjie Jiang*1, Yida Zhang†1, Runfu Cao†, Li Li‡, Kezhao Zhong†, Qingsheng Chen†, Jianjun Xiao†
Oncology Research, Vol.25, No.7, pp. 1081-1087, 2017, DOI:10.3727/096504016X14831120463349
Abstract miRNAs play a key role in the carcinogenesis of many cancers, including bladder cancer. In the current
study, the role of miR-5195-3p, a quite recently discovered and poorly studied miRNA, in the proliferation
and invasion of human bladder cancer cells was investigated. Our data displayed that, compared with healthy
volunteers (control) and SU-HUC-1 normal human bladder epithelial cells, miR-5195-3p was sharply downregulated in bladder cancer patients and five human bladder cancer cell lines. The oligo miR-5195-3p mimic
or miR-5195-3p antagomir was subsequently transfected into both T24 and BIU-87 bladder cancer cell
lines. The miR-5195-3p mimic… More >
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