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    ARTICLE

    MicroRNA-433 Represses Proliferation and Invasion of Colon Cancer Cells by Targeting Homeobox A1

    Heming Li*1, Junfeng Li*1, Taisheng Yang*, Shuwen Lin, Heng Li

    Oncology Research, Vol.26, No.2, pp. 315-322, 2018, DOI:10.3727/096504017X15067856789781

    Abstract The aberrant expression of miR-433 has been validated in some types of cancers. However, the expression profile and the biological function of miR-433 on colon cancer are still elusive. This study was designed to investigate the function of miR-433 on the proliferation and invasion of colon cancer cells. We detected the expression of miR-433 in colon cancer tissues, adjacent normal tissues, and cell lines. CCK8 and Transwell assays were performed to explore the impact of miR-433 on colon cancer cell proliferation and invasion. The luciferase reporter assay was applied to identify the direct target of More >

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