Encieh Choghaei*, Gholamreza Khamisipour†, Mojtaba Falahati*, Behrooz Naeimi†, Majid Mossahebi-Mohammadi‡, Rahim Tahmasebi†, Mojtaba Hasanpour†, Shakib Shamsian†, Zahra Sadat Hashemi§
Oncology Research, Vol.23, No.1-2, pp. 69-78, 2015, DOI:10.3727/096504015X14478843952906
Abstract Breast cancer is the most commonly occurring cancer among women. MicroRNAs as noncoding small RNA
molecules play pivotal roles in cancer-related biological processes. Increased levels of microRNA-29a in the
serum of breast cancer patients have been reported. Since heat shock proteins (HSPs) play important roles in cell
events, the quantitative fluctuations in their cellular levels could be deemed as key indicators of how the exerted
treatment alters cell behavior. In this regard, using an antisense small RNA, we attempted to investigate the effects
of miR-29a knockdown on the expression of HSPs genes in the MCF-7… More >
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