Yinfang Wu*, Jun Zhang†, Yu Zheng‡, Cheng Ma‡, Xing-E Liu§, Xiaodong Sun*‡
Oncology Research, Vol.26, No.1, pp. 157-171, 2018, DOI:10.3727/096504017X15031557924150
Abstract This work aims to elucidate the effects and the potential underlying mechanisms of microRNA-216a-3p (miR-
216a-3p) on the proliferation, migration, and invasion of gastric cancer (GC) cells. In this study, we revealed
that the expression of miR-216a-3p was significantly elevated in GC tissues and cell lines. The different expression level of miR-216a-3p was firmly correlated with clinicopathological characteristics of GC patients. We
next demonstrated that upregulation of miR-216a-3p could dramatically promote the ability of proliferation,
migration, and invasion of GC cells using a series of experiments, whereas downregulation essentially inhibited
these properties. Additionally, through bioinformatics More >
Login
Register
