Kang Zhu*, Ying He†, Cui Xia*, Jing Yan*, Jin Hou*, Demin Kong*, Yeye Yang*, Guoxi Zheng*
Oncology Research, Vol.24, No.3, pp. 145-151, 2016, DOI:10.3727/096504016X14611963142290
Abstract Nasopharyngeal carcinoma (NPC) is a highly metastatic cancer, frequently occurring in Southeast Asia and
Southern China. Several microRNAs (miRNAs) have been shown to have an inhibitive effect on NPC, while
the effect of miR-15a on NPC remains unclear. Thus, our study aimed to investigate the potential effect of
miR-15a on NPC cell proliferation, apoptosis, and possible functional mechanism. Human NPC CNE1 cells
were transfected with miR-15a mimics, miR-15a inhibitors, or a control. Afterward, cell viability and apoptosis
were assayed by using CCK-8, BrdU assay, and flow cytometry. Moreover, Western blot was used to detect
the… More >
Login
Register
