Qurat-Ul-Ain Raza^1,2, Abdur Rehim^1,*, Muhammad Amjad Bashir^1,3,*, Mingzheng Duan⁴, Yucong Geng³, Abdulwahed Fahad Alrefaei⁵

Phyton-International Journal of Experimental Botany, Vol.93, No.12, pp. 3531-3548, 2024, DOI:10.32604/phyton.2024.057356 - 31 December 2024

Abstract Chemical fertilizers have contributed to improving crop production and coping with food safety challenges, but their excessive application in agriculture has resulted in soil and environmental problems. The present study was performed to assess the potential of biostimulants as an alternative to chemical fertilizers. A pot experiment was conducted to examine the response of okra against different biostimulants, including glycine (G.L.), lysine (L.Y.), aspartic acid (A.A.), vitamin B complex (V.B.), and chemical fertilizers (control; C.K.). The results revealed that G.L. and V.B. significantly improved chlorophyll a (12.51%) and chlorophyll b (7.14%) contents in okra… More >

CHUNLING LIANG^1,#, JING CHEN^2,#, XIAOJIE CHEN¹, WEI YAN³, JIE YU^4,*

BIOCELL, Vol.48, No.7, pp. 1105-1113, 2024, DOI:10.32604/biocell.2024.050509 - 03 July 2024

Abstract Background: A differential gene, triggering receptor expressed on myeloid cells 1 (TREM1), was identified in blood sequencing datasets from myocardial infarction patients and healthy controls. Myocardial fibrosis following myocardial infarction significantly contributes to cardiac dysfunction. Objectives: This study aimed to unveil the intrinsic regulatory mechanism of TREM1 in myocardial fibrosis. Methods: Mimicking pathology by angiotensin II (Ang II) treatment of human cardiac fibroblasts (HCFs), the impacts of TREM1 knockdown on its proliferation, migration, and secretion of the pro-fibrotic matrix were identified. Using the Human Transcription Factor Database (HumanTFDB) website, lysine-specific demethylase 5B (KDM5B) was found to… More >

Talha Imtiaz Baig^1,*, Yaser Daanial Khan¹, Talha Mahboob Alam², Bharat Biswal³, Hanan Aljuaid⁴, Durdana Qaiser Gillani⁵

CMC-Computers, Materials & Continua, Vol.71, No.1, pp. 215-230, 2022, DOI:10.32604/cmc.2022.021849 - 03 November 2021

Abstract Lysine Lipoylation is a protective and conserved Post Translational Modification (PTM) in proteomics research like prokaryotes and eukaryotes. It is connected with many biological processes and closely linked with many metabolic diseases. To develop a perfect and accurate classification model for identifying lipoylation sites at the protein level, the computational methods and several other factors play a key role in this purpose. Usually, most of the techniques and different traditional experimental models have a very high cost. They are time-consuming; so, it is required to construct a predictor model to extract lysine lipoylation sites. This… More >

Danlong Jing^1,2, Nan Wang¹, Nan Lu¹, Guanzheng Qu³, Guolu Liang², Wenjun Ma¹, Shougong Zhang^1,*, Junhui Wang^1,*

Phyton-International Journal of Experimental Botany, Vol.91, No.3, pp. 507-524, 2022, DOI:10.32604/phyton.2022.017644 - 26 October 2021

Abstract Lysine acetylation, a reversible and dynamic post-translational modification, plays pivotal roles in regulating many biological processes in plants. However, the information of lysine acetylation during flower development of woody angiosperm remains unclear. Herein, we identified a total of 667 lysine acetylation sites in 467 proteins in flower buds of Catalpa Bungei. The acetylated proteins were mainly involved in the pathways of carbon metabolism, glycometabolism and oxidative phosphorylation. Using functional enrichment analysis, 61 and 13 acetylated proteins were involved in the glycometabolism and oxidative phosphorylation pathways, respectively. This suggests that lysine acetylated proteins play critical roles in… More >

Shaheena Khanum¹, Muhammad Adeel Ashraf², Asim Karim¹, Bilal Shoaib³, Muhammad Adnan Khan⁴, Rizwan Ali Naqvi⁵, Kamran Siddique⁶, Mohammed Alswaitti^6,*

CMC-Computers, Materials & Continua, Vol.66, No.2, pp. 2165-2181, 2021, DOI:10.32604/cmc.2020.013646 - 26 November 2020

Abstract Glycation is a non-enzymatic post-translational modification which assigns sugar molecule and residues to a peptide. It is a clinically important attribute to numerous age-related, metabolic, and chronic diseases such as diabetes, Alzheimer’s, renal failure, etc. Identification of a non-enzymatic reaction are quite challenging in research. Manual identification in labs is a very costly and time-consuming process. In this research, we developed an accurate, valid, and a robust model named as Gly-LysPred to differentiate the glycated sites from non-glycated sites. Comprehensive techniques using position relative features are used for feature extraction. An algorithm named as a… More >

Donglin Tang^1,2, Shanmugam Thiyagarajan^2,3, Bart A.J. Noordover^1,*, Cor E. Koning¹, Daan S. van Es³, Jacco van Haveren

Journal of Renewable Materials, Vol.1, No.3, pp. 222-230, 2013, DOI:10.7569/JRM.2013.634116

Abstract A series of fully renewable poly(ester urethane urea)s (PEUs) were synthesized from bio-based starting materials, e.g., the polyester diol, the diisocyanates including L-lysine diisocyanate (LDI) and isoidide diisocyanate (IIDI), the chain-extenders including 1,4-diaminobutane (bDA), diaminoisoidide (iDA) and di(aminobutyl) urea (b2 DA). It is found that the PEU based on the novel diisocyanate, IIDI, exhibits satisfactory thermal and mechanical properties. The LDI-based PEUs show less favorable thermal and mechanical properties than the IIDI-based counterpart, since the chemical structure of LDI is less regular than that of IIDI. However, by introducing a urea-containing dimeric diamine (b2 DA) More >