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  • Open Access

    ARTICLE

    DAPK2 promotes autophagy to accelerate the progression of ossification of the posterior longitudinal ligament through the mTORC1 complex

    LEI SHI1,#, JIANSHI YIN2,#, YU CHEN1, JIANGANG SHI1, JINHAO MIAO1,*

    BIOCELL, Vol.48, No.9, pp. 1389-1400, 2024, DOI:10.32604/biocell.2024.049562 - 04 September 2024

    Abstract Background: Ossification of the posterior longitudinal ligament (OPLL) is a prevalent condition in orthopedics. While death-associated protein kinase 2 (DAPK2) is known to play roles in cellular apoptosis and autophagy, its specific contributions to the advancement of OPLL are not well understood. Methods: Ligament fibroblasts were harvested from patients diagnosed with OPLL. Techniques such as real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) and Western blot analysis were employed to assess DAPK2 levels in both ligament tissues and cultured fibroblasts. The extent of osteogenic differentiation in these cells was evaluated using an alizarin red S (ARS) staining. Additionally,… More >

  • Open Access

    ARTICLE

    Tendency to Avoid Physical Activity and Sport: Associations with Weight Stigma, and Psychological Distress in a Two-Wave Longitudinal Study

    Saffari Mohsen1,2,#, Yi-Ching Lin3,#, Po-Ching Huang4, Yu-Ting Huang5, Ru-Yi Huang6,7, Chi Hsien Huang8,9,*, Jung-Sheng Chen10, Wai Chuen Poon11, Mark D. Griffiths12, Chung-Ying Lin5,13,14,15,*

    International Journal of Mental Health Promotion, Vol.26, No.8, pp. 633-641, 2024, DOI:10.32604/ijmhp.2024.053432 - 30 August 2024

    Abstract Background: Physical inactivity is a major public health problem worldwide that results in physical and mental health problems. One major issue for physical inactivity is weight stigma (WS), especially perceived WS, which could lead to a tendency to avoid physical activity (PA). To better understand the association between perceived WS and PA, knowledge of the likely mediators in this association such as weight bias internalization (WBI) and psychological distress were investigated in the present study. Methods: Using a two-wave longitudinal study and convenient sampling, 388 Taiwanese participants (55% females; mean age = 29.7 years [SD… More >

  • Open Access

    ARTICLE

    Factor Structure and Longitudinal Invariance of the CES-D across Diverse Residential Backgrounds in Chinese Adolescents

    Yanjing Cao1, Chenchen Xu1,2, Qi Li1, Shan Lu1,2,*, Jing Xiao1,*

    International Journal of Mental Health Promotion, Vol.26, No.4, pp. 261-269, 2024, DOI:10.32604/ijmhp.2024.043729 - 04 May 2024

    Abstract Background: Valid and reliable measures of depressive symptoms are crucial for understanding risk factors, outcomes, and interventions across rural and urban settings. Despite this need, the longitudinal invariance of these measures over time remains understudied. This research explores the structural components of the Center for Epidemiological Studies Depression Scale (CES-D) and examines its consistency across various living environments and temporal stability in a cohort of Chinese teenagers. Method: In the initial phase, 1,042 adolescents furnished demographic details and undertook the CES-D assessment. After a three-month interval, 967 of these participants repeated the CES-D evaluation. The… More >

  • Open Access

    ARTICLE

    Distribution Line Longitudinal Protection Method Based on Virtual Measurement Current Restraint

    Wei Wang1, Yang Yu1, Simin Luo2,*, Wenlin Liu2, Wei Tang1, Yuanbo Ye1

    Energy Engineering, Vol.121, No.2, pp. 315-337, 2024, DOI:10.32604/ee.2023.042082 - 25 January 2024

    Abstract As an effective approach to achieve the “dual-carbon” goal, the grid-connected capacity of renewable energy increases constantly. Photovoltaics are the most widely used renewable energy sources and have been applied on various occasions. However, the inherent randomness, intermittency, and weak support of grid-connected equipment not only cause changes in the original flow characteristics of the grid but also result in complex fault characteristics. Traditional overcurrent and differential protection methods cannot respond accurately due to the effects of unknown renewable energy sources. Therefore, a longitudinal protection method based on virtual measurement of current restraint is proposed More >

  • Open Access

    ARTICLE

    Cross Flow Characteristics and Heat Transfer of Staggered Tubes Bundle: A Numerical Study

    Husam Rashid Hudear*, Saad Najeeb Shehab

    Frontiers in Heat and Mass Transfer, Vol.21, pp. 367-383, 2023, DOI:10.32604/fhmt.2023.042639 - 30 November 2023

    Abstract This paper presents a numerical emulation study of heat transmission through tube banks in three-dimensions. Staggered configuration is displayed by fluid dynamics using computer programs (CFD) software (ANSYS fluent). The computer model is used to predict the values of the Nusselt number when changing the values of heat flux and longitudinal pitch. The longitudinal pitch (SL/D) of 1.3, 1.8, and 2.4 mm. The transverse pitch (ST/D) of 1.5 mm, and also considered Reynolds numbers 10000, 13000, 17000, and 190000. The staggered configuration of the tube bundle is demonstrated to investigate the impact of this arrangement More >

  • Open Access

    PROCEEDINGS

    Study on the Influence of the Longitudinal Position of the Fire Source on the Movement Behavior of the Asymmetric Flow Field in Tunnel Fire

    Lu He1,*, Yuhang Zhou1, Guoqing Zhu1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.2, pp. 1-1, 2023, DOI:10.32604/icces.2023.08939

    Abstract The longitudinal position of the fire source is one of the key parameters affecting the flow field characteristics in a long-distance tunnel. In this paper, a series of numerical simulations were carried out to analyze the influence of the longitudinal position and the heat release rate (HRR) on the induced airflow on both sides of the fire source and the smoke movement behaviors characteristics in the long-distance tunnel. It is found that under the induction of thermal pressure, an asymmetric induced air flow is formed near the fire source, resulting in asymmetric dynamic parameters of More >

  • Open Access

    PROCEEDINGS

    Virtual Manipulation of Tail Postures of a Barn Owl Demonstrates Longitudinal Static Unstability when Gliding

    Changyao Chen1, Jialei Song1,*, Ling Yin1, Yizhe Li2, Zheng Yuan2, Yuhan Li3

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.1, pp. 1-1, 2023, DOI:10.32604/icces.2023.09859

    Abstract Bird can switch between high maneuverability and high stability due to its ability to substantially morph wings and tail. Tail as an auxiliary lift surface, plays an important role on lift and drag production and also significantly affects the longitudinal stability. In this study, we reconstruct a high-fidelity barn owl model using the point cloud of its surface obtained from high-speed photogrammetry, and simulate the fluid dynamics using a commercial software. By virtually manipulating the tail to a series of postures, we analyze the aerodynamics and static stability for each tail posture, investigating the strategy More >

  • Open Access

    ARTICLE

    Association between Occupational Change Trajectories and Mental Health: Results from the Korean Longitudinal Study of Aging

    Jeong Min Yang1,2, Hyeon Ji Lee1, Jae Hyun Kim1,2,3,*

    International Journal of Mental Health Promotion, Vol.25, No.4, pp. 579-594, 2023, DOI:10.32604/ijmhp.2022.027498 - 01 March 2023

    Abstract Objectives: This study was to longitudinally investigate the association between occupational change trajectories and mental health in the Korean population aged 45 years and older from the Korean Longitudinal Study of Aging (KLoSA). Methods: After excluding missing values, the data of 6,224 participants from the first to eighth waves of the KLoSA were analyzed using t-test, Analysis of variance (ANOVA), Group-based Trajectory Model (GBTM) from 1–5th KLoSA and Time-Lagged Generalized estimating equation (GEE) model from 5–8th KLoSA to analyze the association between occupational change trajectories and mental health in the Korean population aged 45 years and older. Results:More >

  • Open Access

    ARTICLE

    Isogeometric Analysis of Longitudinal Displacement of a Simplified Tunnel Model Based on Elastic Foundation Beam

    Zhihui Xiong*, Lei Kou, Jinjie Zhao, Hao Cui, Bo Wang

    CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.1, pp. 803-824, 2023, DOI:10.32604/cmes.2023.024833 - 05 January 2023

    Abstract Serious uneven settlement of the tunnel may directly cause safety problems. At this stage, the deformation of the tunnel is predicted and analyzed mainly by numerical simulation, while the commonly used finite element method (FEM) uses low-order continuous elements. Therefore, the accuracy of tunnel settlement prediction is not enough. In this paper, a method is proposed to study the vertical deformation of the tunnel by using the combination of isogeometric analysis (IGA) and Bézier extraction operator. Compared with the traditional IGA method, this method can be easily integrated into the existing FEM framework, and ensure… More >

  • Open Access

    ARTICLE

    PERFORMANCE ANALYSIS OF LONGITUDINAL FIN JET PLATE SOLAR AIR HEATER UNDER CROSS FLOW CONDITION

    Rajen Kumar Nayaka,* , Ravi Shankar Prasada,† , Ujjwal Kumar Nayaka, Amit Kumar Guptab

    Frontiers in Heat and Mass Transfer, Vol.19, pp. 1-12, 2022, DOI:10.5098/hmt.19.22

    Abstract The present experimental work has been carried out for a solar air heater under cross flow condition having inline hole jet plate between bottom plate and absorber plate with longitudinal fins underside the absorber surface. The performance of this inline hole jet plate solar air heater is compared with the performance of jet plate solar air heaters without longitudinal fins under cross and non-cross flow conditions for similar geometrical and operational parameters. Results are presented for mass flow rates of air, 1 = 0.020 - 0.070 kg/sec, 2 = 0.018 - 0.041 kg/sec, flow Reynolds number, Reja2More >

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