Jian Ding*, Fuqing Wang†, Tiangang Xiang‡, Meng Qiao§
Oncology Research, Vol.26, No.7, pp. 1047-1053, 2018, DOI:10.3727/096504018X15152037713570
Abstract The aberrant expression of long noncoding RNAs (lncRNAs) is implicated in cancer development and
progression. This study was aimed to investigate the expression and clinical significance of lncRNA
NONHSAT129183 in papillary thyroid cancer (PTC), and to explore its roles in PTC cell proliferation, migration, and invasion. Our results demonstrate that lncRNA NONHSAT129183 is upregulated in human PTC tissues when compared with that in adjacent noncancerous thyroid tissue. Moreover, its expression is correlated
with tumor size, lymph node metastasis, and TNM stage in PTC patients. lncRNA NONHSAT129183 silencing
also significantly suppressed cell proliferation, migration, and invasion More >
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