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  • Open Access

    ARTICLE

    Noninvasive Radar Sensing Augmented with Machine Learning for Reliable Detection of Motor Imbalance

    Faten S. Alamri1, Adil Ali Saleem2, Muhammad I. Khan3, Hafeez Ur Rehman Siddiqui2, Amjad Rehman3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074679 - 29 January 2026

    Abstract Motor imbalance is a critical failure mode in rotating machinery, potentially causing severe equipment damage if undetected. Traditional vibration-based diagnostic methods rely on direct sensor contact, leading to installation challenges and measurement artifacts that can compromise accuracy. This study presents a novel radar-based framework for non-contact motor imbalance detection using 24 GHz continuous-wave radar. A dataset of 1802 experimental trials was sourced, covering four imbalance levels (0, 10, 20, 30 g) across varying motor speeds (500–1500 rpm) and load torques (0–3 Nm). Dual-channel in-phase and quadrature radar signals were captured at 10,000 samples per second… More >

  • Open Access

    REVIEW

    Salivary Biomarkers and Their Link to Oncogenic Signaling Pathways in Oral Squamous Cell Carcinoma: Diagnostic and Translational Perspectives in a Narrative Review

    Wen-Shou Tan1,#, Hsuan Kuo2,#, Chang-Ge Jiang1, Mei-Han Lu1, Yi-He Lu1, Yung-Li Wang1, Ching-Shuen Wang1, Thi Thuy Tien Vo3, I-Ta Lee1,*

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070871 - 30 December 2025

    Abstract This narrative review examines recent advances in salivary biomarkers for oral squamous cell carcinoma (OSCC), a major subtype of oral cancer with persistently low five-year survival rates due to delayed diagnosis. Saliva has emerged as a noninvasive diagnostic medium capable of reflecting both local tumor activity and systemic physiological changes. Various salivary biomarkers, including microRNAs, cytokines, proteins, metabolites, and exosomes, have been linked to oncogenic signaling pathways involved in tumor progression, immune modulation, and therapeutic resistance. Advances in quantitative polymerase chain reaction, mass spectrometry, and next-generation sequencing have enabled comprehensive biomarker profiling, while point-of-care detection More >

  • Open Access

    PROCEEDINGS

    In-Vivo Chromophore Characterization of the Human Skin

    Qiaoyun Yu, Shibin Wang*, Zhiyong Wang, Chuanwei Li, Linan Li

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.34, No.1, pp. 1-1, 2025, DOI:10.32604/icces.2025.011080

    Abstract The concentration of chromophores in the human skin provides crucial information for non-invasive skin diagnostics, particularly in clinical and dermatological applications [1,2]. However, only a few studies have reported chromophore concentration measurements at different skin depths [3,4]. This paper introduces a method for the tomographic measurement of skin chromophore concentrations using reflectance spectra. By considering the variations in hemoglobin content at different skin depths, we developed a dual-band skin reflectance spectral model and employed a hyperspectral camera to measure the in vivo spectral reflectance of the human skin. Chromophores including oxyhemoglobin, deoxyhemoglobin, blood oxygen, and melanin… More >

  • Open Access

    CASE REPORT

    Successful treatment of rare vaso-vesical fistula with minimally invasive measures despite prior history of radiotherapy: a case report

    Jordan L. Mendelson1,*, Jordan Kassab1, Phillip Westbrook1, Katie Yang2, Anthony Corcoran1

    Canadian Journal of Urology, Vol.32, No.6, pp. 673-676, 2025, DOI:10.32604/cju.2025.063770 - 30 December 2025

    Abstract Stereotactic body radiotherapy (SBRT) for prostate cancer is a generally well-tolerated treatment but can rarely lead to complications such as fistula formation. We report a 69-year-old male on maintenance ibrutinib for chronic lymphocytic leukemia who developed a fistula between his bladder and vas deferens in the setting of ascending scrotal infection. Despite his prior history of SBRT, the fistula was successfully treated with minimally invasive measures. A combination of abscess debridement, urinary diversion, and broad-spectrum antibiotics helped to achieve fistula resolution. The unique presentation described herein highlights the importance of early aggressive intervention for source More >

  • Open Access

    ARTICLE

    Cryotherapy for non-muscle invasive bladder cancer—preliminary results in an animal model

    Azik Hoffman1,2,*, Eyal Kochavi3, Gilad E. Amiel1,2

    Canadian Journal of Urology, Vol.32, No.5, pp. 423-432, 2025, DOI:10.32604/cju.2025.064740 - 30 October 2025

    Abstract Objectives: Initial treatment for Non-Muscle Invasive Bladder Cancer (NMIBC) has remained mostly unchanged in recent decades. Cryotherapy with CO2 has been commonly used in medicine for many years. In this study, we present the results of a pre-clinical study aimed at developing a novel cryoablation device to treat superficial low-grade bladder lesions. Methods: Following initial technical and developmental studies, a rigid cryotherapy device was developed. A technical and efficacy assessment was conducted utilizing the porcine model. Overall, twenty-six ablation areas (up to four per animal) were evaluated. Following an initial routine cystoscopy, the bladder irrigation medium… More >

  • Open Access

    ARTICLE

    Noninvasive Hemoglobin Estimation with Adaptive Lightweight Convolutional Neural Network Using Wearable PPG

    Florentin Smarandache1, Saleh I. Alzahrani2, Sulaiman Al Amro3, Ijaz Ahmad4, Mubashir Ali5,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 3715-3735, 2025, DOI:10.32604/cmes.2025.068736 - 30 September 2025

    Abstract Hemoglobin is a vital protein in red blood cells responsible for transporting oxygen throughout the body. Its accurate measurement is crucial for diagnosing and managing conditions such as anemia and diabetes, where abnormal hemoglobin levels can indicate significant health issues. Traditional methods for hemoglobin measurement are invasive, causing pain, risk of infection, and are less convenient for frequent monitoring. PPG is a transformative technology in wearable healthcare for noninvasive monitoring and widely explored for blood pressure, sleep, blood glucose, and stress analysis. In this work, we propose a hemoglobin estimation method using an adaptive lightweight… More >

  • Open Access

    ARTICLE

    Species Number of Invasive Plants Negatively Regulates Carbon Contents, Enzyme Activities, and Bacterial Alpha Diversity in Soil

    Qi Chen1,2, Yizhuo Du1, Yingsheng Liu1, Yue Li1, Chuang Li1, Zhelun Xu1,3, Congyan Wang1,4,5,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2873-2891, 2025, DOI:10.32604/phyton.2025.065970 - 30 September 2025

    Abstract The leaves of multiple invasive plants can coexist and intermingle within the same environment. As species number of invasive plants increases, variations may occur in decomposition processes of invasive plants, soil nutrient contents, soil enzyme activities, and soil microbial community structure. Existing progress have predominantly focused on the ecological effects of one species of invasive plant compared to native species, with limited attention paid to the ecological effects of multiple invasive plants compared to one species of invasive plant. This study aimed to determine the differences in the effects of mono- and co-decomposition of four… More >

  • Open Access

    ARTICLE

    Survival outcomes with pelvic node dissection after partial cystectomy among octogenarians with muscle-invasive bladder cancer

    Arjun Pon Avudaiappan*, Pushan Prabhakar, Hannah Baker, Mukesh K. Roy, Manuel Ozambela Jr, Christopher Gomez, Murugesan Manoharan

    Canadian Journal of Urology, Vol.32, No.3, pp. 137-143, 2025, DOI:10.32604/cju.2025.064725 - 27 June 2025

    Abstract Introduction: Radical cystectomy with pelvic node dissection remains the standard of care for muscle-invasive bladder carcinoma (MIBC); however, there is a growing interest in bladder preservation alternatives among the elderly population. Guidelines indicate that partial cystectomy (PC) combined with pelvic node dissection (LND) can be considered as an alternative in carefully selected individuals. Using the National Cancer Database, we analyzed the overall survival (OS) between PC with and without LND among octogenarians. Methods: We identified octogenarians with localized muscle-invasive bladder carcinoma (cT2-3N0M0) and urothelial histology who underwent PC with or without LND between 2004 and… More >

  • Open Access

    ARTICLE

    Role of J stent as a minimally invasive treatment option for ureteropelvic junction obstruction

    Murat Yavuz Koparal1, Burak Elmas2,*, Serhat Gurocak1, Cihat Aytekin1, Mustafa Ozgur Tan1

    Canadian Journal of Urology, Vol.32, No.3, pp. 199-207, 2025, DOI:10.32604/cju.2025.063616 - 27 June 2025

    Abstract Aim: The aim of this study was to investigate the factors affecting treatment success in children that got either pyeloplasty or J stent placement in ureteropelvic junction obstruction (UPJO). Patients and Methods: The study comprised 126 patients who either J stent placement or pyeloplasty performed by the same physician for UPJO from 2012 to 2022. The criteria for surgical intervention adhered to the European Association of Urology (EAU) recommendations. Symptomatic patients with verified obstruction, with a split renal function (SRF) over 40%, low-grade hydronephrosis (Society of Fetal Urology grade 2), and an obstructive segment measuring less… More >

  • Open Access

    ARTICLE

    Intradermal priming to intravesical Bacillus Calmette-Guérin in non-muscle invasive bladder cancer: A translational research and phase I clinical trial

    LUCIANA SABOYA1,2, KEINI BUOSI1, TIAGO SILVA2, ELAINE CANDIDO1, JOSIANE MORARI3, LICIO A. VELLOSO3, SHAHROKH F. SHARIAT4,5,6,7, MARCUS V. SADI2, LEONARDO O. REIS1,8,9,*

    Oncology Research, Vol.33, No.6, pp. 1495-1503, 2025, DOI:10.32604/or.2025.061812 - 29 May 2025

    Abstract Objective: To determine the safety and the role of modulating cytokines and proteases in the immune response to intravesical Bacillus Calmette-Guérin (BCG) when primed with systemic intradermal BCG. Methods: Phase 1 and mechanistic longitudinal, prospective, single-blind randomized study (NCT04806178). Twenty-one non-muscle invasive urothelial bladder cancer patients undergoing intravesical adjuvant BCG after transurethral resection of bladder tumor (TURBT) in a teaching hospital between September 2021 and April 2023 were randomized to 0.1 mL of intradermal BCG vaccine or placebo (0.9% saline) administered 15 days before the start of intravesical BCG therapy. Blood samples were evaluated mechanistically… More >

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