Hailing Yang¹, Suoping Li^1,2,*, Duo Peng²

CMC-Computers, Materials & Continua, Vol.79, No.3, pp. 5273-5294, 2024, DOI:10.32604/cmc.2024.050869

Abstract To address the problems of network congestion and spectrum resources shortage in multi-user large-scale scenarios, this paper proposes a twice random access OFDMA-NOMA-RA protocol combining the advantages of orthogonal frequency division multiple access (OFDMA) and non-orthogonal multiple access (NOMA). The idea of this protocol is that OFMDA is used to divide the entire frequency field into multiple orthogonal resource units (RUs), and NOMA is used on each RU to enable more users to access the channel and improve spectrum efficiency. Based on the protocol designed in this paper, in the case of imperfect successive interference… More >

Gaowu Hu^*, Ye Xu^*, Wenquan Chen^*, Jiandong Wang^†, Chunying Zhao^†1, Ming Wang^*1

Oncology Research, Vol.24, No.6, pp. 455-461, 2016, DOI:10.3727/096504016X14685034103635

Abstract Breast cancer is a highly prevalent disease affecting women. The association of IQ motif containing GTPaseactivating protein 3 (IQGAP3) and breast cancer is poorly defined. Here we reported that IQGAP3 is a key regulator of cell proliferation and metastasis during breast cancer progression. The expression of IQGAP3 was significantly increased in breast tissues compared to nontumor tissues at both protein and mRNA levels. Furthermore, IQGAP3 had a high expression level in ZR-75-30 and BT474 compared to other breast cancer cell lines. Depletion of IQGAP3 through RNA interference in ZR-75-30 and BT474 significantly inhibited cell proliferation. More >

Qian Li, Jing Jin, Jianghui Liu, Liqun Wang, Yutong He

Oncology Research, Vol.24, No.3, pp. 205-214, 2016, DOI:10.3727/096504016X14648701447896

Abstract We recently found that SLC39A5 (ZIP5), a zinc transporter, is overexpressed in esophageal cancer. Downregulation of ZIP5 inhibited the proliferation, migration, and invasion of the esophageal cancer cell line KYSE170 in vitro. In this study, we found that downregulation of SLC39A5 (ZIP5) by interference resulted in a significant reduction in esophageal cancer tumor volume and weight in vivo. COX2 (cyclooxygenase 2) expression was decreased and E-cadherin expression was increased in the KYSE170K xenografts, which was caused by the downregulation of ZIP5. However, we did not find that the downregulation of ZIP5 caused a change in More >

Jianpeng Liu^*, Wei Li^†, Shunshun Liu^*, Xu Zheng^*, Lin Shi^*, Weitao Zhang^*, Hongfa Yang^*

Oncology Research, Vol.25, No.2, pp. 225-232, 2017, DOI:10.3727/096504016X14732772150587

Abstract Collagen triple helix repeat containing 1 (CTHRC1), an extracellular matrix-related protein, has been found to be upregulated in many solid tumors and contributes to tumorigenesis. We found that CTHRC1 is overexpressed in glioblastoma tissues and cells. By using the technique of RNA interference, the expression of CTHRC1 in the human glioblastoma U-87MG cell line was downregulated, and the proliferation and migration of U-87MG cells were examined. The results showed that the knockdown of CTHRC1 exerts inhibitory effects on the proliferation and migration ability of U-87MG cells. Knockdown of CTHRC1 expression in U-87MG cells resulted in More >

Jianping Xu, Liguo Sun, Wei Sun, Jianhai Tian, Huaiyuan Guo

Oncology Research, Vol.26, No.7, pp. 997-1003, 2018, DOI:10.3727/096504017X15140544654946

Abstract To investigate the effect of Kim-1 on 786-0 cells in vivo and in vitro, several experiments such as quantitative real-time PCR, Western blot, MTT, colony formation, and flow cytometry were performed to evaluate the biological behavior of 786-0 cells treated with Kim-1 siRNA. Furthermore, the tumor xenograft model was applied to BALB/c nude mice to assess the effect of Kim-1 silencing. Lentivirus-mediated RNAi effectively silenced Kim-1 in 786-0 cells. Kim-1 knockdown significantly inhibited the proliferation and colony formation ability of 786-0 cells (p < 0.01). The cell cycle of 786-0 cells was arrested in the G₀/G₁ phase (p < More >

Chaozhi Cai^*, Xiaoyu Guo, Yingfang Xue, Jianhua Ren

Structural Durability & Health Monitoring, Vol.18, No.3, pp. 321-339, 2024, DOI:10.32604/sdhm.2024.045831

Abstract Bleachers play a crucial role in practical engineering applications, and any damage incurred during their operation poses a significant threat to the safety of both life and property. Consequently, it becomes imperative to conduct damage diagnosis and health monitoring of bleachers. The intricate structure of bleachers, the varied types of potential damage, and the presence of similar vibration data in adjacent locations make it challenging to achieve satisfactory diagnosis accuracy through traditional time-frequency analysis methods. Furthermore, field environmental noise can adversely impact the accuracy of bleacher damage diagnosis. To enhance the accuracy and anti-noise capabilities… More > Graphic Abstract

Nguyen Vu Anh Duy, Nguyen Le Thai, Nguyen Huu Tho^*

Intelligent Automation & Soft Computing, Vol.39, No.1, pp. 15-31, 2024, DOI:10.32604/iasc.2024.038272

Abstract In this paper, we consider a multi-crane scheduling problem in rail stations because their operations directly influence the throughput of the rail stations. In particular, the job is not only assigned to cranes but also the job sequencing is implemented for each crane to minimize the makespan of cranes. A dual cycle of cranes is used to minimize the number of working cycles of cranes. The rail crane scheduling problems in this study are based on the movement of containers. We consider not only the gantry moves, but also the trolley moves as well as More >

DAOLUN YU¹, DEYONG SHE², KAI GE¹, LEI YANG¹, RUINA ZHAN¹, SHAN LU^3,*, YAFEI CAI^4,*

BIOCELL, Vol.48, No.1, pp. 139-147, 2024, DOI:10.32604/biocell.2023.045884

Abstract Background: SMAD family proteins (SMADs) are crucial transcription factors downstream of transforming growth factor beta (TGF-ß)/SMAD signaling pathways that have been reported to play a pivotal role in mammalian reproduction. However, the role of SMAD family member 8 (SMAD8, also known as SMAD9), a member of the SMAD family, in mammalian reproduction remains unclear. Methods: We employed RNA interference techniques to knock down Smad8 expression in mouse granulosa cells (GCs) to investigate the effects of Smad8 on GC growth and steroidogenesis. Results: Our findings revealed a significant decrease in the proliferative capacity and a substantial increase in… More >

Diguang Gong¹, Junbin Chen¹, Cheng Cheng², Yuanyuan Kou^2,*

Energy Engineering, Vol.121, No.2, pp. 425-437, 2024, DOI:10.32604/ee.2023.030196

Abstract Horizontal well-stimulation is the key to unconventional resource exploration and development. The development mode of the well plant helps increase the stimulated reservoir volume. Nevertheless, fracture interference between wells reduces the fracturing effect. Here, a 2D hydro-mechanical coupling model describing hydraulic fracture (HF) propagation is established with the extended finite element method, and the effects of several factors on HF propagation during multiple wells fracturing are analyzed. The results show that with an increase in elastic modulus, horizontal principal stress difference and injection fluid displacement, the total fracture area and the reservoir stimulation efficiency are More >

Kaleem Arshid^1,*, Jianbiao Zhang¹, Muhammad Yaqub¹, Mohammad Daud Awan², Habiba Ijaz³, Imran Shabir Chuhan⁴

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 2631-2647, 2023, DOI:10.32604/cmc.2023.035735

Abstract Channel assignment has emerged as an essential study subject in Cognitive Radio-based Wireless Mesh Networks (CR-WMN). In an era of alarming increase in Multi-Radio Multi-Channel (MRMC) network expansion interference is decreased and network throughput is significantly increased when non-overlapping or partially overlapping channels are correctly integrated. Because of its ad hoc behavior, dynamic channel assignment outperforms static channel assignment. Interference reduces network throughput in the CR-WMN. As a result, there is an extensive research gap for an algorithm that dynamically distributes channels while accounting for all types of interference. This work presents a method for More >