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  • Open Access

    REVIEW

    Insights on Bmi-1 therapeutic targeting in head and neck cancers

    JESSIE REYES-CARMONA*

    Oncology Research, Vol.33, No.2, pp. 301-307, 2025, DOI:10.32604/or.2024.053764 - 16 January 2025

    Abstract The B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) protein of the polycomb complex is an essential mediator of the epigenetic transcriptional silencing by the chromatin structure. It has been reported to be crucial for homeostasis of the stem cells and tumorigenesis. Though years of investigation have clarified Bmi-1’s transcriptional regulation, post-translational modifications, and functions in controlling cellular bioenergetics, pathologies, and DNA damage response, the full potential of this protein with so many diverse roles are still unfulfilled. Bmi-1 is overexpressed in many human malignancies. Unraveling the Bmi-1’s precise functional role in head and neck… More >

  • Open Access

    ARTICLE

    Production of Light Fraction-Based Pyrolytic Fuel from Spirulina platensis Microalgae Using Various Low-Cost Natural Catalysts and Insertion

    Indra Mamad Gandidi1,2,*, Sukarni Sukarni3,4, Avita Ayu Permanasari3, Purnami Purnami5, Tuan Amran Tuan Abdullah6, Anwar Johari6, Nugroho Agung Pambudi7,*

    Energy Engineering, Vol.121, No.12, pp. 3635-3648, 2024, DOI:10.32604/ee.2024.054943 - 22 November 2024

    Abstract The use of catalysts has significantly enhanced the yield and quality of in-situ pyrolysis products. However, there is a lack of understanding regarding pyrolysis approaches that utilize several low-cost natural catalysts (LCC) and their placement within the reactor. Therefore, this study aims to examine the effects of various LCC on the in-situ pyrolysis of spirulina platensis microalgae (SPM) and investigate the impact of different types of catalysts. We employed LCC such as zeolite, dolomite, kaolin, and activated carbon, with both layered and uniformly mixed LCC-SPM placements. Each experiment was conducted at a constant temperature of 500°C… More > Graphic Abstract

    Production of Light Fraction-Based Pyrolytic Fuel from <i>Spirulina platensis</i> Microalgae Using Various Low-Cost Natural Catalysts and Insertion

  • Open Access

    ARTICLE

    Heat Transfer Enhancement of the Absorber Tube in a Parabolic Trough Solar Collector through the Insertion of Novel Cylindrical Turbulators

    Yasser Jebbar1,2,*, Fadhil Fluiful2, Wisam Khudhayer3

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.6, pp. 1279-1297, 2024, DOI:10.32604/fdmp.2024.050753 - 27 June 2024

    Abstract This study includes an experimental and numerical analysis of the performances of a parabolic trough collector (PTC) with and without cylindrical turbulators. The PTC is designed with dimensions of 2.00 m in length and 1.00 m in width. The related reflector is made of lined sheets of aluminum, and the tubes are made of stainless steel used for the absorption of heat. They have an outer diameter of 0.051 m and a wall thickness of 0.002 m. Water, used as a heat transfer fluid (HTF), flows through the absorber tube at a mass flow rate… More >

  • Open Access

    ARTICLE

    Appropriate Combination of Crossover Operator and Mutation Operator in Genetic Algorithms for the Travelling Salesman Problem

    Zakir Hussain Ahmed1,*, Habibollah Haron2, Abdullah Al-Tameem3

    CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2399-2425, 2024, DOI:10.32604/cmc.2024.049704 - 15 May 2024

    Abstract Genetic algorithms (GAs) are very good metaheuristic algorithms that are suitable for solving NP-hard combinatorial optimization problems. A simple GA begins with a set of solutions represented by a population of chromosomes and then uses the idea of survival of the fittest in the selection process to select some fitter chromosomes. It uses a crossover operator to create better offspring chromosomes and thus, converges the population. Also, it uses a mutation operator to explore the unexplored areas by the crossover operator, and thus, diversifies the GA search space. A combination of crossover and mutation operators… More >

  • Open Access

    ARTICLE

    A Novel Insertion Solution for the Travelling Salesman Problem

    Emmanuel Oluwatobi Asani1,2,3, Aderemi Elisha Okeyinka4, Sunday Adeola Ajagbe5,6, Ayodele Ariyo Adebiyi1, Roseline Oluwaseun Ogundokun1,2,7,*, Temitope Samson Adekunle8, Pragasen Mudali5, Matthew Olusegun Adigun5

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1581-1597, 2024, DOI:10.32604/cmc.2024.047898 - 25 April 2024

    Abstract The study presents the Half Max Insertion Heuristic (HMIH) as a novel approach to solving the Travelling Salesman Problem (TSP). The goal is to outperform existing techniques such as the Farthest Insertion Heuristic (FIH) and Nearest Neighbour Heuristic (NNH). The paper discusses the limitations of current construction tour heuristics, focusing particularly on the significant margin of error in FIH. It then proposes HMIH as an alternative that minimizes the increase in tour distance and includes more nodes. HMIH improves tour quality by starting with an initial tour consisting of a ‘minimum’ polygon and iteratively adding… More >

  • Open Access

    ARTICLE

    Synthesis and mechanism of MoS2 and graphene oxide insertion in porous multi metal ion modified MnO2 nanorods for dye degradation

    R. Jothiramalingam*, H. Al-Lohedan, D. M. Al-Dhayan, A. Karami

    Chalcogenide Letters, Vol.20, No.12, pp. 891-901, 2023, DOI:10.15251/CL.2023.2012.891

    Abstract Layered structure transition metal chalcogenide compound’s such as Molybdenum sulfide (MoS2) deposition in micro/meso porous architecture of MnO2 could provide hybrid inter esting features. Multivalent MnO2 is an attractive low cost and toxic free catalytic materi al for oxidation reaction and electrochemical applications. Non-ionic surfactant implica tion in mesoporous metal ion modified MnO2 by deposition of metal chalcogenide is an ef fective composite for dye degradation applications. The low-cost pre-cursor makes it at tractive for large-scale production at industrial scale. Hence, in the present study deals with exploit the mechanism of metal chalcogenide and graphene oxide insertion More >

  • Open Access

    ARTICLE

    Cost-effectiveness analysis of arterial catheter insertion on robotic-assisted laparoscopic prostatectomy

    Rogelio Valdez1,2, Johnathan Drevik3, Megan Prunty1,2, Ilaha Isali1,2, Mohit Sindhani4, Lee Ponsky1,2, Alberto Castro Bigalli5, David Chen5, Kirtishri Mishra1,2, Alexander Kutikov5, Adam Calaway1,2, Laura Bukavina1,5

    Canadian Journal of Urology, Vol.30, No.2, pp. 11495-11501, 2023

    Abstract Introduction: To evaluate the utility, outcomes, and cost of arterial line placement in a single institution cohort of patients undergoing robotic-assisted laparoscopic prostatectomy (RALP).
    Materials and methods: A retrospective chart review was performed at a large tertiary care center from July 2018 through January 2021. Hospital costs and cost-effective analysis was performed on patients with and without arterial line placement. Means with standard deviations were used to report continuous variables, while numbers and percentages were utilized to describe categorical variables. T-tests and Chi-square tests compared categorical and continuous variables across study cohorts, respectively. Multivariable analyses were used… More >

  • Open Access

    ARTICLE

    Mode of Operation for Modification, Insertion, and Deletion of Encrypted Data

    Taek-Young Youn1, Nam-Su Jho2,*

    CMC-Computers, Materials & Continua, Vol.73, No.1, pp. 151-164, 2022, DOI:10.32604/cmc.2022.026653 - 18 May 2022

    Abstract

    Due to the development of 5G communication, many aspects of information technology (IT) services are changing. With the development of communication technologies such as 5G, it has become possible to provide IT services that were difficult to provide in the past. One of the services made possible through this change is cloud-based collaboration. In order to support secure collaboration over cloud, encryption technology to securely manage dynamic data is essential. However, since the existing encryption technology is not suitable for encryption of dynamic data, a new technology that can provide encryption for dynamic data is required

    More >

  • Open Access

    ARTICLE

    An Animated GIF Steganography Using Variable Block Partition Scheme

    Maram Abdullah M. Alyahya1, Arshiya S. Ansari1,*, Mohammad Sajid Mohammadi2

    Computer Systems Science and Engineering, Vol.43, No.3, pp. 897-914, 2022, DOI:10.32604/csse.2022.023904 - 09 May 2022

    Abstract The paper presents a novel Graphics Interchange Format (GIF) Steganography system. The algorithm uses an animated (GIF) file format video to apply on, a secured and variable image partition scheme for data embedding. The secret data could be any character text, any image, an audio file, or a video file; that is converted in the form of bits. The proposed method uses a variable partition scheme structure for data embedding in the (GIF) file format video. The algorithm estimates the capacity of the cover (GIF) image frames to embed data bits. Our method built variable… More >

  • Open Access

    ARTICLE

    Capacitive Coupled Wide-Notch Stepped Impedance Narrow-Band Bandpass Filter for WiMax Application

    A. Kayalvizhi*, G. Sankara Malliga

    Computer Systems Science and Engineering, Vol.43, No.2, pp. 501-514, 2022, DOI:10.32604/csse.2022.022855 - 20 April 2022

    Abstract The development of wireless communication standards necessitates optimal filter design for the selection of appropriate bands of frequencies. In this work, a compact in size pair of parallel coupled symmetric stepped impedance-based resonator is designed with supporting to the WiMAX communication standards. The coupled resonator is tuned to allow the frequency band between 3.4 GHz and 3.8 GHz, which is centered at 3.6 GHz. A parasitic effect of capacitively coupled feed structure is used for exciting the two symmetrical stepped impedance resonators. The bandwidth and selectivity of the filter are enhanced with the change of characteristic impedances and… More >

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