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  • Open Access

    ARTICLE

    P2RX1 Influences the Prognosis of Ph+/Ph-Like ALL through Energy and Calcium Metabolism

    Xiangmei Ye1,2,3, Baoyi Yang4, Xin Zhang5, Luyuan Yang1, Likun Zhang5, Qin Ren1, Xiaobing Li1, Leiguang Feng1, Lanlan Wei3,6,7,*, Peng Song1, Yuqing Ye8, Xin Lian9, Yujuan Gao9, Haidi Tang1, Zhiyu Liu1

    Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.068814 - 30 December 2025

    Abstract Objectives: Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia and Philadelphia-like B-cell acute lymphoblastic leukemia (Ph+/Ph-like ALL) constitute the majority of relapsed/refractory B-ALL (R/R B-ALL) cases, highlighting an urgent need to discover new therapeutic targets. This study aims to elucidate the mechanisms underlying poor prognosis in Ph+/Ph-like ALL through transcriptome sequencing and functional cytological assays, with the goal of informing new clinical treatment strategies. Results: Transcriptomic analysis of Ph+/Ph-like ALL patients revealed that low expression of P2X Purinoceptor 1 (P2RX1) was associated with unfavorable outcomes. Specifically, patients with poor prognosis and low P2RX1 expression exhibited downregulation of… More >

  • Open Access

    ARTICLE

    Influence of Sulfonated Chitosan on Conductivity of Sulfonated Polyether Ether Ketone (SPEEK) at Room Temperature

    Aina Aqilah Mohd Rizal1, Oskar Hasdinor Hassan2, Nor Kartini Jaafar1,2, Masnawi Mustaffa1, Mohd Tajudin Mohd Ali1,*, Ajis Lepit3, Nazli Ahmad Aini1,2,*

    Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.071726 - 27 December 2025

    Abstract Proton exchange membrane (PEM) is an integral component in fuel cells which enables proton transport for efficient energy conversion. Sulfonated Polyether Ether Ketone (SPEEK) has emerged as a cost-effective option with non-fluorinated aromatic backbones for Proton Exchange Membrane Fuel Cell (PEMFC) applications, even though it exhibits lower proton conductivity compared to Nafion. This work aims to study the influence of Sulfonated Chitosan (SCS) concentrations on proton conductivity of SPEEK-based PEM at room temperature. SPEEK was synthesized using a sulfonation process with concentrated sulfuric acid at room temperature. SCS was synthesized via reflux of CS and… More > Graphic Abstract

    Influence of Sulfonated Chitosan on Conductivity of Sulfonated Polyether Ether Ketone (SPEEK) at Room Temperature

  • Open Access

    ARTICLE

    Influence of Honey on Structural, Morphology and Thermal Behavior of Zein-Based Polymer Systems

    Nurrul Asyiqin K. Shamsuri1, Shujahadeen B. Aziz2, Siti Nadiah Halim3, Hashlina Rusdi4, Mohd Fakhrul Zamani Kadir1,5,*

    Journal of Polymer Materials, Vol.42, No.4, pp. 1111-1123, 2025, DOI:10.32604/jpm.2025.070939 - 26 December 2025

    Abstract This study investigates the effects of honey concentration on the crystallinity, morphology, and thermal behavior of zein-based polymer systems, aiming to assess honey’s role as a natural plasticizer. Fourier transform infrared spectroscopy (FTIR) analysis confirmed the presence of strong intermolecular interactions and hydrogen bonding between zein and honey, indicating good miscibility. X-ray diffraction (XRD) patterns revealed a significant reduction in crystallinity with increasing honey concentration up to 25 wt.%, with the ZH5 (75 wt.% zein-25 wt.% honey) sample exhibiting the smallest crystallite size (4.23 nm), suggesting enhanced amorphous character suitable for ionic mobility. Field emission… More >

  • Open Access

    ARTICLE

    Finite Element Analysis of the Influence of End Grouting Defects in Grouted Sleeve on the Structural Performance of Precast Reinforced Concrete Columns

    Shuoting Xiao1,*, Nikita Igorevich Fomin1, Kirill Anatolyevich Khvostunkov2, Chong Liu1

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 2821-2847, 2025, DOI:10.32604/cmes.2025.071961 - 23 December 2025

    Abstract Precast concrete structures have gained popularity due to their advantages. However, the seismic performance of their connection joints remains an area of ongoing research and improvement. Grouted Sleeve Connection (GSC) offers a solution for connecting reinforcements in precast components, but their vulnerability to internal defects, such as construction errors and material variability, can significantly impact performance. This article presents a finite element analysis (FEA) to evaluate the impact of internal grouting defects in GSC on the structural performance of precast reinforced concrete columns. Four finite element models representing GSC with varying degrees of defects were… More > Graphic Abstract

    Finite Element Analysis of the Influence of End Grouting Defects in Grouted Sleeve on the Structural Performance of Precast Reinforced Concrete Columns

  • Open Access

    ARTICLE

    Influence of neodymium doping on radiation shielding properties of yttrium lead borotellurite glass system

    M. R. S. Nasuhaa,*, H. Azhanb,c, L. Hasnimulyatic, W. A. W. Razalic, Y. Norihanc

    Chalcogenide Letters, Vol.22, No.1, pp. 23-31, 2025, DOI:10.15251/CL.2025.221.23

    Abstract The need for effective shielding materials has grown as radiation-based technologies have been more widely used. Glasses doped with rare earth elements like neodymium oxide, are promising candidates due to their enhanced radiation attenuation properties. Using Phy-X software, this research examines how neodymium oxide doping affects the shielding properties of yttrium lead borotellurite glass. X-ray diffraction confirmed the amorphous structure, while density measurements showed increased density with neodymium oxide addition. The Phy-X software calculated radiation shielding parameters for gamma energies from 10⁻³ to 10 MeV. The results demonstrate that neodymium oxide improves gamma irradiation attenuation and More >

  • Open Access

    ARTICLE

    Influence of Ag content on direct current conductivity of Agx(As2(Te0.5Se0.5)3)100-x system

    G. R. Štrbaca,*, O. Bošákb, D. Štrbacc, R. Vigia, M. Kublihab, S. Minárikb

    Chalcogenide Letters, Vol.22, No.5, pp. 481-491, 2025, DOI:10.15251/CL.2025.225.481

    Abstract The temperature dependence of direct current (DC) conductivity, silver content, and the presence of crystalline phases in amorphous and annealed chalcogenides from the Agx(As2(Te0.5Se0.5)3)100-x system was investigated. Amorphous samples exhibited semiconducting behavior, with conductivity increase as the silver content raised. This increase was primarily attributed to electron transitions into delocalized states from states localized near the Fermi level. Percolation behavior in conductivity was observed in the samples containing 7 at.% or more silver. For annealed samples with silver content below 9 at.%, temperature-independent DC conductivity was identified, accompanied by a decrease in conductivity as the silver More >

  • Open Access

    ARTICLE

    Influence of heat treatment on microwave dielectric properties of erbium doped borotellurite glass ceramics

    S. Othmana, Y. H. Luab, E. S. Sazalia,, Y. S. Yapb,, R. Hisamc

    Chalcogenide Letters, Vol.22, No.5, pp. 451-459, 2025, DOI:10.15251/CL.2025.225.451

    Abstract High-performance glass-ceramics are increasingly explored for their suitability in high-frequency dielectric applications, presenting a significant challenge in materials science. A primary focus has been allocated to investigating borotellurite glasses operating at frequencies below 15 MHz. Borotellurite glasses with the composition 69TeO-10BO3-10PbO-10ZnO-1ErO3 were fabricated via the melt-quenching method. This study examines the effects of heat treatment durations (1–24 hours) on these glasses. Variations in density, molar volume, structure, and dielectric properties were attributed to changes in non-bridging oxygen bonding resulting from the heat treatments. X-ray diffraction analysis confirmed the amorphous nature of the as-quenched glass. Morphological changes More >

  • Open Access

    ARTICLE

    Higher sensitive influence on Cu2S: Sb and Cu2S: Al heterojunction for application photodetectors

    H. K. Hassuna,*, B. H. Husseina, B. K. H. Al-Maiyalya, R. H. Athaba, Y. K. H. Moussab

    Chalcogenide Letters, Vol.22, No.6, pp. 541-550, 2025, DOI:10.15251/CL.2025.226.541

    Abstract Photoconductive possessions through the highly sensitive and responsive in lower applications apply voltages with a charge that effect the product for the photodetector utilizing Copper Sulfide was effective to fabricate and deposit by the means of thermal evaporation techniques following by the heat treatment with applications as the visible photodetector was described. Effects of doping to the antimony and aluminum on photo detectors property were estimated to be below illumination by the utilization of different power densities. The structure with the surface morphology properties was studied by XRD and AFM techniques, a clear effect of More >

  • Open Access

    ARTICLE

    Influence of processing parameters on physiochemical properties of cadmium sulfide nanoparticles

    S. R. Ahmeda,*, M. V. V. K. S. Prasada, K. Keerthivasanb

    Chalcogenide Letters, Vol.22, No.9, pp. 765-776, 2025, DOI:10.15251/CL.2025.229.765

    Abstract This study focuses on optimizing practical synthesis to produce ultrafine CdS nanoparticles. Three separate chemical synthesis processes, namely microwave, wetchemical, and sonication methods, are used to generate CdS nanoparticles. Moringa oleifera leaf extract employed green syntheses of CdS nanoparticles are also performed for additional discussions. The generated CdS nanoparticles were subjected to a comparative assessment to identify the most effective processing method for synthesizing CdS nanoparticles. Even though the processing parameters were altered over their synthesis, the hexagonal structure was retained in the CdS nanoparticles. The observed results of CdS nanoparticles from XRD, SEM/EDX, and More >

  • Open Access

    ARTICLE

    Tensoelectric properties of (BixSb1-x)2Te3 films under the influence of a microwave field

    R. U. Siddikov*, Kh. M. Sulaymonov, N. Kh. Yuldashev

    Chalcogenide Letters, Vol.22, No.10, pp. 855-862, 2025, DOI:10.15251/CL.2025.2210.855

    Abstract This paper presents the results of an experimental study of the tens metric and dielectric properties of polycrystalline (BixSb1-x)2Te3 films in the temperature range of 280−480 K and at microwave frequencies. The temperature dependences of the specific conductivity, impedance, and permittivity under the action of uniaxial static deformation are analyzed. The deformation phenomena detected in polycrystalline films under the action of a microwave field are qualitatively interpreted based on the effective medium theory. More >

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