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  • Open Access

    CASE REPORT

    Stubborn Hypoxia in Neonates with D-Transposition of the Great Arteries after Arterial Switch Operation: Central Sleep Apnea as the Cause and Potential Indicator of Brain Immaturity

    Camden L. Hebson1,*, Kyle Bliton2, Amr Y. Hammouda1, Kaitlyn Barr3, W. Hampton Gray4, Mohini Gunnett2, Waldemar F. Carlo1

    Congenital Heart Disease, Vol.19, No.2, pp. 185-195, 2024, DOI:10.32604/chd.2024.048871

    Abstract D-transposition of the great arteries (d-TGA) is surgically repaired with the arterial switch operation (ASO) with excellent results, however short and long-term morbidities still develop including neurocognitive delay. Clinically significant central sleep apnea is uncommon in non-premature infants, but when present indicates immature autonomic control of respiration likely due to a neurologic disorder. We report the unanticipated finding of central sleep apnea in four-term neonates with d-TGA after uncomplicated ASO, with the short-term complication of delayed hospital discharge and long-term concerns regarding this early marker of brain immaturity and its hindrance to normal development. Within More >

  • Open Access

    ARTICLE

    Comprehensive Evaluation of Distributed PV Grid-Connected Based on Combined Weighting Weights and TOPSIS-RSR Method

    Yue Yang1, Jiarui Zheng1, Long Cheng1,*, Yongnan Zhu2, Hao Wu2

    Energy Engineering, Vol.121, No.3, pp. 703-728, 2024, DOI:10.32604/ee.2023.044721

    Abstract To effectively quantify the impact of distributed photovoltaic (PV) access on the distribution network, this paper proposes a comprehensive evaluation method of distributed PV grid connection combining subjective and objective combination of assignment and technique for order preference by similarity to an ideal solution (TOPSIS)—rank sum ratio (RSR) (TOPSIS-RSR) method. Based on the traditional distribution network evaluation system, a comprehensive evaluation system has been constructed. It fully considers the new development requirements of distributed PV access on the environmental friendliness and absorptive capacity of the distribution grid and comprehensively reflects the impact of distributed PV… More >

  • Open Access

    ARTICLE

    Bone marrow microRNA-34a is a good indicator for response to treatment in acute myeloid leukemia

    MONA S. ABDELLATEIF1,*, NAGLAA M. HASSAN2, MAHMOUD M. KAMEL2, YOMNA M. EL-MELIGUI2

    Oncology Research, Vol.32, No.3, pp. 577-584, 2024, DOI:10.32604/or.2023.043026

    Abstract Background: microRNA-34a (miR-34a) had been reported to have a diagnostic role in acute myeloid leukemia (AML). However, its value in the bone marrow (BM) of AML patients, in addition to its role in response to therapy is still unclear. The current study was designed to assess the diagnostic, prognostic, and predictive significance of miR-34a in the BM of AML patients. Methods: The miR-34a was assessed in BM aspirate of 82 AML patients in relation to 12 normal control subjects using qRT-PCR. The data were assessed for correlation with the relevant clinical criteria, response to therapy,… More >

  • Open Access

    ARTICLE

    Smart Colorimetric Corn Starch Films Combined with Anthocyanin-Loaded Glutenin-Carboxymethyl Chitosan Nanocomplexes for Freshness Monitoring of Chilled Pork

    Juan Yan1, Wenchao Li1, Xianfang Zhang1, Shisheng Liu2,*

    Journal of Renewable Materials, Vol.12, No.1, pp. 71-87, 2024, DOI:10.32604/jrm.2023.028927

    Abstract In this study, intelligent, pH-responsive colorimetric films were prepared by encapsulating anthocyanins in nanocomplexes prepared from glutenin and carboxymethyl chitosan. These nanocomplexes were added to a corn starch matrix and used in the freshness monitoring of chilled pork. The effects of anthocyanin-loaded nanocomplexes on the physical, structural, and functional characteristics of the films were investigated. The addition of anthocyanin-loaded nanocomplexes increased the tensile strength, elongation at break, hydrophobicity, and light transmittance of the films while decreasing their water vapor permeability. This is because new hydrogen bonds are formed between the film components, resulting in a More >

  • Open Access

    ARTICLE

    Addressing the Issues and Developments Correlated with Envisaged 5G Mobile Technologies: Comprehensive Solutions

    Idrees Sarhan Kocher*

    CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 2205-2223, 2023, DOI:10.32604/cmc.2023.039392

    Abstract Fifth Generation (5G) communications are regarded as the cornerstone to household consumer experience improvements and smart manufacturing revolution from the standpoint of industries' objectives. It is anticipated that Envisaged 5G (E5G) mobile technology would be operational in certain developed countries by 2023. The Internet of Things (IoTs) will transform how humans live when combined with smart and integrated sensing devices, such as in-home sensing devices. Recent research is being carried out all over the world to produce a new technique that can be crucial in the success of the anticipated 5G mobile technology. High output,… More >

  • Open Access

    ARTICLE

    Aryl hydrocarbon receptor nuclear translocator 2 as a prognostic biomarker and immunotherapeutic indicator for clear cell renal cell carcinoma

    RENLONG ZHOU1,2,#, SHUANG LI3,#, XILIN XIAO1,*

    BIOCELL, Vol.47, No.11, pp. 2397-2408, 2023, DOI:10.32604/biocell.2023.030281

    Abstract Background: In many cancer types, aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) has been found to be associated with tumor cell proliferation and prognosis. However, the role of ARNT2 in clear cell renal cell carcinoma (ccRCC) has not been completely elucidated. In this study, the potential role of ARNT2 in ccRCC development was characterized. Methods: A pan-cancer dataset (TCGA-TARGET-GTEx) was accessed from UCSC Xena Data Browser. ARNT2 expression in normal and tumor samples was compared. Univariate Cox regression was performed to evaluate the prognostic value of ARNT2. Single sample gene set enrichment analysis (ssGSEA) was… More >

  • Open Access

    ARTICLE

    Transient receptor potential channels as predictive marker and potential indicator of chemoresistance in colon cancer

    WEI HU1,#, THOMAS WARTMANN2,#, MARCO STRECKER2, ARISTOTELIS PERRAKIS2, ROLAND CRONER2, ARPAD SZALLASI3, WENJIE SHI2,*, ULF D. KAHLERT2,*

    Oncology Research, Vol.32, No.1, pp. 227-239, 2024, DOI:10.32604/or.2023.043053

    Abstract Transient receptor potential (TRP) channels are strongly associated with colon cancer development and progression. This study leveraged a multivariate Cox regression model on publicly available datasets to construct a TRP channels-associated gene signature, with further validation of signature in real world samples from our hospital treated patient samples. Kaplan-Meier (K-M) survival analysis and receiver operating characteristic (ROC) curves were employed to evaluate this gene signature’s predictive accuracy and robustness in both training and testing cohorts, respectively. Additionally, the study utilized the CIBERSORT algorithm and single-sample gene set enrichment analysis to explore the signature’s immune infiltration… More > Graphic Abstract

    Transient receptor potential channels as predictive marker and potential indicator of chemoresistance in colon cancer

  • Open Access

    ARTICLE

    Adversarial Attack-Based Robustness Evaluation for Trustworthy AI

    Eungyu Lee, Yongsoo Lee, Taejin Lee*

    Computer Systems Science and Engineering, Vol.47, No.2, pp. 1919-1935, 2023, DOI:10.32604/csse.2023.039599

    Abstract Artificial Intelligence (AI) technology has been extensively researched in various fields, including the field of malware detection. AI models must be trustworthy to introduce AI systems into critical decision-making and resource protection roles. The problem of robustness to adversarial attacks is a significant barrier to trustworthy AI. Although various adversarial attack and defense methods are actively being studied, there is a lack of research on robustness evaluation metrics that serve as standards for determining whether AI models are safe and reliable against adversarial attacks. An AI model’s robustness level cannot be evaluated by traditional evaluation… More >

  • Open Access

    ARTICLE

    Cyclists’ exposure to air pollution and noise in Mexico City

    Contribution of real-time traffic density indicators integrated into GIS

    Philippe Apparicio1 , Jérémy Gelb1, Paula Negron-Poblete2, Mathieu Carrier1, Stéphanie Potvin1 , Élaine Lesage-Mann1

    Revue Internationale de Géomatique, Vol.30, No.2, pp. 155-179, 2020, DOI:10.3166/rig.2021.00110

    Abstract Air pollution and road traffic noise are two important environmental nuisances that could be harmful to the health and well-being of urban populations. In Mexico City, as in many North American cities, there has been an upsurge in bicycle ridership. However, Mexico City is also well known for having high levels of noise and air pollution. The purpose of this study is threefold: 1) evaluate cyclists’ exposure to air pollution (nitrogen dioxide) and road traffic noise; 2) identify local factors that increase or reduce cyclists’ exposure, in paying particular attention to the type of road… More >

  • Open Access

    ARTICLE

    Predicting Bitcoin Trends Through Machine Learning Using Sentiment Analysis with Technical Indicators

    Hae Sun Jung1, Seon Hong Lee1, Haein Lee1, Jang Hyun Kim2,*

    Computer Systems Science and Engineering, Vol.46, No.2, pp. 2231-2246, 2023, DOI:10.32604/csse.2023.034466

    Abstract Predicting Bitcoin price trends is necessary because they represent the overall trend of the cryptocurrency market. As the history of the Bitcoin market is short and price volatility is high, studies have been conducted on the factors affecting changes in Bitcoin prices. Experiments have been conducted to predict Bitcoin prices using Twitter content. However, the amount of data was limited, and prices were predicted for only a short period (less than two years). In this study, data from Reddit and LexisNexis, covering a period of more than four years, were collected. These data were utilized… More >

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