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  • Open Access

    ARTICLE

    Enhancement of Medical Imaging Technique for Diabetic Retinopathy: Realistic Synthetic Image Generation Using GenAI

    Damodharan Palaniappan1, Tan Kuan Tak2, K. Vijayan3, Balajee Maram4, Pravin R Kshirsagar5, Naim Ahmad6,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 4107-4127, 2025, DOI:10.32604/cmes.2025.073387 - 23 December 2025

    Abstract A phase-aware cross-modal framework is presented that synthesizes UWF_FA from non-invasive UWF_RI for diabetic retinopathy (DR) stratification. A curated cohort of 1198 patients (2915 UWF_RI and 17,854 UWF_FA images) with strict registration quality supports training across three angiographic phases (initial, mid, final). The generator is based on a modified pix2pixHD with an added Gradient Variance Loss to better preserve microvasculature, and is evaluated using MAE, PSNR, SSIM, and MS-SSIM on held-out pairs. Quantitatively, the mid phase achieves the lowest MAE (98.76 ± 42.67), while SSIM remains high across phases. Expert review shows substantial agreement (Cohen’s More >

  • Open Access

    REVIEW

    Importance of Features Selection, Attributes Selection, Challenges and Future Directions for Medical Imaging Data: A Review

    Nazish Naheed1, Muhammad Shaheen1, Sajid Ali Khan1, Mohammed Alawairdhi2,*, Muhammad Attique Khan3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.1, pp. 315-344, 2020, DOI:10.32604/cmes.2020.011380 - 18 September 2020

    Abstract In the area of pattern recognition and machine learning, features play a key role in prediction. The famous applications of features are medical imaging, image classification, and name a few more. With the exponential growth of information investments in medical data repositories and health service provision, medical institutions are collecting large volumes of data. These data repositories contain details information essential to support medical diagnostic decisions and also improve patient care quality. On the other hand, this growth also made it difficult to comprehend and utilize data for various purposes. The results of imaging data… More >

  • Open Access

    ARTICLE

    High-Fidelity Tetrahedral Mesh Generation from Medical Imaging Data for Fluid-Structure Interaction Analysis of Cerebral Aneurysms

    Yongjie Zhang1, Wenyan Wang1, Xinghua Liang1, Yuri Bazilevs2, Ming-Chen Hsu2, Trond Kvamsdal3, Reidar Brekken4, Jørgen Isaksen5

    CMES-Computer Modeling in Engineering & Sciences, Vol.42, No.2, pp. 131-150, 2009, DOI:10.3970/cmes.2009.042.131

    Abstract This paper describes a comprehensive and high-fidelity finite element meshing approach for patient-specific arterial geometries from medical imaging data, with emphasis on cerebral aneurysm configurations. The meshes contain both the blood volume and solid arterial wall, and are compatible at the fluid-solid interface. There are four main stages for this meshing method: 1) Image segmentation and geometric model construction; 2) Tetrahedral mesh generation for the fluid volume using the octree-based method; 3) Mesh quality improvement stage, in which edge-contraction, pillowing, optimization, geometric flow smoothing, and mesh cutting are applied to the fluid mesh; and 4) More >

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