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  • Open Access

    PROCEEDINGS

    Series-Parallel Machine Learning-Generated Five-Site Water Models for Ice Ih and Liquid: TIP5P-BG and TIP5P-BGT

    Jian Wang1,*, Haitao Hei1, Yonggang Zheng1, Hongwu Zhang1, Hongfei Ye1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.3, pp. 1-2, 2024, DOI:10.32604/icces.2024.010916

    Abstract Icing is a ubiquitous phenomenon in nature and widely observed in the micro/nanoconfinement, e.g., two-dimensional ice growth on Au surface, nanoconfinement-induced phase change, nanodroplet freezing on surface, etc. These complicated and abstruse processes and behaviours demand deep understanding from the microscale level by the aid of molecular dynamics (MD) simulation [1]. However, it is still a great challenge to accurately describe the ice and liquid water simultaneously with the present water models [1,2]. In response to this, we propose a series-parallel machine learning (ML) approach consisting of classification back-propagation neural network (BPNN), parallel regression BPNNs… More >

  • Open Access

    REVIEW

    Spliceosome-mediated RNA trans-splicing: a strategy for Huntington’s disease gene therapy

    QINGYANG ZHANG, SHUXIAN HUANG, DAN WENG*

    BIOCELL, Vol.48, No.10, pp. 1443-1453, 2024, DOI:10.32604/biocell.2024.053794 - 02 October 2024

    Abstract Huntington’s disease (HD) is a debilitating neurodegenerative disorder caused by an abnormal expansion of CAG repeats (Cytosine, Adenine, Guanine) in the huntingtin gene (HTT). This mutation leads to the production of a mutant huntingtin protein, resulting in neuronal dysfunction and cell death. Current treatments primarily focus on symptomatic relief and do not address the underlying genetic cause. This review explores spliceosome-mediated RNA trans-splicing (SMaRT) therapy as an innovative and potential approach for HD treatment. SMaRT leverages the cell’s natural splicing machinery to correct mutant mRNA, thereby reducing toxic protein levels while restoring functional protein production. We More >

  • Open Access

    ARTICLE

    EV Charging Station Load Prediction in Coupled Urban Transportation and Distribution Networks

    Benxin Li*, Xuanming Chang

    Energy Engineering, Vol.121, No.10, pp. 3001-3018, 2024, DOI:10.32604/ee.2024.051332 - 11 September 2024

    Abstract The increasingly large number of electric vehicles (EVs) has resulted in a growing concern for EV charging station load prediction for the purpose of comprehensively evaluating the influence of the charging load on distribution networks. To address this issue, an EV charging station load prediction method is proposed in coupled urban transportation and distribution networks. Firstly, a finer dynamic urban transportation network model is formulated considering both nodal and path resistance. Then, a finer EV power consumption model is proposed by considering the influence of traffic congestion and ambient temperature. Thirdly, the Monte Carlo method… More > Graphic Abstract

    EV Charging Station Load Prediction in Coupled Urban Transportation and Distribution Networks

  • Open Access

    ARTICLE

    Influence of Surface Ice Roughness on the Aerodynamic Performance of Wind Turbines

    Xin Guan1,2,*, Mingyang Li1, Shiwei Wu1, Yuqi Xie1, Yongpeng Sun1

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.9, pp. 2029-2043, 2024, DOI:10.32604/fdmp.2024.049499 - 23 August 2024

    Abstract The focus of this research was on the equivalent particle roughness height correction required to account for the presence of ice when determining the performances of wind turbines. In particular, two icing processes (frost ice and clear ice) were examined by combining the FENSAP-ICE and FLUENT analysis tools. The ice type on the blade surfaces was predicted by using a multi-time step method. Accordingly, the influence of variations in icing shape and ice surface roughness on the aerodynamic performance of blades during frost ice formation or clear ice formation was investigated. The results indicate that More >

  • Open Access

    ARTICLE

    CoopAI-Route: DRL Empowered Multi-Agent Cooperative System for Efficient QoS-Aware Routing for Network Slicing in Multi-Domain SDN

    Meignanamoorthi Dhandapani*, V. Vetriselvi, R. Aishwarya

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2449-2486, 2024, DOI:10.32604/cmes.2024.050986 - 08 July 2024

    Abstract The emergence of beyond 5G networks has the potential for seamless and intelligent connectivity on a global scale. Network slicing is crucial in delivering services for different, demanding vertical applications in this context. Next-generation applications have time-sensitive requirements and depend on the most efficient routing path to ensure packets reach their intended destinations. However, the existing IP (Internet Protocol) over a multi-domain network faces challenges in enforcing network slicing due to minimal collaboration and information sharing among network operators. Conventional inter-domain routing methods, like Border Gateway Protocol (BGP), cannot make routing decisions based on performance,… More >

  • Open Access

    ARTICLE

    Research on the Icing Diagnosis of Wind Turbine Blades Based on FS–XGBoost–EWMA

    Jicai Guo1,2, Xiaowen Song1,2,*, Chang Liu1,2, Yanfeng Zhang1,2, Shijie Guo1,2, Jianxin Wu1,2, Chang Cai3, Qing’an Li3,*

    Energy Engineering, Vol.121, No.7, pp. 1739-1758, 2024, DOI:10.32604/ee.2024.048854 - 11 June 2024

    Abstract In winter, wind turbines are susceptible to blade icing, which results in a series of energy losses and safe operation problems. Therefore, blade icing detection has become a top priority. Conventional methods primarily rely on sensor monitoring, which is expensive and has limited applications. Data-driven blade icing detection methods have become feasible with the development of artificial intelligence. However, the data-driven method is plagued by limited training samples and icing samples; therefore, this paper proposes an icing warning strategy based on the combination of feature selection (FS), eXtreme Gradient Boosting (XGBoost) algorithm, and exponentially weighted… More >

  • Open Access

    ARTICLE

    Study of Flow and Heat Transfer in an Ejector-Driven Swirl Anti-Icing Chamber

    Yi Tu1,*, Yuan Wu2, Yu Zeng3

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 989-1014, 2024, DOI:10.32604/fdmp.2024.045624 - 07 June 2024

    Abstract The formation of ice on the leading edge of aircraft engines is a serious issue, as it can have catastrophic consequences. The Swirl Anti-Icing (SAI) system, driven by ejection, circulates hot fluid within a 360° annular chamber to heat the engine inlet lip surface and prevent icing. This study employs a validated Computational Fluid Dynamics (CFD) approach to study the impact of key geometric parameters of this system on flow and heat transfer characteristics within the anti-icing chamber. Additionally, the entropy generation rate and exergy efficiency are analyzed to assess the energy utilization in the… More >

  • Open Access

    ARTICLE

    A Distributionally Robust Optimization Scheduling Model for Regional Integrated Energy Systems Considering Hot Dry Rock Co-Generation

    Hao Qi1, Mohamed Sharaf2, Andres Annuk3, Adrian Ilinca4, Mohamed A. Mohamed5,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1387-1404, 2024, DOI:10.32604/cmes.2024.048672 - 20 May 2024

    Abstract Hot dry rock (HDR) is rich in reserve, widely distributed, green, low-carbon, and has broad development potential and prospects. In this paper, a distributionally robust optimization (DRO) scheduling model for a regionally integrated energy system (RIES) considering HDR co-generation is proposed. First, the HDR-enhanced geothermal system (HDR-EGS) is introduced into the RIES. HDR-EGS realizes the thermoelectric decoupling of combined heat and power (CHP) through coordinated operation with the regional power grid and the regional heat grid, which enhances the system wind power (WP) feed-in space. Secondly, peak-hour loads are shifted using price demand response guidance More >

  • Open Access

    ARTICLE

    Research on Operation Optimization of Energy Storage Power Station and Integrated Energy Microgrid Alliance Based on Stackelberg Game

    Yu Zhang*, Lianmin Li, Zhongxiang Liu, Yuhu Wu

    Energy Engineering, Vol.121, No.5, pp. 1209-1221, 2024, DOI:10.32604/ee.2024.046141 - 30 April 2024

    Abstract With the development of renewable energy technologies such as photovoltaics and wind power, it has become a research hotspot to improve the consumption rate of new energy and reduce energy costs through the deployment of energy storage. To solve the problem of the interests of different subjects in the operation of the energy storage power stations (ESS) and the integrated energy multi-microgrid alliance (IEMA), this paper proposes the optimization operation method of the energy storage power station and the IEMA based on the Stackelberg game. In the upper layer, ESS optimizes charging and discharging decisions More > Graphic Abstract

    Research on Operation Optimization of Energy Storage Power Station and Integrated Energy Microgrid Alliance Based on Stackelberg Game

  • Open Access

    ARTICLE

    A Fair and Trusted Trading Scheme for Medical Data Based on Smart Contracts

    Xiaohui Yang, Kun Zhang*

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 1843-1859, 2024, DOI:10.32604/cmc.2023.047660 - 27 February 2024

    Abstract Data is regarded as a valuable asset, and sharing data is a prerequisite for fully exploiting the value of data. However, the current medical data sharing scheme lacks a fair incentive mechanism, and the authenticity of data cannot be guaranteed, resulting in low enthusiasm of participants. A fair and trusted medical data trading scheme based on smart contracts is proposed, which aims to encourage participants to be honest and improve their enthusiasm for participation. The scheme uses zero-knowledge range proof for trusted verification, verifies the authenticity of the patient’s data and the specific attributes of… More >

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