Tong Cao1,2,3,*, Xiangyu Hu1,3, Yusu Zhang1,2, Lihong Wang1,2, Dandan Lu1,3, Jinhua Wu1,2, Chenyu Qiu1,2, Siyun Lei1,2, Qian Luo1,2, Jie Wang1,2, Jing Zhou1,3, Yang Cheng1,2, Jinpeng Xie1,2, Ting Kou1,2, Jue Wang1,3, Lei Xu1,2, Xinlei Wei1, Gu Cheng1,3, Xin Fu1, Shukuan Ling1, Yihuai Pan3, Wujun Geng1,4
The International Conference on Computational & Experimental Engineering and Sciences, Vol.29, No.4, pp. 1-2, 2024, DOI:10.32604/icces.2024.012775
Abstract Government authorities, academies, research institutes and industries are presently hindered by a lack of functional, healthy and standardized human platforms of cells, tissues, and organs, predominantly using costly live animal models and cells of low human relevance. Existing models of live animals or immortalized cell lines of either animal or human origin, often poorly reflect human physiology. Primary human cell cultures are difficult to procure in sufficient quantity and can be prone to much inter-batch variability, depending on the cell source. By contrast, self-renewable, genetically healthy and single-sourced human pluripotent stem cells (PSCs) exhibit enhanced… More >
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