Shuangsheng Zhang, Bin Sun, Siyu Li, Xiangyu Lin, Muhua Chen^*, Xu Xu^*

Journal of Renewable Materials, Vol.11, No.2, pp. 853-865, 2023, DOI:10.32604/jrm.2022.022901

Abstract Hydrogels have been widely applied in agricultural drought-resistance, pollution regulation, drug delivery and so on. Acrylamide (AM) is usually used as raw material to synthesize acrylamide hydrogels. However, inherently low mechanical strength greatly limits their applications in some special areas. Therefore, it is necessary to choose suitable functional monomers to optimize acrylamide hydrogels and improve their mechanical performances. In this paper, a novel acrylamide monomer modified by rosin was synthesized, and then polyacrylamide/rosin-based acrylamide (RAM) composite hydrogels were prepared via free radical polymerization using potassium persulfate as initiator, N, N′-methylene-bisacrylamide (MBA) as a crosslinker. The influence of RAM monomer was… More > Graphic Abstract

Dongqing Wang^1,*, Heying Chen¹, Yi Hu^2,*

Oncologie, Vol.24, No.3, pp. 441-449, 2022, DOI:10.32604/oncologie.2022.024898

Abstract Immunotherapy is currently recognized as one of the most promising anticancer strategies. In the tumor microenvironment, tumor-associated macrophages are mainly M2-type macrophages with tumor-promoting effects. Therefore, the reprogramming of tumor-associated macrophages from M2 to M1 type is a potential strategy for cancer therapy. We have previously shown the anticancer effects of implantable allogeneic M1 macrophages in mice. Here, we further engineered autologous mouse bone marrow cells into M1 macrophages and then embedded them into a sodium alginate gel to prepare an implantable immunotherapeutic agent (M1@Gel). We demonstrate that M1@Gel repolarizes M2 macrophages to M1 type and activates the immune responses… More >

Yanxia Zhang¹, Tiina Nypelö^1,*, Carlos Salas¹, Julio Arboleda¹, Ingrid C. Hoeger^1,*, Orlando J. Rojas^1,2,*

Journal of Renewable Materials, Vol.1, No.3, pp. 195-211, 2013, DOI:10.7569/JRM.2013.634115

Abstract Cellulose nanofi brils (CNF), also known as nanofi brillar cellulose (NFC), are an advanced biomaterial made mainly from renewable forest and agricultural resources that have demonstrated exceptional performance in composites. In addition, they have been utilized in barrier coatings, food, transparent fl exible fi lms and other applications. Research on CNF has advanced rapidly over the last decade and several of the fundamental questions about production and characterization of CNF have been addressed. An interesting shift in focus in the recent reported literature indicates increased efforts aimed at taking advantage of the unique properties of CNF. This includes its nanoscale… More >

Yiming Zhao^1,2, Hongsheng Zhao³, Zhili Wei⁴, Jie Yuan¹, Jie Jian¹, Fankai Kong¹, Haojiang Xie¹, Xingliang Xiong^1,2,*

Journal of Renewable Materials, Vol.10, No.11, pp. 2729-2746, 2022, DOI:10.32604/jrm.2022.019721

Abstract The flexible wearable sensors with excellent stretchability, high sensitivity and good biocompatibility are signifi- cantly required for continuously physical condition tracking in health management and rehabilitation monitoring. Herein, we present a high-performance wearable sensor. The sensor is prepared with nanocomposite hydrogel by using silk fibroin (SF), polyacrylamide (PAM), polydopamine (PDA) and graphene oxide (GO). It can be used to monitor body motions (including large-scale and small-scale motions) as well as human electrophysiological (ECG) signals with high sensitivity, wide sensing range, and fast response time. Therefore, the proposed sensor is promising in the fields of rehabilitation, motion monitoring and disease diagnosis. More >

Diego David Pinzón-Moreno^*, Eder Clidio Vicuña-Galindo, José Vulfrano González-Fernández, José Luis Soto-Gonzales, María Verónica Carranza-Oropeza^*

Journal of Renewable Materials, Vol.10, No.8, pp. 2179-2201, 2022, DOI:10.32604/jrm.2022.019793

Abstract Several hydrogels were synthesized by free-radical polymerization in an aqueous medium based on potato starch (PS), poly(vinyl alcohol) (PVA), and N,N′-Methylenebisacrylamide (MBAm), being possible to study these hydrogels as a function of the proportion of components incorporated. In this way, the products generated from the synthesis were characterized by swelling and deswelling kinetics, the first swelling being verified with Schott and statistical models, allowing to contrast the proximity between the experimental and theoretical behavior. Additionally, water retention in soil (R%), spectroscopy (FTIR), morphological (SEM), and thermal (TGA and DSC) analysis allowing to know the intrinsic characteristics of the material, increasing… More >

MASSIMO CONESE^1,*, AURELIO PORTINCASA²

BIOCELL, Vol.46, No.8, pp. 1815-1826, 2022, DOI:10.32604/biocell.2022.019448

Abstract The treatment of nonhealing and chronic cutaneous wounds still needs a clinical advancement to be effective. Both mesenchymal stem cells (MSCs), obtained from different sources, and their secretome derived thereof (especially exosomes) can activate signaling pathways related to promotion of cell migration, vascularization, collagen deposition, and inflammatory response demonstrating prohealing, angiogenetic and anti-scarring capacities. On the other hand, biodegradable biomimetic scaffolds can facilitate endogenous cell attachment and proliferation as well as extracellular matrix production. In this Review, we revise the complex composites made by biomimetic scaffolds, mainly hydrogels, and MSC-derived exosomes constructed for cutaneous wound healing. Studies demonstrate that there… More >

Hebat-Allah S. Tohamy, Mohamed El-Sakhawy, Samir Kamel^*

Journal of Renewable Materials, Vol.10, No.7, pp. 1889-1909, 2022, DOI: 10.32604/jrm.2022.019211

Abstract A novel magnetic hydrogel loaded with graphene oxide (GO) was developed in this study. Firstly, GO was prepared from bagasse through a single step via oxidation in the presence of ferrocene under muffled atmospheric conditions, followed by the loading of different amounts of magnetite onto GO via co-precipitation reaction of iron onto GO sheets. Finally, the 2-acrylamido-2-methyl-1-propane sulfonic acid was grafted onto carboxymethyl cellulose in the presence of magnetite GO and N, N′-methylenebisacrylamide as crosslinker yielded hydrogel. The structure, morphological, and thermal behavior of the prepared hydrogels were investigated. In addition, the adsorption performance of Ni(II) ions from aqueous media… More > Graphic Abstract

YUNLONG ZHANG^1,#, JINGWEI ZHANG^2,#, YU ZHU¹, BIN CAI^1,*

BIOCELL, Vol.46, No.5, pp. 1329-1338, 2022, DOI:10.32604/biocell.2022.015592

Abstract Diabetic patients often exhibit delayed or incomplete progress in the healing of acute wounds, owing to poor blood perfusion. Platelet-rich plasma (PRP) has attracted much attention as a means to improve wound healing, because it contains high growth factor concentrations. However, the burst-like release of PRP growth factors results in a short half-life of these therapeutic proteins, thus greatly limiting the therapeutic effect. In this study, we prepared PRP from human umbilical cord blood and developed an in situ photocrosslinkable PRP hydrogel glue (HNPRP) by adding a photoresponsive hyaluronic acid (HA-NB) into PRP. The HNPRP hydrogel allowed for controlled release… More >

Lingqin Zhang, Qifeng Jiang, Yiming Zhao, Jie Yuan, Xiaoying Zha, Haojiang Xie, Fankai Kong, Xingliang Xiong^*

Journal of Renewable Materials, Vol.10, No.2, pp. 415-430, 2022, DOI:10.32604/jrm.2022.016650

Abstract The hydrogel is a preferred material for flexible wearable sensors. In practical application, it should have high-efficiency mechanical toughness and self-healing performance. Besides, hydrogel requires good affinity and adhesion because of its contact with the skin. In this experiment, we made an ultra-tough hydrogel with excellent cell affinity and adhesion. We used sodium alginate (SA) and polyacrylamide (PAm) mixture as a flexible base fluid. Polydopamine reduce graphene oxide (prGO) was used as conductive nanofiller, and then PAm-prGO-SA semi-interpenetrating network hydrogel was formed through Am radical polymerization. The presence of prGO endows the hydrogels with excellent electrical conductivity. Simultaneously, some non-reduced… More >

BARKAT ALI KHAN¹, FAZAL KARIM¹, MUHAMMAD KHALID KHAN^1,*, FAHEEM HAIDER¹, SADIQULLAH KHAN²

BIOCELL, Vol.45, No.5, pp. 1273-1285, 2021, DOI:10.32604/biocell.2021.015323

Abstract The fourth most predominant overwhelming type of trauma is burn injuries worldwide. Ideal wound healing dressings help in the wound healing process in a lower time with less pain. Commonly used dry wound dressing, like absorbent gauze or absorbent cotton, possess limited therapeutic effects and require repeated use, which further exaggerates patients’ suffering. In contrast, hydrogels films present a promising alternative to improve healing by guaranteeing a moisture balance at the wound site. The aim of the current study was to synthesize Tamarix aphylla (T. aphylla) extract-loaded hydrogel film with Na-CMC and pectin and to study their wound healing properties.… More >