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  • Open Access

    REVIEW

    Modulatory role of plant-derived metabolites on host-microbiota interactions: personalized therapeutics outlook

    POOJA YADAV, NAR SINGH CHAUHAN*

    BIOCELL, Vol.48, No.8, pp. 1127-1143, 2024, DOI:10.32604/biocell.2024.051318 - 02 August 2024

    Abstract A diverse array of microbes in and on the human body constitute the microbiota. These micro-residents continuously interact with the human host through the language of metabolites to dictate the host’s physiology in health and illnesses. Any biotic and abiotic component ensuring a balanced host-microbiota interaction are potential microbiome therapeutic agents to overcome human diseases. Plant metabolites are continually being used to treat various illnesses. These metabolites target the host’s metabolic machinery and host-gut microbiota interactions to overcome human diseases. Despite the paramount therapeutic significance of the factors affecting host-microbiota interactions, a comprehensive overview of More > Graphic Abstract

    Modulatory role of plant-derived metabolites on host-microbiota interactions: personalized therapeutics outlook

  • Open Access

    ARTICLE

    An Intelligent Hazardous Waste Detection and Classification Model Using Ensemble Learning Techniques

    Mesfer Al Duhayyim1,*, Saud S. Alotaibi2, Shaha Al-Otaibi3, Fahd N. Al-Wesabi4, Mahmoud Othman5, Ishfaq Yaseen6, Mohammed Rizwanullah6, Abdelwahed Motwakel6

    CMC-Computers, Materials & Continua, Vol.74, No.2, pp. 3315-3332, 2023, DOI:10.32604/cmc.2023.033250 - 31 October 2022

    Abstract Proper waste management models using recent technologies like computer vision, machine learning (ML), and deep learning (DL) are needed to effectively handle the massive quantity of increasing waste. Therefore, waste classification becomes a crucial topic which helps to categorize waste into hazardous or non-hazardous ones and thereby assist in the decision making of the waste management process. This study concentrates on the design of hazardous waste detection and classification using ensemble learning (HWDC-EL) technique to reduce toxicity and improve human health. The goal of the HWDC-EL technique is to detect the multiple classes of wastes,… More >

  • Open Access

    ARTICLE

    In silico assessment of human health risks caused by cyanotoxins from cyanobacteria

    JIA-FONG HONG1, BAGHDAD OUDDANE2, JIANG-SHIOU HWANG3,4,5, HANS-UWE DAHMS1,6,7,*

    BIOCELL, Vol.45, No.1, pp. 65-77, 2021, DOI:10.32604/biocell.2021.014154 - 26 January 2021

    Abstract Harmful algal blooms (HABs) that are formed by cyanobacteria have become a serious issue worldwide in recent years. Cyanobacteria can release a type of secondary metabolites called cyanotoxins into aquatic systems which may indirectly or directly provide health risks to the environment and humans. Cyanotoxins provide some of the most powerful natural poisons including potent neurotoxins, hepatotoxins, cytotoxins, and endotoxins that may result in environmental health risks, and long-term morbidity and mortality to animals and humans. In this research, we used the chemcomputational tool Molinspiration for molecular property predictions, Pred-hERG 4.2 web software for cardiac… More >

  • Open Access

    REVIEW

    Plant Derived Antiviral Products for Potential Treatment of COVID-19: A Review

    Rashid Iqbal Khan1,*, Mazhar Abbas1, Khurram Goraya2, Muhammad Zafar-ul-Hye3, Subhan Danish3

    Phyton-International Journal of Experimental Botany, Vol.89, No.3, pp. 438-452, 2020, DOI:10.32604/phyton.2020.010972 - 22 June 2020

    Abstract COVID-19 caused by SARS-CoV-2 is declared global pandemic. The virus owing high resemblance with SARS-CoV and MERS-CoV has been placed in family of beta-coronavirus. However, transmission and infectivity rate of COVID-19 is quite higher as compared to other members of family. Effective management strategy with potential drug availability will break the virus transmission chain subsequently reduce the pressure on the healthcare system. Extensive research trials are underway to develop novel efficient therapeutics against SARS-CoV-2. In this review, we have discussed the origin and family of coronavirus, structure, genome and pathogenesis of virus SARS-CoV-2 inside human More >

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