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  • Open Access

    ARTICLE

    Nuclei Segmentation in Histopathology Images Using Structure-Preserving Color Normalization Based Ensemble Deep Learning Frameworks

    Manas Ranjan Prusty1, Rishi Dinesh2, Hariket Sukesh Kumar Sheth2, Alapati Lakshmi Viswanath2, Sandeep Kumar Satapathy2,3,*

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3077-3094, 2023, DOI:10.32604/cmc.2023.042718 - 26 December 2023

    Abstract This paper presents a novel computerized technique for the segmentation of nuclei in hematoxylin and eosin (H&E) stained histopathology images. The purpose of this study is to overcome the challenges faced in automated nuclei segmentation due to the diversity of nuclei structures that arise from differences in tissue types and staining protocols, as well as the segmentation of variable-sized and overlapping nuclei. To this extent, the approach proposed in this study uses an ensemble of the UNet architecture with various Convolutional Neural Networks (CNN) architectures as encoder backbones, along with stain normalization and test time… More >

  • Open Access

    ARTICLE

    Recognizing Breast Cancer Using Edge-Weighted Texture Features of Histopathology Images

    Arslan Akram1,2, Javed Rashid2,3,4, Fahima Hajjej5, Sobia Yaqoob1,6, Muhammad Hamid7, Asma Irshad8, Nadeem Sarwar9,*

    CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 1081-1101, 2023, DOI:10.32604/cmc.2023.041558 - 31 October 2023

    Abstract Around one in eight women will be diagnosed with breast cancer at some time. Improved patient outcomes necessitate both early detection and an accurate diagnosis. Histological images are routinely utilized in the process of diagnosing breast cancer. Methods proposed in recent research only focus on classifying breast cancer on specific magnification levels. No study has focused on using a combined dataset with multiple magnification levels to classify breast cancer. A strategy for detecting breast cancer is provided in the context of this investigation. Histopathology image texture data is used with the wavelet transform in this… More >

  • Open Access

    ARTICLE

    A Framework of Deep Learning and Selection-Based Breast Cancer Detection from Histopathology Images

    Muhammad Junaid Umer1, Muhammad Sharif1, Majed Alhaisoni2, Usman Tariq3, Ye Jin Kim4, Byoungchol Chang5,*

    Computer Systems Science and Engineering, Vol.45, No.2, pp. 1001-1016, 2023, DOI:10.32604/csse.2023.030463 - 03 November 2022

    Abstract Breast cancer (BC) is a most spreading and deadly cancerous malady which is mostly diagnosed in middle-aged women worldwide and effecting beyond a half-million people every year. The BC positive newly diagnosed cases in 2018 reached 2.1 million around the world with a death rate of 11.6% of total cases. Early diagnosis and detection of breast cancer disease with proper treatment may reduce the number of deaths. The gold standard for BC detection is biopsy analysis which needs an expert for correct diagnosis. Manual diagnosis of BC is a complex and challenging task. This work… More >

  • Open Access

    ARTICLE

    A Stacked Ensemble-Based Classifier for Breast Invasive Ductal Carcinoma Detection on Histopathology Images

    Ali G. Alkhathami*

    Intelligent Automation & Soft Computing, Vol.34, No.1, pp. 235-247, 2022, DOI:10.32604/iasc.2022.024952 - 15 April 2022

    Abstract Breast cancer is one of the main causes of death in women. When body tissues start behaves abnormally and the ratio of tissues growth becomes asymmetrical then this stage is called cancer. Invasive ductal carcinoma (IDC) is the early stage of breast cancer. The early detection and diagnosis of invasive ductal carcinoma is a significant step for the cure of IDC breast cancer. This paper presents a convolutional neural network (CNN) approach to detect and visualize the IDC tissues in breast on histological images dataset. The dataset consists of 90 thousand histopathological images containing two… More >

  • Open Access

    ARTICLE

    ResNet50-Based Effective Model for Breast Cancer Classification Using Histopathology Images

    Nishant Behar*, Manish Shrivastava

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.2, pp. 823-839, 2022, DOI:10.32604/cmes.2022.017030 - 13 December 2021

    Abstract Breast cancer is considered an immense threat and one of the leading causes of mortality in females. It is curable only when detected at an early stage. A standard cancer diagnosis approach involves detection of cancer-related anomalies in tumour histopathology images. Detection depends on the accurate identification of the landmarks in the visual artefacts present in the slide images. Researchers are continuously striving to develop automatic machine-learning algorithms for processing medical images to assist in tumour detection. Nowadays, computer-based automated systems play an important role in cancer image analysis and help healthcare experts make rapid… More >

  • Open Access

    ARTICLE

    Automated Grading of Breast Cancer Histopathology Images Using Multilayered Autoencoder

    Shakra Mehak1, M. Usman Ashraf2, Rabia Zafar3, Ahmed M. Alghamdi4, Ahmed S. Alfakeeh5, Fawaz Alassery6, Habib Hamam7, Muhammad Shafiq8,*

    CMC-Computers, Materials & Continua, Vol.71, No.2, pp. 3407-3423, 2022, DOI:10.32604/cmc.2022.022705 - 07 December 2021

    Abstract Breast cancer (BC) is the most widely recognized cancer in women worldwide. By 2018, 627,000 women had died of breast cancer (World Health Organization Report 2018). To diagnose BC, the evaluation of tumours is achieved by analysis of histological specimens. At present, the Nottingham Bloom Richardson framework is the least expensive approach used to grade BC aggressiveness. Pathologists contemplate three elements, 1. mitotic count, 2. gland formation, and 3. nuclear atypia, which is a laborious process that witness's variations in expert's opinions. Recently, some algorithms have been proposed for the detection of mitotic cells, but… More >

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