Neslihan Duzkale1,*, Emine Demıral2
Oncologie, Vol.22, No.4, pp. 225-234, 2020, DOI:10.32604/oncologie.2020.014120
Abstract Multiple primary malignant neoplasms (MPMN) are rare tumors that
have attracted attention with increasing incidence rates in recent years and where
cancer susceptibility genes may play a role in their etiology. In this study, it was
aimed to determine the genotype-phenotype correlation in patients with MPMN.
From January 2018 to January 2020, thirty patients were analyzed for 59 cancer
susceptibility genes and diagnosed with MPMN, using a large multigene panel
with Next Generation Sequencing technique (NGS) in Turkey. The mean age of
first and second cancer diagnosis of cases were calculated as 42.5 and 49.9… More >
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