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  • Open Access

    ARTICLE

    Crude Flavonoid Extract of Medicinal Herb Zingibar officinale Inhibits Proliferation and Induces Apoptosis in Hepatocellular Carcinoma Cells

    Ayman I. Elkady*†, Osama A. Abu-Zinadah*, Rania Abd El Hamid Hussein‡§

    Oncology Research, Vol.25, No.6, pp. 897-912, 2017, DOI:10.3727/096504016X14816352324532

    Abstract There is an urgent need to improve the clinical management of hepatocellular carcinoma (HCC), one of the most common causes of global cancer-related deaths. Zingibar officinale is a medicinal herb used throughout history for both culinary and medicinal purposes. It has antioxidant, anticarcinogenic, and free radical scavenging properties. Previously, we proved that the crude flavonoid extract of Z. officinale (CFEZO) inhibited growth and induced apoptosis in several cancer cell lines. However, the effect of the CFEZO on an HCC cell line has not yet been evaluated. In this study, we explored the anticancer activity of CFEZO against… More >

  • Open Access

    ARTICLE

    Grazing Pressure and Plant Functional Types in Puna Highlands, Northwestern Argentina

    Quiroga Mendiola Mariana1,2,*, Tálamo Andrés3,4

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 1067-1080, 2024, DOI:10.32604/phyton.2024.050556

    Abstract The Puna grasslands support grazing systems that produce meat and wool in multi-species herds, especially from llama (Lama glama) and sheep. However, it is yet unknown whether grazing pressure can modify grassland structure and Plant Functional Types diversity and cover in Puna grasslands. We analyzed the relationship between grazing pressure and Plant Functional Types by comparing transects located near stockyards (high grazing pressure) and far from them (low pressure) and by evaluating the relationship between the Plant Functional Types cover to a Grazing Pressure Index (GPI). This index incorporates the heterogeneity of traditional pastoral management. At… More >

  • Open Access

    ARTICLE

    A Multilayer Network Constructed for Herb and Prescription Efficacy Analysis

    Xindi Huang1, Liwei Liang1, Sakirin Tam2, Hao Liang3, Xiong Cai4, Changsong Ding1,5,*

    Computer Systems Science and Engineering, Vol.48, No.3, pp. 691-704, 2024, DOI:10.32604/csse.2022.029970

    Abstract Chinese Medicine (CM) has been widely used as an important avenue for disease prevention and treatment in China especially in the form of CM prescriptions combining sets of herbs to address patients’ symptoms and syndromes. However, the selection and compatibility of herbs are complex and abstract due to intrinsic relationships between herbal properties and their overall functions. Network analysis is applied to demonstrate the complex relationships between individual herbal efficacy and the overall function of CM prescriptions. To illustrate their connections and correlations, prescription function (PF), prescription herb (PH), and herbal efficacy (HE) intra-networks are… More >

  • Open Access

    REVIEW

    Plant Chemical Defenses against Insect Herbivores—Using the Wild Tobacco as a Model

    Guangwei Sun1,2,#, Xuanhao Zhang3,#, Yi Liu3, Liguang Chai2, Daisong Liu2, Zhenguo Chen1,*, Shiyou Lü3,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 641-659, 2024, DOI:10.32604/phyton.2024.049285

    Abstract The Nicotiana genus, commonly known as tobacco, holds significant importance as a crucial economic crop. Confronted with an abundance of herbivorous insects that pose a substantial threat to yield, tobacco has developed a diverse and sophisticated array of mechanisms, establishing itself as a model of plant ecological defense. This review provides a concise overview of the current understanding of tobacco’s defense strategies against herbivores. Direct defenses, exemplified by its well-known tactic of secreting the alkaloid nicotine, serve as a potent toxin against a broad spectrum of herbivorous pests. Moreover, in response to herbivore attacks, tobacco enhances… More >

  • Open Access

    ARTICLE

    Exploration of the oxidative-inflammatory potential targets of Coicis Semen in osteoarthritis: Data mining and systematic pharmacology

    QIAO ZHOU2,3,4, JIAN LIU1,2,*, LING XIN1, YANYAN FANG1,2, LEI WAN1,2, DAN HUANG1,2, JIANTING WEN1,2

    BIOCELL, Vol.47, No.7, pp. 1623-1643, 2023, DOI:10.32604/biocell.2023.028331

    Abstract Objective: On the basis of data mining, systematic pharmacology, molecular docking, and experiment validation, the oxidative-inflammatory molecular targets of Coicis Semen in the therapy of osteoarthritis (OA) were explored. Methods: The association rule analysis was effectively applied to highlight the correlation between Coicis Semen and oxidative inflammation indices. The random walk model was subsequently used to evaluate the clinical efficacy of Coicis Semen. Network pharmacology was used to predict network targets. The binding affinity of the active ingredient in Coicis Semen to the key target of OA was also successfully predicted. Results: Coicis Semen showed a significant reduction in oxidative-inflammatory indicators… More >

  • Open Access

    ARTICLE

    Pollination Biology of the Endangered Herbal Medicines Dendrobium chrysotoxum (Orchidaceae)

    Kai Luo1, Yanbing Bai1, Yan Jiang1, Guiling Li1, Min Jia1, Yongguo He1, Zhijun Yao1, Ziwei Xiao1, Xiaoqiong Liu1, Wenjie Liu2, Shanshan Yin1,*, Zesheng Li1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 1975-1986, 2023, DOI:10.32604/phyton.2023.028232

    Abstract Pollination biology studies of the endangered herbal medicines Dendrobium chrysotoxum were conducted in natural pollination conditions using flower observation, pollinator observation and artificial pollination experiments. Populations of D. chrysotoxum with fragrance and nectar were pollinated by Ctenoplectra davidi Valhalla (Hymenoptera: Apidae) species. The floral structure of D. chrysotoxum adapted precisely to its pollinators. Flowers had a low capsule setting (0.17%) under natural conditions. However, compared to open pollination, artificial pollination experiments showed a significant increase in capsule setting, and D. chrysotoxum was cross-compatible and self-compatible, but there was pollinator limitation also. This study will provide important information for the preservation More >

  • Open Access

    REVIEW

    SOLAR DRYING OF HERBAL WEALTH IN EASTERN HIMALAYA: A REVIEW

    Priyanka Chauhana , Himani Pathaniaa, Shriyaa, Neetikaa, Nidhia, Sakshia, Sheetal Choudharya, Rajesh Kumarb,*, Mamta Sharmaa,c,*, Sameer Rahatekard, Anil Kumare,*

    Frontiers in Heat and Mass Transfer, Vol.18, pp. 1-20, 2022, DOI:10.5098/hmt.18.34

    Abstract Solar dryers have proven to be one of the best environmentally friendly approaches for drying purpose of medicinal plants and agricultural crops. Use of solar radiations in drying purpose of plant parts has proven economically as well as environmentally responsible and sensible application. Plants are the treasure of nature with hidden medicinal properties to treat diseases. Plant material should be processed properly for extraction of medicinal molecules in terms drying to decrease the manufacturing loss and to increase the standard of product. Cognizances of ethnobotanical knowledge on plant wealth are extremely beneficial in utilization and… More >

  • Open Access

    ARTICLE

    Evaluation of Pre-Emergence and Post-Emergence Herbicides for Weed Management in Miscanthus sacchariflorus and Miscanthus sinensis

    Bimal Kumar Ghimire1, Chang Yeon Yu2, Seung Hyun Kim1, Ill Min Chung1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.5, pp. 1439-1467, 2023, DOI:10.32604/phyton.2023.023076

    Abstract Miscanthus, is a promising bioenergy crop, considered superior to other bioenergy crops because of its higher water and nutrient use efficiency, cold tolerance, and higher production of biomass. Broadleaf weeds and grass weeds, cause major problems in the Miscanthus field. A field experiment was conducted in 2018 and 2019, to assess the effects of pre-emergence (alachlor and napropamide) and post-emergence herbicides (nicosulfuron, dicamba, bentazon, and glufosinate ammonium) on broadleaf and grass weeds in M. sinensis and M. sacchariflorus fields. The weed control efficiency and phytotoxicity of pre- and post-emergence herbicides were evaluated at 30 days after treatment (DAT) and… More >

  • Open Access

    REVIEW

    Indian medicinal plants are effective in the treatment and management of COVID-19

    SUBHASH CHANDRA1,2, SANTWANA PALAI3, EDINARDO FAGNER FERREIRA-MATIAS4, IVO CAVALCANTE PITA-NETO4, CíCERO LUCAS GOMES-RAMALHO4, EDLANE MARTINS DE ANDRADE4, RAY SILVA DE ALMEIDA5, MARCELLO IRITI6,7,*, HENRIQUE DOUGLAS MELO-COUTINHO5,*

    BIOCELL, Vol.47, No.4, pp. 677-695, 2023, DOI:10.32604/biocell.2023.026081

    Abstract Indian medicinal plants are referred to as the “nectar of life” owing to their phytochemicals and bioactive complexes that are beneficial in treating diseases. Coronavirus disease 2019 (COVID-19) is a global health issue without any proper medication. The indigenous plants of India can be exploited to control the precise signs of SARS-CoV-2. The Ministry of AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) has advised routine usage of medicinal plants for COVID-19. Medicinal plants like Zingiber officinalis, Azadirachta indica, Ocimum sanctum, Nigella sativa, Withania somnifera, Curcuma longa, Piper nigrum, Allium sativum, Tinospora cordifolia, etc. have More >

  • Open Access

    ARTICLE

    Selection of Stable Reference Genes for Quantitative Real-Time PCR on Herbaceous Peony (Paeonia lactiflora Pall.) in Response to Drought Stress

    Zhipeng Sheng, Yuting Luan, Cong Xu, Jun Tao*, Daqiu Zhao*

    Phyton-International Journal of Experimental Botany, Vol.92, No.3, pp. 801-814, 2023, DOI:10.32604/phyton.2023.024953

    Abstract Herbaceous peony (Paeonia lactiflora Pall.), as a high-end cut flower in the international market, has high ornamental and medicinal values. But in Northern China, drought is a major environmental factor influencing the growth and development of P. lactiflora. Quantitative real-time polymerase chain reaction (qRT-PCR) can evaluate gene expression levels under different stress conditions, and stable internal reference is the key for qRT-PCR. At present, there is no systematic screening of internal reference for correcting gene expressions of P. lactiflora in response to drought stress. In this study, 10 candidate genes [ubiquitin (UBQ2), UBQ1, elongation factor 1-α (EF-1α), Histidine (His), eukaryotic… More >

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