Liesbeth van Dessel1, Béatrice Santens2, Els Troost2, Pieter De Meester2,3, Leen Roggen2, Filip Rega3,4, Bart Meyns3,4, Bjorn Cools5, Marc Gewillig5, Philip Moons6,7,8, Lukas Meier9, Werner Budts2,3, Alexander Van De Bruaene2,3,*
Congenital Heart Disease, Vol.15, No.2, pp. 69-78, 2020, DOI:10.32604/CHD.2020.011512
- 23 June 2020
Abstract Background: Left-to-right shunt in sinus venosus septal defect (SVSD)
may affect resistive (pulmonary vascular resistance–PVR) and elastic (pulmonary
artery compliance-PAC) pulmonary artery properties. This study aimed at evaluating
(1) impact of age, (2) pulmonary hemodynamics, and (3) outcome in a large cohort
of SVSD patients. Methods: This study included 136 patients with SVSD (median
age at diagnosis 14 (IQR 5–48) years, 47% male) of which 87 underwent
catheterization. Pressures were measured and cardiac output was evaluated using the
Fick principle at diagnosis. PVR, PAC and their product (RC time) were calculated.
Results: Surgical repair was performed in… More >