Wubin Dai¹, Xiuting Ju^1,2, Guomin Shi^1,2, Jialei Guo^3,4, Tao He^3,4,*

Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 1023-1042, 2024, DOI:10.32604/phyton.2024.050066

Abstract Saussurea inversa is one of the Tibetan medicine with developed aerenchyma. In this study, we investigated the function of the ShCTR1 gene related to the formation of aerenchyma. The study of the occurrence and formation of aerenchyma in S. inversa has certain theoretical significance in revealing the special mechanism of alpine plants adapting to the environment. The results of yeast two-hybrid experiments showed that S. inversa ShCTR1 interacted with the ShRBOH1, which is a key producer of reactive oxygen species (ROS), and it was hypothesized that ShCTR1 regulation of aerenchyma formation in S. inversa mainly mediated by ROS. Aerenchyma induction and… More >

Hong Ye^*, Qing Yang^†, Shujie Qi^*, Hairong Li^‡

Oncology Research, Vol.27, No.5, pp. 613-621, 2019, DOI:10.3727/096504018X15410353669149

Abstract Hepatocellular carcinoma (HCC) has high morbidity and mortality rates, and the number of new cases and deaths from liver cancer are increasing. However, the details of the regulation in HCC remain largely unknown. Plant homeodomain finger protein 8 (PHF8) is a JmjC domain-containing protein. Recently, PHF8 was reported to participate in several types of cancer. However, the biological function and clinical significance of PHF8 in HCC remain unknown. In this study, we investigate the role of PHF8 in HCC growth and metastasis. We used bioinformatics analysis and identified the differentially expressed PHF8 in primary HCC… More >