Di Qiu^1,3,4, Rongpei Shi^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 1017-1028, 2024, DOI:10.32604/cmes.2024.048797

Abstract For media with inclusions (e.g., precipitates, voids, reinforcements, and others), the difference in lattice parameter and the elastic modulus between the matrix and inclusions cause stress concentration at the interfaces. These stress fields depend on the inclusions’ size, shape, and distribution and will respond instantly to the evolving microstructure. This study develops a phase-field model concerning modulus heterogeneity. The effect of modulus heterogeneity on the growth process and equilibrium state of the α plate in Ti-6Al-4V during precipitation is evaluated. The α precipitate exhibits strong anisotropy in shape upon cooling due to the interplay of the elastic strain and interfacial… More >

Tianyi Li^1,2, Xin Gu², Qing Zhang^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 339-361, 2024, DOI:10.32604/cmes.2024.047566

Abstract This study proposes a comprehensive, coupled thermomechanical model that replaces local spatial derivatives in classical differential thermomechanical equations with nonlocal integral forms derived from the peridynamic differential operator (PDDO), eliminating the need for calibration procedures. The model employs a multi-rate explicit time integration scheme to handle varying time scales in multi-physics systems. Through simulations conducted on granite and ceramic materials, this model demonstrates its effectiveness. It successfully simulates thermal damage behavior in granite arising from incompatible mineral expansion and accurately calculates thermal crack propagation in ceramic slabs during quenching. To account for material heterogeneity, the model utilizes the Shuffle algorithm… More >

Chengkan Xu^1,2,4, Xiaofei Wang³, Yixuan Li², Guannan Wang^2,*, He Zhang^2,4,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 957-974, 2024, DOI:10.32604/cmes.2024.047327

Abstract Structural damage in heterogeneous materials typically originates from microstructures where stress concentration occurs. Therefore, evaluating the magnitude and location of localized stress distributions within microstructures under external loading is crucial. Repeating unit cells (RUCs) are commonly used to represent microstructural details and homogenize the effective response of composites. This work develops a machine learning-based micromechanics tool to accurately predict the stress distributions of extracted RUCs. The locally exact homogenization theory efficiently generates the microstructural stresses of RUCs with a wide range of parameters, including volume fraction, fiber/matrix property ratio, fiber shapes, and loading direction. Subsequently, the conditional generative adversarial network… More > Graphic Abstract

Hayder Kareem Sakran^1,2, Mohd Sharizal Abdul Aziz^1,*, Chu Yee Khor³

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 109-137, 2024, DOI:10.32604/cmes.2024.047245

Abstract The centrifugal pump is a prevalent power equipment widely used in different engineering patterns, and the impeller blade wrap angle significantly impacts its performance. A numerical investigation was conducted to analyze the influence of the blade wrap angle on flow characteristics and energy distribution of a centrifugal pump evaluated as a low specific speed with a value of 69. This study investigates six impeller models that possess varying blade wrap angles (95°, 105°, 115°, 125°, 135°, and 145°) that were created while maintaining the same volute and other geometrical characteristics. The investigation of energy loss was conducted to evaluate the… More > Graphic Abstract

YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB^*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

LIJUAN ZHANG^1,#, QINGYIN MENG^2,#, LI ZHUANG¹, QUAN GONG¹, XIANDA HUANG³, XUEQIN LI¹, SHIJUAN LI¹, GUOQIN WANG⁴, XICAI WANG^5,*

BIOCELL, Vol.48, No.4, pp. 581-590, 2024, DOI:10.32604/biocell.2024.047260

Abstract Background: Lung adenocarcinoma is a very pervasive histological form of lung cancers, and inhibiting metastasis is crucial for effective treatment. In this investigation, we explored the functional interaction of miR-30a-5p and the putative transcription factor 2 of the homeodomain (PHTF2) in dictating the aggressiveness and metastasis of lung adenocarcinoma. Method: We collected clinical samples to evaluate the expression patterns of miR-30a-5p and PHTF2 in lung adenocarcinoma along with normal tissues. Cellular experiments including cell count kit (CCK)-8 growth assay, apoptosis analysis, migration and invasion examinations were performed to assess the aggressiveness of lung adenocarcinoma cells. Furthermore, we examined tumorigenesis and… More > Graphic Abstract

JIYU WANG^1,2, HUIXIA LI^1,2, DEYUAN ZHOU^1,2, LIHONG BAI^1,2, KEJING TANG^1,2,3,*

BIOCELL, Vol.48, No.4, pp. 623-637, 2024, DOI:10.32604/biocell.2024.030420

Abstract Background: For patients with lung cancer, timely identification of new lung lesions as infectious or non-infectious, and accurate identification of pathogens is very important in improving OS of patients. As a new auxiliary examination, metagenomic next-generation sequencing (mNGS) is believed to be more accurate in diagnosing infectious diseases in patients without underlying diseases, compared with conventional microbial tests (CMTs). We designed this study to find out whether mNGS has better performance in distinguishing infectious and non-infectious diseases in lung cancer patients using bronchoalveolar lavage fluid (BALF). Materials and Methods: This study was a real-world retrospective review based on electronic medical… More >

Umer Nauman¹, Yuhong Zhang², Zhihui Li³, Tong Zhen^1,3,*

Journal of Intelligent Medicine and Healthcare, Vol.2, pp. 15-34, 2024, DOI:10.32604/jimh.2024.048784

Abstract The convergence of handheld devices and cloud-based computing has transformed how Electronic Health Records (EHRs) are stored in mobile cloud paradigms, offering benefits such as affordability, adaptability, and portability. However, it also introduces challenges regarding network security and data confidentiality, as it aims to exchange EHRs among mobile users while maintaining high levels of security. This study proposes an innovative blockchain-based solution to these issues and presents secure cloud storage for healthcare data. To provide enhanced cryptography, the proposed method combines an enhanced Blowfish encryption method with a new key generation technique called Elephant Herding Optimization with Resistance-Based Training (EHO-RBT).… More >

Laima Vevere^*, Beatrise Sture, Vladimir Yakushin, Mikelis Kirpluks, Ugis Cabulis

Journal of Renewable Materials, Vol.12, No.3, pp. 585-602, 2024, DOI:10.32604/jrm.2024.047350

Abstract Cryogenic insulation material rigid polyurethane (PU) foams were developed using bio-based and recycled feedstock. Polyols obtained from tall oil fatty acids produced as a side stream of wood biomass pulping and recycled polyethylene terephthalate were used to develop rigid PU foam formulations. The 4th generation physical blowing agents with low global warming potential and low ozone depletion potential were used to develop rigid PU foam cryogenic insulation with excellent mechanical and thermal properties. Obtained rigid PU foams had a thermal conductivity coefficient as low as 0.0171 W/m·K and an apparent density of 37–40 kg/m³. The developed rigid PU foams had… More > Graphic Abstract

Dengke Xu¹, Linlin Shen¹, Fangzhong Xu^2,*

International Journal of Mental Health Promotion, Vol.26, No.3, pp. 229-238, 2024, DOI:10.32604/ijmhp.2024.046023

Abstract Based on China Family Panel Studies (CFPS) 2018 data, the multiple linear regression model is used to analyze the effects of Internet use on women’s depression, and to test the robustness of the regression results. At the same time, the effects of Internet use on mental health of women with different residence, age, marital status and physical health status are analyzed. Then, we can obtain that Internet use has a significant promoting effect on women’s mental health, while the degree of Internet use has a significant inhibitory effect on women’s mental health. In addition, the study found that women’s age,… More >