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  • Open Access

    ARTICLE

    Interferon-gamma regulates the progression of neuroblastoma cells through interferon-regulatory factor-1

    JING WANG1,#, JUNFENG XU2,#, YINGRAN YANG1, YOUZHENG QIU1, SHANSHAN ZHANG3, NING WANG1,3,*

    BIOCELL, Vol.48, No.9, pp. 1343-1353, 2024, DOI:10.32604/biocell.2024.051673 - 04 September 2024

    Abstract Objective: This study aimed to elucidate the influence of IFN-gamma (IFN-γ) in neuroblastoma (NB) cells and reveal its potential underlying molecular mechanism. Methods: The Cell Counting Kit-8, Transwell apparatus, and flow cytometry were employed to assess cellular viability, migratory capacity, invasive potential, and apoptotic rates, respectively. RNA-seq combined with bioinformatics analysis revealed differentially expressed genes (DEGs) and their possible biological functions. Protein levels were determined by western blot analysis. Results: IFN-γ treatment resulted in diminished cell viability, mitigated migratory and invasive capabilities, and augmented apoptotic activity in the SK-N-BE (2) cell line, whereas it exhibited the… More >

  • Open Access

    RETRACTION

    Retraction: Gamma Irradiation Upregulates B-cell Translocation Gene 2 to Attenuate Cell Proliferation of Lung Cancer Cells Through the JNK and NF-κB Pathways

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.9, pp. 1527-1527, 2024, DOI:10.32604/or.2024.056120 - 23 August 2024

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Analysis of Progressively Type-II Inverted Generalized Gamma Censored Data and Its Engineering Application

    Refah Alotaibi1, Sanku Dey2, Ahmed Elshahhat3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.1, pp. 459-489, 2024, DOI:10.32604/cmes.2024.053255 - 20 August 2024

    Abstract A novel inverted generalized gamma (IGG) distribution, proposed for data modelling with an upside-down bathtub hazard rate, is considered. In many real-world practical situations, when a researcher wants to conduct a comparative study of the life testing of items based on cost and duration of testing, censoring strategies are frequently used. From this point of view, in the presence of censored data compiled from the most well-known progressively Type-II censoring technique, this study examines different parameters of the IGG distribution. From a classical point of view, the likelihood and product of spacing estimation methods are… More >

  • Open Access

    ARTICLE

    Bioinformatics analysis and experimental validation of cystathionine-gamma-lyase as a potential prognosis biomarker in hepatocellular carcinoma

    YANAN MA1, SHANSHAN WANG2,*, HUIGUO DING1,*

    BIOCELL, Vol.48, No.3, pp. 463-471, 2024, DOI:10.32604/biocell.2024.048244 - 15 March 2024

    Abstract Background: Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis and high mortality worldwide. Although cystathionine-gamma-lyase (CSE) plays an important role in the development of multiple tumors, the clinical implication and potential mechanisms of CSE in HCC development remain elusive. Methods: In our study, the CSE expression in HCC was analyzed in Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) datasets and further confirmed by RT-qPCR and immunohistochemistry assays in HCC samples. Furthermore, the associations between CSE expression and HCC malignancy as well as survival were analyzed in GSE14520 and validated… More >

  • Open Access

    ARTICLE

    Text-to-Sketch Synthesis via Adversarial Network

    Jason Elroy Martis1, Sannidhan Manjaya Shetty2,*, Manas Ranjan Pradhan3, Usha Desai4, Biswaranjan Acharya5,*

    CMC-Computers, Materials & Continua, Vol.76, No.1, pp. 915-938, 2023, DOI:10.32604/cmc.2023.038847 - 08 June 2023

    Abstract In the past, sketches were a standard technique used for recognizing offenders and have remained a valuable tool for law enforcement and social security purposes. However, relying on eyewitness observations can lead to discrepancies in the depictions of the sketch, depending on the experience and skills of the sketch artist. With the emergence of modern technologies such as Generative Adversarial Networks (GANs), generating images using verbal and textual cues is now possible, resulting in more accurate sketch depictions. In this study, we propose an adversarial network that generates human facial sketches using such cues provided More >

  • Open Access

    ARTICLE

    Speech Separation Algorithm Using Gated Recurrent Network Based on Microphone Array

    Xiaoyan Zhao1,*, Lin Zhou2, Yue Xie1, Ying Tong1, Jingang Shi3

    Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 3087-3100, 2023, DOI:10.32604/iasc.2023.030180 - 15 March 2023

    Abstract Speech separation is an active research topic that plays an important role in numerous applications, such as speaker recognition, hearing prosthesis, and autonomous robots. Many algorithms have been put forward to improve separation performance. However, speech separation in reverberant noisy environment is still a challenging task. To address this, a novel speech separation algorithm using gate recurrent unit (GRU) network based on microphone array has been proposed in this paper. The main aim of the proposed algorithm is to improve the separation performance and reduce the computational cost. The proposed algorithm extracts the sub-band steered… More >

  • Open Access

    ARTICLE

    Gamma Correction for Brightness Preservation in Natural Images

    Navleen S Rekhi1,2,*, Jagroop S Sidhu2, Amit Arora2

    Computer Systems Science and Engineering, Vol.44, No.3, pp. 2791-2807, 2023, DOI:10.32604/csse.2023.026976 - 01 August 2022

    Abstract Due to improper acquisition settings and other noise artifacts, the image degraded to yield poor mean preservation in brightness. The simplest way to improve the preservation is the implementation of histogram equalization. Because of over-enhancement, it failed to preserve the mean brightness and produce the poor quality of the image. This paper proposes a multi-scale decomposition for brightness preservation using gamma correction. After transformation to hue, saturation and intensity (HSI) channel, the 2D- discrete wavelet transform decomposed the intensity component into low and high-pass coefficients. At the next phase, gamma correction is used by auto-tuning… More >

  • Open Access

    ARTICLE

    Designing Bayesian Two-Sided Group Chain Sampling Plan for Gamma Prior Distribution

    Waqar Hafeez1, Nazrina Aziz1,2,*

    Computer Systems Science and Engineering, Vol.44, No.2, pp. 1069-1079, 2023, DOI:10.32604/csse.2023.022047 - 15 June 2022

    Abstract Acceptance sampling is used to decide either the whole lot will be accepted or rejected, based on inspection of randomly sampled items from the same lot. As an alternative to traditional sampling plans, it is possible to use Bayesian approaches using previous knowledge on process variation. This study presents a Bayesian two-sided group chain sampling plan (BTSGChSP) by using various combinations of design parameters. In BTSGChSP, inspection is based on preceding as well as succeeding lots. Poisson function is used to derive the probability of lot acceptance based on defective and non-defective products. Gamma distribution… More >

  • Open Access

    ARTICLE

    Gamma Radiation Induced Mutual Grafting of Quaternary Ammonium-Based Monomer on to Rayon Fibers to Improve its Water Absorbency and Antibacterial Efficacy

    SUBRATA PAL1,2, BHUVNESHWAR RAI1, AJAY KUMAR TYAGI1, SUNITA RATTAN2, VIRENDRA KUMAR3

    Journal of Polymer Materials, Vol.39, No.1-2, pp. 55-70, 2022, DOI:10.32381/JPM.2022.39.1-2.4

    Abstract The present work is focused on the study of antimicrobial and water absorption properties of the surface of grafted rayon fiber with quaternary ammonium-based salts containing 3- Acrylamidopropyl trimethyl ammonium chloride (APTAC) monomer induced by gamma radiation. Grafting was qualitatively confirmed by FTIR-ATR,TGA, SEM and by calculating grafting yield and grafting efficiency. The performance was examined for water absorbency and antibacterial efficacy (R) against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Study showed that water absorption, grafting yield and grafting efficiency increased steadily with the increase in monomer concentration and absorbed gamma irradiation More >

  • Open Access

    CASE REPORT

    Delayed Bilateral, Post-Traumatic Extra-Subdural Hematomas in a Patient with Meningioma

    Giuseppe Emmanuele Umana1,*, Gianluca Ferini2, Antonio Crea1, Bipin Chaurasia3, Vishal Chavda4, Leonardo Corbino1, Daniele Franceschini1, Maria Grazia Tranchina5, Marco Fricia1, Francesca Graziano6, Giovanni Federico Nicoletti6, Salvatore Cicero1, Gianluca Scalia6

    Oncologie, Vol.24, No.2, pp. 341-348, 2022, DOI:10.32604/oncologie.2022.021347 - 29 June 2022

    Abstract Concomitant acute epidural hematoma (EDH) and subdural hematoma (SDH) is a rare finding, and its bilateral onset has not yet been reported in literature. We present the first report of a patient affected by post-traumatic concomitant EDH and SDH, with the contralateral, delayed onset of another, associated with meningioma previously treated with gamma knife. A 60-year-old female patient with a history of simple focal seizures with motor symptoms and well-controlled by drugs since childhood, arterial hypertension, and incidental diagnosis of multiple meningiomas was referred to our department after falling down the stairs. Initially, the patient… More >

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