Ali Abdullah Abbas Baiee, Sasan Asiaei^*, Sayed Mostafa Hosseinalipour^*

Frontiers in Heat and Mass Transfer, Vol.22, No.3, pp. 955-976, 2024, DOI:10.32604/fhmt.2024.051532

Abstract Globally, potable water scarcity is pervasive problem. The solar distillation device is a straightforward apparatus that has been purposefully engineered to convert non-potable water into potable water. The experimental study is distinctive due to the implementation of a rotational mechanism within the pyramidal solar still (PSS), which serves to enhance the evaporation and condensation processes. The objective of this research study is to examine the impact of integrating rotational motion into pyramidal solar stills on various processes: water distillation, evaporation, condensation, heat transfer, and energy waste reduction, shadow effects, and low water temperature in saline… More >

LINGLI ZHANG^1,2,#, YAN LI^1,#, JINGXIN MAO^1,*

BIOCELL, Vol.48, No.6, pp. 905-922, 2024, DOI:10.32604/biocell.2024.050396

Abstract Hepatocellular carcinoma (HCC) remains a prevalent and challenging malignancy globally, characterized by its numerous causal factors and generally unfavorable prognosis. In the relentless pursuit of effective treatment modalities, natural products have emerged as a promising and relatively non-toxic alternative, garnering significant interest. The integration of natural products with contemporary medical research has yielded encouraging therapeutic outcomes in the management of HCC. This review offers a comprehensive overview of the causal factors underlying HCC, and the diverse treatment options available, and highlights the advancements made by natural products in anti-HCC research. Particularly, we provide an outline More >

LITING WEN^#, XIAOXIA ZENG^#, PEIXIONG CHEN, DAPENG ZHAO, YANGYANG LI, XIANHAI ZENG^*

BIOCELL, Vol.48, No.6, pp. 991-999, 2024, DOI:10.32604/biocell.2024.050219

Abstract Background: Cochlear hair cell injury is a common pathological feature of hearing loss. The basic helix-loop-helix family, member e40 (Bhlhe40), a gene belonging to the basic helix-loop-helix (bHLH) family, exhibits strong transcriptional repression activity. Methods: Oxidative damage, in House Ear Institute-Organ of Corti 1 (HEI‑OC1) cells, was caused using hydrogen peroxide (HO). The Ad-Bhlhe40 particles were constructed to overexpress Bhlhe40 in HEI-OC1 cells. Various assays including cell counting kit-8 (CCK-8), terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling assay (TUNEL), flow cytometry, immunofluorescence, and corresponding commercial kits were employed to investigate the impacts of Bhlhe40 on cell viability, apoptosis,… More > Graphic Abstract

Maitham A. Khajah, Princy M. Mathew, Yunus A. Luqmani

Oncology Research, Vol.25, No.8, pp. 1283-1295, 2017, DOI:10.3727/096504017X14883245308282

Abstract Current mainstream pharmacological options for the treatment of endocrine-resistant breast cancer have limitations in terms of their side effect profile and lack of discrimination between normal and cancer cells. In the current study, we assessed the responses of normal breast epithelial cells MCF10A, estrogen receptorpositive (ER+ ) MCF-7, and ER-silenced pII breast cancer cells to inhibitors (either individually or in combination) of downstream signaling molecules. The expression/activity of ERK1/2, p38 MAPK, and Akt was determined by Western blotting. Cell proliferation, motility, and invasion were determined using MTT, wound healing, and Matrigel assays, respectively. Morphological changes… More >

Ruchun Jia¹, Jianwei Zhang^1,*, Yi Lin¹, Yunxiang Han¹, Feike Yang²

CMC-Computers, Materials & Continua, Vol.79, No.2, pp. 2523-2546, 2024, DOI:10.32604/cmc.2024.047543

Abstract In order to enhance the accuracy of Air Traffic Control (ATC) cybersecurity attack detection, in this paper, a new clustering detection method is designed for air traffic control network security attacks. The feature set for ATC cybersecurity attacks is constructed by setting the feature states, adding recursive features, and determining the feature criticality. The expected information gain and entropy of the feature data are computed to determine the information gain of the feature data and reduce the interference of similar feature data. An autoencoder is introduced into the AI (artificial intelligence) algorithm to encode and… More >

Guangwei Sun^1,2,#, Xuanhao Zhang^3,#, Yi Liu³, Liguang Chai², Daisong Liu², Zhenguo Chen^1,*, Shiyou Lü^3,*

Phyton-International Journal of Experimental Botany, Vol.93, No.4, pp. 641-659, 2024, DOI:10.32604/phyton.2024.049285

Abstract The Nicotiana genus, commonly known as tobacco, holds significant importance as a crucial economic crop. Confronted with an abundance of herbivorous insects that pose a substantial threat to yield, tobacco has developed a diverse and sophisticated array of mechanisms, establishing itself as a model of plant ecological defense. This review provides a concise overview of the current understanding of tobacco’s defense strategies against herbivores. Direct defenses, exemplified by its well-known tactic of secreting the alkaloid nicotine, serve as a potent toxin against a broad spectrum of herbivorous pests. Moreover, in response to herbivore attacks, tobacco enhances… More >

SAIFEI XIE^1,2,4, HUI XIE^2,*, JINCAI GUO³, JIN TAN⁴, YULIN YU¹, MINYI ZHANG¹, SHANG WEN¹

BIOCELL, Vol.48, No.4, pp. 591-599, 2024, DOI:10.32604/biocell.2024.046691

Abstract Background: Puerarin (Pue) has been reported to be a natural active ingredient with multiple antifibrotic properties. This work aimed at exploring the function of Pue in oral submucous fibrosis (OSF) treatment. Methods: Human oral mucosa fibroblasts (hOMF) were induced with transforming growth factor beta1 (TGF-β1) and intervened with Pue. Expressions of fibrosis-related markers were analyzed by Western blot and IF staining. Cell viability was characterized by the CCK-8 assay. Expressions of miR-30 family members were quantified by qRT-PCR. The correlation between fibroblast activation protein (FAP) and miR-30 family expression was evaluated by the Pearson correlation… More > Graphic Abstract

Bing Liu¹, Zhe Zhang¹, Shengrong Hu², Song Sun^3,*, Dapeng Liu⁴, Zhenyu Qiu⁵

CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 4049-4069, 2024, DOI:10.32604/cmc.2024.048099

Abstract Internet of Things (IoT) is vulnerable to data-tampering (DT) attacks. Due to resource limitations, many anomaly detection systems (ADSs) for IoT have high false positive rates when detecting DT attacks. This leads to the misreporting of normal data, which will impact the normal operation of IoT. To mitigate the impact caused by the high false positive rate of ADS, this paper proposes an ADS management scheme for clustered IoT. First, we model the data transmission and anomaly detection in clustered IoT. Then, the operation strategy of the clustered IoT is formulated as the running probabilities… More >

Hosam Alhakami^*

CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 329-356, 2024, DOI:10.32604/cmc.2023.043439

Abstract The rapid growth of the Internet of Things (IoT) operations has necessitated the incorporation of quantum computing technologies to meet its expanding needs. This integration is motivated by the need to solve the specific issues provided by the expansion of IoT and the potential benefits that quantum computing can offer in this scenario. The combination of IoT and quantum computing creates new privacy and security problems. This study examines the critical need to prevent potential security concerns from quantum computing in IoT applications. We investigate the incorporation of quantum computing approaches within IoT security frameworks,… More >

Qin Yao, Yida Zeng^*, Qingui Jia

Energy Engineering, Vol.121, No.1, pp. 221-241, 2024, DOI:10.32604/ee.2023.041028

Abstract In recent years, switched inductor (SL) technology, switched capacitor (SC) technology, and switched inductor-capacitor (SL-SC) technology have been widely applied to optimize and improve DC-DC boost converters, which can effectively enhance voltage gain and reduce device stress. To address the issue of low output voltage in current renewable energy power generation systems, this study proposes a novel non-isolated cubic high-gain DC-DC converter based on the traditional quadratic DC-DC boost converter by incorporating a SC and a SL-SC unit. Firstly, the proposed converter’s details are elaborated, including its topology structure, operating mode, voltage gain, device stress,… More >