Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (2)
  • Open Access

    ARTICLE

    Response of the Ginseng C2H2-Type Zinc Finger Protein Family PgZFPs Gene to Methyl Jasmonate Regulation

    Yue Jiang1,2,#, Lingyu Liu1,#, Kangyu Wang1,2, Mingzhu Zhao1,2, Ping Chen1,2, Jun Lei1,2, Yanfang Wang3, Meiping Zhang1,2, Yi Wang1,2,*, Guang Chen1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.11, pp. 3055-3071, 2024, DOI:10.32604/phyton.2024.056384 - 30 November 2024

    Abstract The main active components of ginseng are ginsenosides, which play significant roles in treating cardiovascular diseases, cancer, and providing antioxidant effects. Ginsenosides are primarily synthesized through the mevalonate pathway and the methylerythritol phosphate pathway. Many key enzyme genes involved in this biosynthetic process have been cloned and validated, yet the regulatory functions of transcription factors remain unclear. The C2H2-type zinc finger protein family, one of the largest families of transcription factors, is crucial in plant growth and development, response to biotic and abiotic stresses, and regulation of secondary metabolism. This study, based on the ginseng transcriptome More >

  • Open Access

    ARTICLE

    Functional study of TNF-α promoter polymorphisms: literature review and meta-analysis

    Arsene Mekinian1, Ryad Tamouza2, Stephan Pavy3, Nicolas Gestermann1, Marc Ittah1, Xavier Mariette1,3, Corinne Miceli-Richard1,3

    European Cytokine Network, Vol.22, No.2, pp. 88-102, 2011, DOI:10.1684/ecn.2011.0285

    Abstract The functional consequences of TNF-α promoter SNPs are still controversial and, to date, the functional consequences of TNF-α haplotype combinations in healthy subjects have not been assessed. In order to assess functional consequences of each TNF-α polymorphism and of their haplotype combination, TNF-α expression and secretion by LPS-stimulated monocytes from 50 healthy subjects were assessed. Monocytes were isolated and cultured for four hours, after 100 ng/mL LPS stimulation. mRNA expression was quantified using the real-time polymerase chain reaction, and TNF-α levels were measured by enzyme-linked immunosorbent assay. Each subject was genotyped for TNF-α -857 C/T,… More >

Displaying 1-10 on page 1 of 2. Per Page