Xiaoli You1,2,3,, Ruiyu Bai1,2,3,4,, Kai Xue1,2,3, Zimo Zhang1,2,3, Minghao Wang5, Xuanqi Wang1,2,3, Jiahao Wang1,2,3, Jinku Guo1,2, Qiang Shen3, Honglong Chang3, Xu Long6,*, Bowen Ji1,2,3,*
CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1205-1231, 2024, DOI:10.32604/cmes.2024.049047
Abstract Implanted neural probes can detect weak discharges of neurons in the brain by piercing soft brain tissue, thus as important tools for brain science research, as well as diagnosis and treatment of brain diseases. However, the rigid neural probes, such as Utah arrays, Michigan probes, and metal microfilament electrodes, are mechanically unmatched with brain tissue and are prone to rejection and glial scarring after implantation, which leads to a significant degradation in the signal quality with the implantation time. In recent years, flexible neural electrodes are rapidly developed with less damage to biological tissues, excellent… More >
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