Lili Liu¹, Can Hu⁴, Huilin Cheng¹, Chuangju Ma¹, Jiancheng Sun¹, Yunyi Chen², Manxi Wu², Han Yang², Cui Sun^2,3, Jinping Cao^2,3, Dengliang Wang^1,*, Yue Wang^2,*, Chongde Sun^2,3

Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2499-2518, 2024, DOI:10.32604/phyton.2024.054449 - 30 September 2024

Abstract Oral ulcers, a common mucosal affliction, severely diminish patients’ quality of life due to pain and discomfort. Despite existing treatments, the frequent recurrence of oral ulcers underscores the need for more effective therapeutic options. This study aimed to investigate the inhibitory effects of Ponkan (Citrus reticulata ‘Ponkan’) extracts and their flavonoid components on oral ulcers, exploring their potential as a natural therapy. Twenty different Ponkan cultivars were selected for flavonoid extraction and analysis. Ultra-performance liquid chromatography (UPLC) and high-resolution mass spectrometry (HRMS) were utilized for substance identification, leading to the discovery of 16 flavonoid compounds. Using… More > Graphic Abstract

Fenglan Zhao^1,2,#, Shuwen Wu^1,#, Xue Meng¹, Jianping Xue^1,2, Yongbo Duan^1,2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1705-1716, 2024, DOI:10.32604/phyton.2024.052287 - 30 July 2024

Abstract Dōng líng căo, the dried aboveground parts of Isodon rubescens (Hemls.) Hara., is commonly consumed as a medicinal decoction or tea beverage. Natural beverages can be an important source of human dietary selenium (Se). However, how I. rubescens plants respond to exogenous Se remains unknown. In this study, a pot cultivation experiment was employed to investigate the phenotypic and physiological responses of I. rubescens plants exposed to Se. Fifteen days after applying different concentrations of sodium selenate to the soil, the Se enrichment capacity, growth indices, antioxidant capacities, and the content of flavonoids and diterpenoids were measured in… More >

Antonio Pizzi^1,*, Marie-Pierre Laborie^2,3, Zeki Candan⁴

Journal of Renewable Materials, Vol.12, No.3, pp. 397-425, 2024, DOI:10.32604/jrm.2023.046074 - 11 April 2024

Abstract Condensed and hydrolysable tannins are non-toxic natural polyphenols that are a commercial commodity industrialized for tanning hides to obtain leather and for a growing number of other industrial applications mainly to substitute petroleum-based products. They are a definite class of sustainable materials of the forestry industry. They have been in operation for hundreds of years to manufacture leather and now for a growing number of applications in a variety of other industries, such as wood adhesives, metal coating, pharmaceutical/medical applications and several others. This review presents the main sources, either already or potentially commercial of More > Graphic Abstract

Khalid Rehman Hakeem^1,2,3,*, Hesham F. Alharby¹, M. Irfan Qureshi⁴

Phyton-International Journal of Experimental Botany, Vol.92, No.12, pp. 3323-3344, 2023, DOI:10.32604/phyton.2023.030212 - 28 December 2023

Abstract

Abiotic stresses, including drought, have been found to affect the growth and medicinal quality of numerous herbs. The proposed study aims to study the effects of different drought regimes on the metabolic profile, growth, ecophysiology, cellular antioxidants, and antioxidant potential of Nigella sativa (Black cumin) leaf. Forty-day-old seedlings of N. sativa were exposed to three regimes of drought (control, moderate and high) for a week. UPLC-MS/MS metabolic profile of the leaf reveals the presence of more than a hundred metabolites belonging to anthocyanins, chalcones, dihydro flavonoids, flavonoids, flavanols, flavones, flavonoid carbonoside, isoflavones, etc. Drought was found to

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Laura Isabel Arias-Rodríguez¹, Martha Alicia Rodríguez-Mendiola^2,*, Carlos Arias-Castro^2,*, Federico Antonio Gutiérrez Miceli¹, Diana Reséndez Pérez³, María Celina Luján Hidalgo¹, Juan José Villalobos Maldonado¹, Norma Alejandra Mancilla Margalli²

Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2807-2823, 2023, DOI:10.32604/phyton.2023.030396 - 15 September 2023

Abstract In recent years, there has been a growing interest in exploring alternative treatments for bone defects. Bone tissue engineering has turned its attention to plant extracts containing osteogenic flavonoids as potential promoters of bone regeneration. In our study, we specifically investigated the extract of Petroselinum crispum, a plant known for its abundance of osteogenic flavonoids such as apigenin, quercetin, and kaempferol. Our objective was to compare the total flavonoid content (TFC) and their accumulation in different sources. We obtained hydrolyzed aqueous extracts from the leaves of parsley plants (grown for 12 weeks in the field), weekly… More >

FU-MING TSAI¹, PING-HSUN LU^2,3, LU-KAI WANG⁴, CHAN-YEN KUO¹, MAO-LIANG CHEN¹, CHUN-HUA WANG^5,6,*

BIOCELL, Vol.47, No.8, pp. 1793-1802, 2023, DOI:10.32604/biocell.2023.030093 - 28 August 2023

Abstract Background: Cisplatin is a chemotherapeutic agent commonly used clinically for the treatment of various human cancers. Patients often reduce the use of cisplatin due to its side effects, which in turn affects its treatment. This study explored the mechanism of action of safflower extract as an adjuvant traditional Chinese medicine for chemotherapy. Methods: Primary human follicle dermal papilla cells (HFDPCs) were used as target cells for cisplatin-induced damage to hair cells. Western blotting was used to investigate the molecular targets of cisplatin and safflower extract in causing HFDPCs damage. Cell survival and cell cycle were… More >

Yu Zai^*, Shaohua Liu

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 225-236, 2023, DOI:10.32604/phyton.2022.022576 - 06 September 2022

Abstract Kosteletzkya virginica (K. virginica) is used for revegetation of salt-affected coastal tidal flats and as a raw material of biodiesel. K. virginica root tuber, a biowaste with low economic value, is rich in bioactive compounds. This study aimed to extract and identify flavonoids from K. virginica root tubers. The optimal extraction conditions were 1/25 (w/v) solid/liquid ratio, 40% ethanol concentration at 40°C for 60 min. Under these conditions, 65.2 ± 3.7 mg/g total flavonoid content was extracted from the roots, which were collected from salinized soil in late autumn of the third year. Antioxidant activity was evaluated through 1,1-diphenyl-2-picrylhydrazyl, More >

Yanzhao Zhang^*, Chenyang Yu, Xi Lu, Yanwei Cheng

Phyton-International Journal of Experimental Botany, Vol.91, No.11, pp. 2505-2518, 2022, DOI:10.32604/phyton.2022.021455 - 12 July 2022

Abstract Tree peony cultivars with yellow flowers are rare and valuable, but the molecular mechanism of pigment accumulation is not clear. In this study, the petal transcriptome of three developmental stages were sequenced to determine the differentially expressed genes (DEGs) regulating yellow flowers color. The results showed that 10,842 and 12,022 DEGs were screened in stage 1 vs. stage 2 and in stage 2 vs. stage 3, respectively. Through analysis of flavonoid structural genes (FSGs), we found that the transcription level of DFR was very low in the three developmental stages. In a small group of cultivars, the… More >

ZHIMEI TANG, QIANG ZHANG^*

BIOCELL, Vol.46, No.2, pp. 357-366, 2022, DOI:10.32604/biocell.2022.015958 - 20 October 2021

Abstract Flavonoids are a class of phytochemical molecules abundant in many plants, fruits, vegetables, and leaves. Flavonoids possess a series of significant biological activities, including anticancer, antioxidant, antiviral, and antiinflammatory properties. They become an important source of dietary supplements and natural health products. Though many studies confirmed the safety of flavonoids, the potential toxicity of flavonoids is still a remarkable field of research to be explored. The enthusiasm for flavonoids expressed by the public has sometimes overlooked their toxicity and also consumed the flavonoids exceeding the body requirements. The current review focused on the potential toxicity… More >

JIANFEI GAO¹, KANGNING XIONG^2,*, WEIJIE LI¹, WEI ZHOU³

BIOCELL, Vol.46, No.1, pp. 285-296, 2022, DOI:10.32604/biocell.2021.016253 - 29 September 2021

Abstract Kadsura coccinea (Lem.) is a woody wine plant with a peculiar fruit enriched in important health-promoting compounds. The non-editable part of the fruit, i.e., the seed and peel, represents more than 60% of the fruit and is considered a biowaste. This significantly restricts the development of the K. coccinea fruit industry. Clarifying the metabolic components of the different fruit parts can help to improve the utilization rate and valorization of K. coccinea. Herein, we evaluated K. coccinea fruit peel, pulp, and seed using widely-targeted metabolomics and quantified a set of 736 bioactive compounds from 11 major metabolite classes. The… More >