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    ARTICLE

    More than the heart: Hepatic, renal, and cardiac dysfunction in adult Fontan patients

    Ryan D. Byrne1, Angela J. Weingarten2, Daniel E. Clark2, Shi Huang3, Roman E. Perri4, Andrew E. Scanga4, Jonathan N. Menachem2, Larry W. Markham5, Benjamin P. Frischhertz2

    Congenital Heart Disease, Vol.14, No.5, pp. 765-771, 2019, DOI:10.1111/chd.12820

    Abstract Setting: Fontan‐associated liver disease universally affects adults with single ventricle heart disease. Chronic kidney disease is also highly prevalent in adult Fontan patients. In this study, we evaluate the relationship of Fontan hemodynamics invasively and noninvasively with extra‐cardiac dysfunction as measured by MELD and MELD‐XI.
    Objective: We hypothesize that invasive and noninvasive measures of Fontan circuit congestion and ventricular dysfunction are associated with increased MELD and MELD‐XI scores.
    Design: Single‐center data from adults with Fontan palliation who had ongoing care, including cardiac catheterization, were retrospectively collected. Hemodynamic data from cardiac catheterization and echocardiographic assessment of ventricular and atrioventricular… More >

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