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  • Open Access

    ARTICLE

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

    JIAN TANG1, CHENQIANG ZHU1, YUN CHEN1, YUNLONG WU1, MING HE1, YI ZHOU2, MINGHUA XIE2,*

    BIOCELL, Vol.48, No.4, pp. 639-651, 2024, DOI:10.32604/biocell.2024.047562

    Abstract Background: The specific impact of sphingolipid metabolism on developing hepatocellular Carcinoma (HCC) remains unclear. This study aims to explore the relationship between sphingolipid metabolism and HCC prognosis, immune response, and drug sensitivity. Methods: Data were obtained from The Cancer Genome Atlas (TCGA)-Hepatocellular Carcinoma (LIHC) and Gene Expression Omnibus (GEO, GSE14520 datasets). 47 sphingolipid metabolism genes were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. After classifying HCC samples using the Non-negative Matrix Factorization (NMF) clustering method, differentially expressed genes were screened. Then, 8 risk genes were obtained by univariate analysis, survival random forest reduction and lasso analysis.… More > Graphic Abstract

    Identification prognostic features related to sphingolipid metabolism and experimental validation of TRIM47 in hepatocellular carcinoma

  • Open Access

    ARTICLE

    An Experimental Study and Analysis of Different Dielectrics in Electrical Discharge Machining of Al 6063 Alloy

    B. MOULIPRASANTHA, P. HARIHARANB

    Journal of Polymer Materials, Vol.36, No.4, pp. 351-369, 2019, DOI:10.32381/JPM.2019.36.04.5

    Abstract Electrical discharge machining is a non-traditional machining processes in which it is based upon thermal and electrical energy source as an interval energy pulse discharge in-between the work piece and tool electrode so as to remove the material. A systematical investigation of melting and vaporising of aluminium to find the output responses such as Material removal rate (MRR), Electrode wear rate (Ra), and Surface finish (EWR) in EDM using two different dielectrics was conducted as experimental work. The working fluids are Polyethylene glycol (PEG 600) and kerosene. It is the hour of need to get the maximum MRR and surface… More >

  • Open Access

    ARTICLE

    Experimental Novel Investigation of Electrostatic Charged Multi Walled Carbon Nanotubes Reinforced Epoxy Based Polymer Composite

    R. SARAVANAN*, A. SURESHBABU

    Journal of Polymer Materials, Vol.37, No.1-2, pp. 43-54, 2020, DOI:10.32381/JPM.2020.37.1-2.4

    Abstract In this research work, multi walled carbon nanotubes (MWCNT) particulate filler of various (0.9, 1.2, 1.5, & 1.8 wt %) weight percentage was used along with epoxy resin. A novel method of distributing the MWCNT in epoxy had been employed to reduce the agglomeration problem by charging the MWCNT electrostatically. The electrostatic charged (MWCNT) and uncharged (MWCNT) were loaded on to matrix and then it was stirred by a mechanical mixer for 300 minutes continuously to achieve uniform distribution. The nano filler reinforced composite was fabricated by using hand layup method and mechanical testing (Tensile and Flexural) were performed as… More >

  • Open Access

    ARTICLE

    Taguchi Design of the Experimental approach to Increase the Biomass and Cell Wall Chitosan Contents of Zygomycetous Dimorphic Fungus Benjaminiella Poitrasii

    S.R. MANE1,2, E. K. PATHAN3, G. PATIL4, S. G. TUPE5, V. GHORMADE4, B. P. CHAUDHARI1,2, M.V. DESHPANDE5,*

    Journal of Polymer Materials, Vol.38, No.3-4, pp. 219-230, 2021, DOI:10.32381/JPM.2021.38.3-4.4

    Abstract A dimorphic fungus Benjaminiella poitrasii contains high chitin/chitosan (35% of the cell wall) in the mycelial (M) form than its yeast (Y) form (20% of the cell wall). However, the relative proportion of chitosan is more in yeast form cells (chitosan: chitin ratio, 6:1) than mycelial cells (chitosan: chitin ratio, 3:1). Using the Taguchi design of experimental (DOE) approach, interactions among eight different parameters showed that carbon source (starch, 10 g/L), incubation time (48 h), inoculum (M and Y mixed 10%), yeast extract (6 g/L) and peptone (10 g/L), were optimum for maximum biomass production. Under these conditions, the chitosan… More >

  • Open Access

    ARTICLE

    Experimental Analysis of Radial Centrifugal Pump Shutdown

    Xiao Sun1, Jiangbo Tong1, Yuliang Zhang2,*, Haibing Cai3, Wen Zhou4, Xiaoqi Jia5, Litao Ou6

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.4, pp. 725-737, 2024, DOI:10.32604/fdmp.2023.045541

    Abstract Centrifugal pumps are widely used in the metallurgy, coal, and building sectors. In order to study the hydraulic characteristics of a closed impeller centrifugal pump during its shutdown in the so-called power frequency and frequency conversion modes, experiments were carried to determine the characteristic evolution of parameters such as speed, inlet and outlet pressure, head, flow rate and shaft power. A quasi-steady-state method was also used to further investigate these transient behaviors. The results show that, compared to the power frequency input, the performance parameter curves for the frequency conversion input are less volatile and smoother. The characteristic time is… More >

  • Open Access

    ARTICLE

    Experimental Study of the Effect of Water Salinity on the Parameters of an Equilibrium Droplet Cluster Levitating over a Water Layer

    Alexander A. Fedorets1, Eduard E. Kolmakov1, Leonid A. Dombrovsky1,2,3,*

    Frontiers in Heat and Mass Transfer, Vol.22, No.1, pp. 1-14, 2024, DOI:10.32604/fhmt.2024.049335

    Abstract New experimental results, which are important for the potential use of small levitating droplets as biochemical microreactors, are reported. It is shown that the combination of infrared heating and reduced evaporation of saline water under the droplet cluster is sufficient to produce equilibrium saltwater droplets over a wide temperature range. The resulting universal dependence of droplet size on temperature simplifies the choice of optimal conditions for generating stable droplet clusters with droplets of the desired size. A physical analysis of the experimental results on the equilibrium size of saltwater droplets makes it possible to separate the effects related to the… More > Graphic Abstract

    Experimental Study of the Effect of Water Salinity on the Parameters of an Equilibrium Droplet Cluster Levitating over a Water Layer

  • Open Access

    ARTICLE

    Experimental Study of Heat Transfer in an Insulated Local Heated from Below and Comparison with Simulation by Lattice Boltzmann Method

    Noureddine Abouricha1,*, Ayoub Gounni2, Mustapha El Alami2

    Frontiers in Heat and Mass Transfer, Vol.22, No.1, pp. 359-375, 2024, DOI:10.32604/fhmt.2024.047632

    Abstract In this paper, experimental and numerical studies of heat transfer in a test local of side heated from below are presented and compared. All the walls, the rest of the floor and the ceiling are made from plywood and polystyrene in sandwich form ( plywood- polystyrene- plywood) just on one of the vertical walls contained a glazed door (). This local is heated during two heating cycles by a square plate of iron the width , which represents the heat source, its temperature is controlled. The plate is heated for two cycles by an adjustable set-point heat source placed just… More >

  • Open Access

    ARTICLE

    Experimental Investigation of a Phase-Change Material’s Stabilizing Role in a Pilot of Smart Salt-Gradient Solar Ponds

    Karim Choubani1,2,*, Ons Ghriss3, Nashmi H. Alrasheedi1, Sirin Dhaoui2, Abdallah Bouabidi2

    Frontiers in Heat and Mass Transfer, Vol.22, No.1, pp. 341-358, 2024, DOI:10.32604/fhmt.2024.047016

    Abstract Faced with the world’s environmental and energy-related challenges, researchers are turning to innovative, sustainable and intelligent solutions to produce, store, and distribute energy. This work explores the trend of using a smart sensor to monitor the stability and efficiency of a salt-gradient solar pond. Several studies have been conducted to improve the thermal efficiency of salt-gradient solar ponds by introducing other materials. This study investigates the thermal and salinity behaviors of a pilot of smart salt-gradient solar ponds with (SGSP) and without (SGSPP) paraffin wax (PW) as a phase-change material (PCM). Temperature and salinity were measured experimentally using a smart… More >

  • Open Access

    ARTICLE

    Experimental and Numerical Study on the Transient Flow Behavior in Gasoline Refueling System

    Chenlin Zhu1, Yan Zhao1, Zhitao Jiang1, Jiafeng Xie3, Lifang Zeng2,*, Lijuan Qian1,*

    Frontiers in Heat and Mass Transfer, Vol.22, No.1, pp. 107-127, 2024, DOI:10.32604/fhmt.2023.044433

    Abstract Efficient and secure refueling within the vehicle refueling systems exhibits a close correlation with the issues concerning fuel backflow and gasoline evaporation. This paper investigates the transient flow behavior in fuel hose refilling and simplified tank fuel replenishment using the volume of fluid method. The numerical simulation is validated with the simplified hose refilling experiment and the evaporation simulation of Stefan tube. The effects of injection flow rate and injection directions have been discussed in the fuel hose refilling part. For both the experiment and simulation, the pressure at the end of the refueling pipe in the lower located nozzle… More >

  • Open Access

    ARTICLE

    EXPERIMENTAL STUDY OF ENHANCED NUCLEATE BOILING HEAT TRANSFER ON UNIFORM AND MODULATED POROUS STRUCTURES

    Calvin Hong Lia, G. P. Petersonb,*

    Frontiers in Heat and Mass Transfer, Vol.1, No.2, pp. 1-10, 2010, DOI:10.5098/hmt.v1.2.3007

    Abstract An experimental investigation of the Critical Heat Flux (CHF) and heat transfer coefficient (HTC) of two-phase heat transfer of de-Ionized (DI) water, pool boiling was conducted using several kinds of sintered copper microparticle porous uniform and modulated structures. The modulated porous structure reached a heat flux of 450 W/cm2 and a heat transfer coefficient of 230,000 W/m2K. The thick and thin uniform porous structures achieved CHFs of 290 W/cm2 and 227 W/cm2 , respectively, and heat transfer coefficients of 118,000 W/m2K and 104,000 W/m2K. The mechanisms for the dramatically improved CHFs and HTCs were identified with assistance of a visualization… More >

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