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  • Open Access

    REVIEW

    Distribution, Etiology, Molecular Genetics and Management Perspectives of Northern Corn Leaf Blight of Maize (Zea mays L.)

    M. Ashraf Ahangar1, Shabir Hussain Wani1,*, Zahoor A. Dar2, Jan Roohi1, Fayaz Mohiddin1, Monika Bansal3, Mukesh Choudhary4, Sumit K. Aggarwal4, S. A. Waza1, Khursheed Ahmad Dar5, Ayman El Sabagh6,7, Celaleddin Barutcular8, Omer Konuşkan9, Mohammad Anwar Hossain10,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.10, pp. 2111-2133, 2022, DOI:10.32604/phyton.2022.020721 - 30 May 2022

    Abstract Maize is cultivated extensively throughout the world and has the highest production among cereals. However, Northern corn leaf blight (NCLB) disease caused by Exherohilum turcicum, is the most devastating limiting factor of maize production. The disease causes immense losses to corn yield if it develops prior or during the tasseling and silking stages of crop development. It has a worldwide distribution and its development is favoured by cool to moderate temperatures with high relative humidity. The prevalence of the disease has increased in recent years and new races of the pathogen have been reported worldwide. The… More >

  • Open Access

    ARTICLE

    Intelligent Approach for Clustering Mutations’ Nature of COVID-19 Genome

    Ankur Dumka1, Parag Verma2, Rajesh Singh3, Anuj Bhardwaj4, Khalid Alsubhi5, Divya Anand6,7,*, Irene Delgado Noya7,8, Silvia Aparicio Obregon7,9

    CMC-Computers, Materials & Continua, Vol.72, No.3, pp. 4453-4466, 2022, DOI:10.32604/cmc.2022.023974 - 21 April 2022

    Abstract In December 2019, a group of people in Wuhan city of Hubei province of China were found to be affected by an infection called dark etiology pneumonia. The outbreak of this pneumonia infection was declared a deadly disease by the China Center for Disease Control and Prevention on January 9, 2020, named Novel Coronavirus 2019 (nCoV-2019). This nCoV-2019 is now known as COVID-19. There is a big list of infections of this coronavirus which is present in the form of a big family. This virus can cause several diseases that usually develop with a serious… More >

  • Open Access

    ARTICLE

    A Retrospective Analysis of 94 Patients with Hemophagocytic Lymphohistiocytosis of Unknown Etiology from a Single Center

    Xiaodan He, Jingshi Wang, Zhao Wang*

    Oncologie, Vol.23, No.4, pp. 559-567, 2021, DOI:10.32604/oncologie.2021.018647 - 31 December 2021

    Abstract Despite extensive work-ups, some patients have been diagnosed with hemophagocytic lymphohistiocytosis (HLH) of unknown etiology. For HLH of unknown etiology, to investigate the clinical features and the factors that may affect the prognosis, we retrospectively reviewed the medical records of 94 patients hospitalized from January 2014 to December 2019. Survival times were evaluated until April 2020. For the 94 patients, the underlying causes of their diseases remained unclear at the end of the follow-up period, and the 1-, 3-, and 6-month survival rates, and the overall survival (OS) rates were 86.2%, 78.7%, 73.4%, and 70.2%,… More >

  • Open Access

    REVIEW

    COVID-19: Review on Its Etiology, Pathogenesis, and Existence in Humans

    VIVEK KUMAR, VISHNU AGARWAL*

    BIOCELL, Vol.44, No.4, pp. 461-467, 2020, DOI:10.32604/biocell.2020.011090 - 24 December 2020

    Abstract The world is facing a new healthcare crisis with the rise and spread of novel coronavirus since December 2019. Also known as Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2), the disease associated with SARSCoV-2 is even called COVID-19. The infection is said to have originated from the bat community and transmitted to humans through an intermediate host (yet unknown) in Wuhan, in the Hubei region of China. COVID-19 is having a pulverizing impact on the scientific community. As of August 13, 2020, the number of confirmed cases had reached up to 20,439,814 and the death More >

  • Open Access

    ARTICLE

    Comparison of nocturia etiology in black and white male patients

    Matthew R. Epstein, Thomas F. Monaghan, Johnathan A. Khusid, Nicholas R. Suss, Christina W. Agudelo, Kyle P. Michelson, Zhan D. Wu, Fred Gong, Jeffrey P. Weiss

    Canadian Journal of Urology, Vol.26, No.3, pp. 9769-9773, 2019

    Abstract Introduction: Much of what is known about the etiology of nocturia (i.e., nocturnal polyuria [NP], small bladder capacity [SBC], etc.) at the population level stems from the Krimpen study, which enrolled aging males from a homogenous municipality in the Netherlands. Given the higher prevalence of benign prostatic hyperplasia and overactive bladder in black versus white males in population research, we aim to test the hypothesis that black males seeking treatment for lower urinary tract symptoms (LUTS) are more likely to have nocturia owing to SBC.
    Materials and methods: We retrospectively analyzed 24-hour frequency-volume charts (FVCs) completed by… More >

  • Open Access

    RESIDENT’S CORNER

    Ectopic ACTH-secreting neuroendocrine tumor: a rare etiology of a pediatric solid renal mass

    Neil J. Kocher1, Justin Loloi2, Joshua Warrick3, Amy S. Burns1, Ross M. Decter1

    Canadian Journal of Urology, Vol.26, No.5, pp. 9956-9959, 2019

    Abstract Neuroendocrine tumors (NETs) are rare tumors with varying clinical presentations. We describe the case of an 11-year-old female presenting with Cushingoid features in the setting of a left-sided flank mass. Her presentation and evaluation suggested a paraneoplastic ectopic ACTH syndrome. She underwent open left radical nephrectomy and final pathology confirming a high-grade NET with nodal metastasis. Although exceedingly rare, ACTH-secreting tumors of the kidney can cause significant morbidity and mortality and so we recommend it be included in the differential diagnosis of pediatric renal masses. More >

  • Open Access

    ARTICLE

    The role of host immune cells and Borrelia burgdorferi antigens in the etiology of Lyme disease

    Dennis Verhaegh, Leo A. B. Joosten, Marije Oosting

    European Cytokine Network, Vol.28, No.2, pp. 70-84, 2017, DOI:10.1684/ecn.2017.0396

    Abstract Lyme disease is a zoonosis caused by infection with bacteria belonging to the Borrelia burgdorferi species after the bite of an infected tick. Even though an infection by this bacterium can be effectively treated with antibiotics, when the infection stays unnoticed B. burgdorferi can persist and chronic post-treatment Lyme disease syndrome is able to develop. Although a cellular and humoral response is observed after an infection with theBorrelia bacteria, these pathogens are still capable to stay alive. Several immune evasive mechanisms have been revealed and explained and much work has been put into the understanding of the… More >

  • Open Access

    ARTICLE

    Hematuria: etiology and evaluation for the primary care physician

    Jitesh V. Patel1, Christopher V. Chambers2, Leonard G. Gomella1

    Canadian Journal of Urology, Vol.15, Suppl.4, pp. 54-62, 2008

    Abstract Asymptomatic microscopic and gross hematuria are common problems for the primary care physician. The exact defi nition of microscopic hematuria is debated, but is defi ned by one group as > 3 red blood cells/high power microscopic fi eld. While the causes of hematuria are extensive, the most common differential diagnosis for both microscopic and gross hematuria in adults includes infection, malignancy, and urolithiasis. Clinical evaluation of these patients often involves urological consultation with urine cytology, urine culture, imaging studies, and cystoscopy. Patients who have no identifi able cause after an extensive workup should be More >

  • Open Access

    RESIDENT’S CORNER

    Splenic rupture following shock wave lithotripsy

    Wesley M. White, Steven A. Morris, Frederick A. Klein, W. Bedford Waters

    Canadian Journal of Urology, Vol.15, No.4, pp. 4196-4199, 2008

    Abstract We present the case of a 61-year-old female who underwent extracorporeal shock wave lithotripsy (ESWL) treatment of a 12 mm left ureteropelvic junction stone. Following an uneventful and successful treatment, the patient was discharged. The patient re-presented to the emergency room 24 hours later with abdominal pain and hypotension. CT of the abdomen revealed a shattered spleen necessitating emergent removal. The patient recovered without difficulty. Although splenic rupture following shock wave lithotripsy (SWL) has been reported previously, this case represents the only published report of splenic rupture with use of a third generation electromagnetic lithotripter. More >

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