Menwa Alshammeri^1,2,*, Noshina Tariq³, NZ Jhanji^4,5, Mamoona Humayun⁶, Muhammad Attique Khan⁷

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074627 - 29 January 2026

Abstract Artificial Intelligence (AI) is changing healthcare by helping with diagnosis. However, for doctors to trust AI tools, they need to be both accurate and easy to understand. In this study, we created a new machine learning system for the early detection of Autism Spectrum Disorder (ASD) in children. Our main goal was to build a model that is not only good at predicting ASD but also clear in its reasoning. For this, we combined several different models, including Random Forest, XGBoost, and Neural Networks, into a single, more powerful framework. We used two different types More >

Vaskar Chakma^1,#, Xiaolin Ju^1,#, Heling Cao², Xue Feng³, Xiaodong Ji³, Haiyan Pan^3,*, Gao Zhan^1,*

Journal of Intelligent Medicine and Healthcare, Vol.4, pp. 37-86, 2026, DOI:10.32604/jimh.2026.075201 - 23 January 2026

Abstract Wide QRS Complex Tachycardia (WCT) is a life-threatening cardiac arrhythmia requiring rapid and accurate diagnosis. Traditional manual ECG interpretation is time-consuming and subject to inter-observer variability, while existing AI models often lack the clinical interpretability necessary for trusted deployment in emergency settings. We developed CardioForest, an optimized Random Forest ensemble model, for automated WCT detection from 12-lead ECG signals. The model was trained, tested, and validated using 10-fold cross-validation on 800,000 ten-second-long 12-lead Electrocardiogram (ECG) recordings from the MIMIC-IV dataset (15.46% WCT prevalence), with comparative evaluation against XGBoost, LightGBM, and Gradient Boosting models. Performance was… More >

Kirubavathi Ganapathiyappan^1,*, Kiruba Marimuthu Eswaramoorthy¹, Abi Thangamuthu Shanthamani¹, Aksaya Venugopal¹, Asita Pon Bhavya Iyyappan¹, Thilaga Manickam¹, Ateeq Ur Rehman^2,*, Habib Hamam^3,4,5,6

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-31, 2026, DOI:10.32604/cmc.2025.070067 - 09 December 2025

Abstract The growing use of Portable Document Format (PDF) files across various sectors such as education, government, and business has inadvertently turned them into a major target for cyberattacks. Cybercriminals take advantage of the inherent flexibility and layered structure of PDFs to inject malicious content, often employing advanced obfuscation techniques to evade detection by traditional signature-based security systems. These conventional methods are no longer adequate, especially against sophisticated threats like zero-day exploits and polymorphic malware. In response to these challenges, this study introduces a machine learning-based detection framework specifically designed to combat such threats. Central to… More >

Abeer Alhuzali^1,*, Qamar Al-Qahtani¹, Asmaa Niyazi¹, Lama Alshehri¹, Fatemah Alharbi²

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-19, 2026, DOI:10.32604/cmc.2025.069491 - 10 November 2025

Abstract The surge in smishing attacks underscores the urgent need for robust, real-time detection systems powered by advanced deep learning models. This paper introduces PhishNet, a novel ensemble learning framework that integrates transformer-based models (RoBERTa) and large language models (LLMs) (GPT-OSS 120B, LLaMA3.3 70B, and Qwen3 32B) to enhance smishing detection performance significantly. To mitigate class imbalance, we apply synthetic data augmentation using T5 and leverage various text preprocessing techniques. Our system employs a dual-layer voting mechanism: weighted majority voting among LLMs and a final ensemble vote to classify messages as ham, spam, or smishing. Experimental More >

Ugur Madran, Saeed Mian Qaisar^*, Duygu Soyoglu

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1969-1992, 2025, DOI:10.32604/cmes.2025.072024 - 26 November 2025

Abstract Recent advancements in smart-meter technology are transforming traditional power systems into intelligent smart grids. It offers substantial benefits across social, environmental, and economic dimensions. To effectively realize these advantages, a fine-grained collection and analysis of smart meter data is essential. However, the high dimensionality and volume of such time-series present significant challenges, including increased computational load, data transmission overhead, latency, and complexity in real-time analysis. This study proposes a novel, computationally efficient framework for feature extraction and selection tailored to smart meter time-series data. The approach begins with an extensive offline analysis, where features are… More >

Yazeed Alkhrijah¹, Marwa Fahim², Syed Muhammad Usman³, Qasim Mehmood³, Shehzad Khalid^4,5,*, Mohamad A. Alawad¹, Haya Aldossary⁶

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2339-2355, 2025, DOI:10.32604/cmes.2025.071512 - 26 November 2025

Abstract Atrial Fibrillation (AF) is a cardiac disorder characterized by irregular heart rhythms, typically diagnosed using Electrocardiogram (ECG) signals. In remote regions with limited healthcare personnel, automated AF detection is extremely important. Although recent studies have explored various machine learning and deep learning approaches, challenges such as signal noise and subtle variations between AF and other cardiac rhythms continue to hinder accurate classification. In this study, we propose a novel framework that integrates robust preprocessing, comprehensive feature extraction, and an ensemble classification strategy. In the first step, ECG signals are divided into equal-sized segments using a… More >

Alex Segura^*, Joaquim Meléndez

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 649-672, 2025, DOI:10.32604/cmes.2025.070954 - 30 October 2025

Abstract The increasing use of renewable energy sources, combined with the increase in electricity demand, has highlighted the importance of energy flexibility management in electrical grids. Energy flexibility is the capacity that generators and consumers have to change production and/or consumption to support grid operation, ensuring the stability and efficiency of the grid. Thus, Local Flexibility Markets (LFMs) are market-oriented mechanisms operated at different time horizons that support flexibility provision and trading at the distribution level, where the Distribution System Operators (DSOs) are the flexibility-demanding actors, and prosumers are the flexibility providers. This paper investigates the… More >

Mujeebu Rehman¹, Qinghua Liu¹, Ali Ghulam², Tariq Ahmad³, Jawad Khan^4,*, Dildar Hussain^5,*, Yeong Hyeon Gu⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 779-805, 2025, DOI:10.32604/cmes.2025.067412 - 30 October 2025

Abstract Identifying druggable proteins, which are capable of binding therapeutic compounds, remains a critical and resource-intensive challenge in drug discovery. To address this, we propose CEL-IDP (Comparison of Ensemble Learning Methods for Identification of Druggable Proteins), a computational framework combining three feature extraction methods Dipeptide Deviation from Expected Mean (DDE), Enhanced Amino Acid Composition (EAAC), and Enhanced Grouped Amino Acid Composition (EGAAC) with ensemble learning strategies (Bagging, Boosting, Stacking) to classify druggable proteins from sequence data. DDE captures dipeptide frequency deviations, EAAC encodes positional amino acid information, and EGAAC groups residues by physicochemical properties to generate… More >

Areeba Masood Siddiqui^1,2,*, Hyder Abbas^3,4, Muhammad Asim^5,6,*, Abdelhamied A. Ateya⁵, Hanaa A. Abdallah⁷

CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 3135-3168, 2025, DOI:10.32604/cmes.2025.069926 - 30 September 2025

Abstract Timely and accurate diagnosis of skin diseases is crucial as conventional methods are time-consuming and prone to errors. Traditional trial-and-error approaches often aggregate multiple models without optimization by resulting in suboptimal performance. To address these challenges, we propose a novel Squid Game Optimization-Dimension Reduction-based Ensemble (SGO-DRE) method for the precise diagnosis of skin diseases. Our approach begins by selecting pre-trained models named MobileNetV1, DenseNet201, and Xception for robust feature extraction. These models are enhanced with dimension reduction blocks to improve efficiency. To tackle the aggregation problem of various models, we leverage the Squid Game Optimization… More >

Naif Almusallam^1,*, Junaid Qayyum^2,3

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3653-3687, 2025, DOI:10.32604/cmc.2025.067220 - 23 September 2025

Abstract This paper proposes a novel hybrid fraud detection framework that integrates multi-stage feature selection, unsupervised clustering, and ensemble learning to improve classification performance in financial transaction monitoring systems. The framework is structured into three core layers: (1) feature selection using Recursive Feature Elimination (RFE), Principal Component Analysis (PCA), and Mutual Information (MI) to reduce dimensionality and enhance input relevance; (2) anomaly detection through unsupervised clustering using K-Means, Density-Based Spatial Clustering (DBSCAN), and Hierarchical Clustering to flag suspicious patterns in unlabeled data; and (3) final classification using a voting-based hybrid ensemble of Support Vector Machine (SVM),… More >