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  • Open Access

    ARTICLE

    CAPGen: An MLLM-Based Framework Integrated with Iterative Optimization Mechanism for Cultural Artifacts Poster Generation

    Qianqian Hu, Chuhan Li, Mohan Zhang, Fang Liu*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-17, 2026, DOI:10.32604/cmc.2025.068225 - 10 November 2025

    Abstract Due to the digital transformation tendency among cultural institutions and the substantial influence of the social media platform, the demands of visual communication keep increasing for promoting traditional cultural artifacts online. As an effective medium, posters serve to attract public attention and facilitate broader engagement with cultural artifacts. However, existing poster generation methods mainly rely on fixed templates and manual design, which limits their scalability and adaptability to the diverse visual and semantic features of the artifacts. Therefore, we propose CAPGen, an automated aesthetic Cultural Artifacts Poster Generation framework built on a Multimodal Large Language More >

  • Open Access

    REVIEW

    Revolutionizing Metabolic Engineering in Cannabis sativa L.: Harnessing the Power of Hairy Root Culture

    Md. Injamum-Ul-Hoque1,2, Md. Mahfuzur Rahman2, Nayan Chandra Howlader3, Soosan Tavakoli4, Md. Mezanur Rahman5, Shahin Imran6, Mallesham Bulle7, S. M. Ahsan2,4,*, Hyong Woo Choi4,8,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3805-3826, 2025, DOI:10.32604/phyton.2025.069827 - 29 December 2025

    Abstract Cannabis sativa is highly valued for its use in fiber production, medicine, and recreational products. Its secondary metabolites (SM) are renowned for their wide range of health benefits and psychoactive properties. While much of the existing research has focused on cannabinoid production in the plant’s aerial parts, particularly the leaves and flowers, the root system remains understudied in terms of its SM profile. One promising in vitro approach for metabolite production involves the use of ‘hairy roots (HRs)’. These roots mimic the phytochemical profile of native roots but grow more efficiently and yield higher quantities of metabolites.… More >

  • Open Access

    ARTICLE

    Engineering Amorphous Solid Dispersions of Abiraterone Acetate via HPMC HME: A Polymer-Centric Hot-Melt Extrusion Strategy for Formulation-Driven Bioavailability Improvement

    Manisha Choudhari1, Shantanu Damle2, Rajat Vashist1, Ranendra Narayan Saha3, Sunil Kumar Dubey4, Gautam Singhvi1,*

    Journal of Polymer Materials, Vol.42, No.4, pp. 1199-1229, 2025, DOI:10.32604/jpm.2025.072987 - 26 December 2025

    Abstract Abiraterone acetate (ABTA) was approved by the USFDA in 2011 for treating metastatic castration-resistant prostate cancer (mCRPC). ABTA exhibits poor aqueous solubility, inadequate dissolution, low oral bioavailability (<10%), and significant positive food effects. To overcome these limitations, in the present work, ABTA solid dispersions (SDs) were developed by using hot melt extrusion technology (HME) with various grades of hydroxypropyl methylcellulose HME (HPMC HME 15LV and 100LV) at different extrusion temperatures. HPMC HME demonstrated the ability to prevent drug precipitation for up to 120 min compared to the free drug (10 min), sustaining the supersaturation state… More > Graphic Abstract

    Engineering Amorphous Solid Dispersions of Abiraterone Acetate via HPMC HME: A Polymer-Centric Hot-Melt Extrusion Strategy for Formulation-Driven Bioavailability Improvement

  • Open Access

    ARTICLE

    Tailoring thermoelectric properties of copper selenide through engineering nano/micro-sized particles

    S. W. Jo, I. H. Kim, Y. J. Jeong*

    Chalcogenide Letters, Vol.22, No.3, pp. 189-196, 2025, DOI:10.15251/CL.2025.223.189

    Abstract Copper selenide has emerged as a promising thermoelectric material due to its unique structural properties and tunable electronic band structure. However, its practical application is hindered by its relatively high thermal conductivity. In this study, we report on the turning of thermal conductivity and thermoelectric energy conversion by preparing a hybrid composite material including nano- and micro-sized Cu₂Se. By employing a hydrothermal synthesis method with cetyltrimethylammonium bromide (CTAB) as a surfactant, we successfully synthesized nano-sized CuSe particles with uniform size distribution. The incorporation of these nano-sized particles with micro-sized Cu₂Se resulted in a significant reduction in More >

  • Open Access

    ARTICLE

    Design and synthesis of diketopyrrolopyrrole-CdS hybrid nanostructures for enhanced photovoltaic applications

    Q. Fei1,*, B. Jin2, B. C. Jiang3, J. S. Huang4, L. Li5

    Chalcogenide Letters, Vol.22, No.8, pp. 693-705, 2025, DOI:10.15251/CL.2025.228.693

    Abstract An innovative hybrid nanostructure composed of diketopyrrolopyrrole (DPP) oligomers and cadmium sulfide (CdS) nanoparticles was developed to enhance the efficiency of organic– inorganic photovoltaic devices. The DPP-CdS hybrids were synthesized via a solution-phase mixing method, resulting in uniform nanoparticle dispersion along polymer fibrils and strong interfacial coupling. Structural characterization confirmed the coexistence of crystalline CdS domains and partially ordered DPP phases, while spectroscopic analyses indicated notable redshifts and band broadening, evidencing electronic interactions at the interface. The hybrid material displayed significantly broadened light absorption across the 400–700 nm range and an optimized optical bandgap of… More >

  • Open Access

    ARTICLE

    Solid Model Generation and Shape Analysis of Human Crystalline Lens Using 3D Digitization and Scanning Techniques

    José Velázquez, Dolores Ojados, Adrián Semitiel, Francisco Cavas*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1821-1837, 2025, DOI:10.32604/cmes.2025.071131 - 26 November 2025

    Abstract This research establishes a methodological framework for generating geometrically accurate 3D representations of human crystalline lenses through scanning technologies and digital reconstruction. Multiple scanning systems were evaluated to identify optimal approaches for point cloud processing and subsequent development of parameterized solid models, facilitating comprehensive morpho-geometric characterization. Experimental work was performed at the 3D Scanning Laboratory of SEDIC (Industrial Design and Scientific Calculation Service) at the Technical University of Cartagena, employing five distinct scanner types based on structured light, laser, and infrared technologies. Test specimens—including preliminary calibration using a lentil and biological analysis of a human… More >

  • Open Access

    PROCEEDINGS

    AI-Assisted Generative Inverse Design of Heterogeneous Meta-Biomaterials Based on TPMS for Biomimetic Tissue Engineering

    Xiaolong Zhu, Feng Chen, Yuntian Chen, Wei Zhu, Xiaoxiao Han*

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.3, pp. 1-1, 2025, DOI:10.32604/icces.2025.012584

    Abstract Human tissues and organs exhibit not only intricate anatomical architectures but also spatially heterogeneous distributions of elastic modulus—for example, between cancellous and cortical bone, across the epidermis, dermis, and subcutaneous layers, and between healthy and fibrotic liver tissues. Conventional biomaterials often fail to replicate such mechanical heterogeneity, thereby limiting their capacity to recreate biomimetic physiological microenvironments essential for applications like tissue regeneration and disease modeling. Meta-biomaterials, artificially engineered through the rational structural design of continuous materials, have emerged as a promising class of materials owing to their highly tunable mechanical and biological properties. These attributes… More >

  • Open Access

    ARTICLE

    Integrated Sharing Platform for Genetic Data of Rare and Precious Metal Materials

    Lin Huang1,2, Ying Zhou2, Jingjing Yang1,*

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4587-4606, 2025, DOI:10.32604/cmc.2025.068370 - 23 October 2025

    Abstract The construction of centralized and standardized material databases is essential to support both scientific innovation and industrial application. However, for rare and precious metal materials, existing data resources are often decentralized. This results in persistent issues such as data silos and fragmentation, which significantly hinder efficient data utilization and collaboration. In response to these challenges, this study investigates the development of an integrated platform for sharing genetic data of rare and precious metal materials. The research begins by analyzing current trends in material data platforms, both domestically and internationally. These insights help inform the architectural… More >

  • Open Access

    REVIEW

    A Review of PEO (Polyethylene Oxide) Assisted Electrospinning of Chitosan: Innovation, Production, and Application

    Md. Tanvir Raihan1, Md. Himel Mahmud2, Badhon Chandra Mazumder2, Md. Nazif Hasan Chowdhury3, Mohammad Tajul Islam1,*

    Journal of Polymer Materials, Vol.42, No.3, pp. 677-711, 2025, DOI:10.32604/jpm.2025.068356 - 30 September 2025

    Abstract Electrospinning has gained significant importance across various fields, including biomedicine, filtration, and packaging due to the control it provides over the properties of the resulting materials, such as fiber diameter and membrane thickness. Chitosan is a biopolymer that can be utilized with both natural and synthetic copolymers, owing to its therapeutic potential, biocompatibility, and biodegradability. However, producing electrospun chitosan is challenging due to its high solution viscosity, which often results in the formation of beads instead of uniform fibers. To address this issue, the spinnability of chitosan is significantly enhanced, and the production of continuous More >

  • Open Access

    ARTICLE

    Type-I Heavy-Tailed Burr XII Distribution with Applications to Quality Control, Skewed Reliability Engineering Systems and Lifetime Data

    Okechukwu J. Obulezi1,*, Hatem E. Semary2, Sadia Nadir3, Chinyere P. Igbokwe4, Gabriel O. Orji1, A. S. Al-Moisheer2, Mohammed Elgarhy5

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.3, pp. 2991-3027, 2025, DOI:10.32604/cmes.2025.069553 - 30 September 2025

    Abstract This study introduces the type-I heavy-tailed Burr XII (TIHTBXII) distribution, a highly flexible and robust statistical model designed to address the limitations of conventional distributions in analyzing data characterized by skewness, heavy tails, and diverse hazard behaviors. We meticulously develop the TIHTBXII’s mathematical foundations, including its probability density function (PDF), cumulative distribution function (CDF), and essential statistical properties, crucial for theoretical understanding and practical application. A comprehensive Monte Carlo simulation evaluates four parameter estimation methods: maximum likelihood (MLE), maximum product spacing (MPS), least squares (LS), and weighted least squares (WLS). The simulation results consistently show… More >

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