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    ARTICLE

    Effects of rotational culture on morphology, nitric oxide production and cell cycle of endothelial cells

    CHAOJUN TANG1, XUE WU1, LINQI YE1,2, XIANG XIE1, GUIXUE WANG1*

    BIOCELL, Vol.36, No.3, pp. 97-104, 2012, DOI:10.32604/biocell.2012.36.097

    Abstract Devices for the rotational culture of cells and the study of biological reactions have been widely applied in tissue engineering. However, there are few reports exploring the effects of rotational culture on cell morphology, nitric oxide (NO) production, and cell cycle of the endothelial cells from human umbilical vein on the stent surface. This study focuses on these parameters after the cells are seeded on the stents. Results showed that covering of stents by endothelial cells was improved by rotational culture. NO production decreased within 24 h in both rotational and static culture groups. In More >

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