RAQUEL GÓMEZ-MOLINA^1,*, RAQUEL MARTÍNEZ^2,3,4, MIGUEL SUÁREZ^2,3,4,*, ANA PEÑA-CABIA¹, MARíA CONCEPCIóN CALDERÓN¹, JORGE MATEO^3,4

Oncology Research, Vol.33, No.7, pp. 1531-1545, 2025, DOI:10.32604/or.2025.063951 - 26 June 2025

Abstract Lynch syndrome (LS), also known as hereditary non-polyposis colorectal cancer (HNPCC), is an inherited condition associated with a higher risk of colorectal cancer (CRC) and other cancers. It is caused by germline mutations in DNA mismatch repair (MMR) genes, including MLH1, MSH2, MSH6 and PMS2. These mutations lead to microsatellite instability (MSI) and defective DNA repair mechanisms, resulting in increased cancer risk. Early detection of LS is crucial for effective management and cancer prevention. Endoscopic surveillance, particularly regular colonoscopy, is recommended for individuals with LS to detect CRC at early stages. Additionally, universal screening of CRC for More > Graphic Abstract

Shiren Ye, Qi Meng, Shuo Zhang, Hui Wang^*

CMC-Computers, Materials & Continua, Vol.82, No.2, pp. 2415-2429, 2025, DOI:10.32604/cmc.2024.058250 - 17 February 2025

Abstract WCE (Wireless Capsule Endoscopy) is a new technology that combines computer vision and medicine, allowing doctors to visualize the conditions inside the intestines, achieving good diagnostic results. However, due to the complex intestinal environment and limited pixel resolution of WCE videos, lesions are not easily detectable, and it takes an experienced doctor 1–2 h to analyze a complete WCE video. The use of computer-aided diagnostic methods, assisting or even replacing manual WCE diagnosis, has significant application value. In response to the issue of intestinal lesion detection in WCE videos, this paper proposes a multi-scale feature… More >

Mousa Alhajlah¹, Muhammad Nouman Noor², Muhammad Nazir², Awais Mahmood^1,*, Imran Ashraf³, Tehmina Karamat⁴

CMC-Computers, Materials & Continua, Vol.75, No.1, pp. 2227-2245, 2023, DOI:10.32604/cmc.2023.031890 - 06 February 2023

Abstract Gastrointestinal diseases like ulcers, polyps’, and bleeding are increasing rapidly in the world over the last decade. On average 0.7 million cases are reported worldwide every year. The main cause of gastrointestinal diseases is a Helicobacter Pylori (H. Pylori) bacterium that presents in more than 50% of people around the globe. Many researchers have proposed different methods for gastrointestinal disease using computer vision techniques. Few of them focused on the detection process and the rest of them performed classification. The major challenges that they faced are the similarity of infected and healthy regions that misleads the… More >

Muhammad Arslan Usman¹, Muhammad Rehan Usman², Gandeva Bayu Satrya³, Muhammad Ashfaq Khan⁴, Christos Politis¹, Nada Philip¹, Soo Young Shin^5,*

CMC-Computers, Materials & Continua, Vol.67, No.2, pp. 1697-1712, 2021, DOI:10.32604/cmc.2021.014696 - 05 February 2021

Abstract With the advent in services such as telemedicine and telesurgery, provision of continuous quality monitoring for these services has become a challenge for the network operators. Quality standards for provision of such services are application specific as medical imagery is quite different than general purpose images and videos. This paper presents a novel full reference objective video quality metric that focuses on estimating the quality of wireless capsule endoscopy (WCE) videos containing bleeding regions. Bleeding regions in gastrointestinal tract have been focused in this research, as bleeding is one of the major reasons behind several… More >

Jonathan Ewald¹, Herbert Hodgson¹, Jerry Thomas¹, Nazih Khater², Mohamed Keheila², Muhannad Alsyouf², Javier L. Arenas², Mohammad Hajiha², D. Duane Baldwin²

Canadian Journal of Urology, Vol.27, No.2, pp. 10174-10180, 2020

Abstract Introduction: To improve the success rate and safety of ureteral stent insertion, we sought to identify the effect of guidewire type and prior use upon the force needed to advance a 6Fr ureteral stent over various guidewires.
Materials and methods: Two hundred forty stent insertion trials were performed in an ex vivo porcine urinary tract model. Ten trials were randomly performed over 12 new and 12 used guidewires. For each trial, the force required to advance a 6Fr Cook double-pigtail ureteral stent was recorded. Guidewires included the Olympus Glidewire, Cook Fixed Core, and Boston Scientific Amplatz Super… More >

Jim K. Shen, Edmund Y. Ko, Andrea Staack

Canadian Journal of Urology, Vol.23, No.5, pp. 8487-8490, 2016

Abstract A 42-year-old female with remote history of intrauterine device (IUD) placement presented with gross hematuria, urinary urgency, and dyspareunia. Cystoscopy showed an encrusted, free-floating intravesical foreign body consistent with a heavily calcified IUD. It was removed endoscopically using holmium laser cystolitholapaxy. The patient remained symptom free postoperatively. While most intravesical IUDs are thought to be the result of migration after several months, this patient became pregnant within 4 weeks after initial insertion. Therefore this may represent a case either of early intravesical migration or of accidental IUD placement into the bladder at the time of More >

Aditya Bagrodia, Deniz Gerecci, Daniel Ramirez, Daniel B. Decker, Steven J. Hudak

Canadian Journal of Urology, Vol.19, No.5, pp. 6477-6479, 2012

Abstract Prostatic utricle (PU) stones are rare and the surgical treatment of such PU anomalies has proved challenging given their location adjacent to the posterior urethra and proximity to important fertility and continence structures. We report the case of a 58-year-old male with hypospadias, microphallus, and irritative lower urinary tract symptoms (LUTS) found to have a large PU stone. He underwent successful complete endoscopic removal of the stone via transurethral unroofing and holmium laser litholapaxy. We conclude that it is an effective alternative to other surgical techniques once size of the stone and the patient’s individual More >

Michael Mastromichalis, Daniel Sackman, James F. Tycast, Micheal J. Chehval

Canadian Journal of Urology, Vol.18, No.5, pp. 5916-5917, 2011

Abstract Not uncommonly, hostile prison environments can lead desperate prisoners to place foreign materials into natural orifi ces in an effort to gain transfer to an outside healthcare facility. In this article, we present a case series of urethral foreign body insertion of varying burdens and durations requiring transfer to our facility for surgical management. Endoscopic retrieval was the initial management in each case; one case required conversion to open cystotomy for complete removal due the orientation, amount of inserted foreign body, and erosion into the proximal urethral and bladder urothelium. More >

Jonah S. Marshall, Allison L. Cardin, Ganesh Palapattu

Canadian Journal of Urology, Vol.15, No.1, pp. 3936-3938, 2008

Abstract Patients present with foreign bodies in the genitourinary tract of a surprising array of shapes and sizes. We present a case of a woman with a metallic pipe lodged in the bladder and a novel technique for removing it. The patient underwent cystoscopy and a prolene snare was fashioned intraoperatively which facilitated safe and rapid extraction of the metallic pipe. Foreign bodies in the genitourinary tract present the urologist with a unique challenge and we present a simple, cheap, and effective way of managing these objects using an easily constructed cystoscopic snare. More >