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  • Open Access

    ARTICLE

    Donor-gifted nephrolithiasis: case-based analysis and comparative study

    Maxwell Sandberg1,*, Mark Xu1, Randall Bissette1, Jacob Malakismail2, Niara East3, Robenson Nguyen4, Jackson Nowatzke1, Robert Stratta5, Dean Assimos1,6, Colin Kleinguetl1

    Canadian Journal of Urology, Vol.32, No.6, pp. 633-641, 2025, DOI:10.32604/cju.2025.069091 - 30 December 2025

    Abstract Objectives: Donor-gifted nephrolithiasis—the presence of a stone in a donor kidney at the time of transplantation—is rare. Research is limited, and no consensus high-quality evidence guidelines exist, leaving selection criteria and management to individual provider discretion. We aimed to estimate the frequency and analyze patient and graft outcomes of deceased donor (DD) transplant recipients with stones in their kidneys at Wake Forest Baptist Medical Center. Methods: All DD renal transplants or patients receiving most of their care postoperatively after DD renal transplantation at our institution from 1979 to 2025 were reviewed. Stones were considered donor-gifted… More >

  • Open Access

    ARTICLE

    Preoperative ECMO Bridging in Pediatric Heart Transplantation: A Cohort Study on Graft Remodeling, Inflammatory Biomarkers and Survival

    Hui Yi1,2,#, Hongjian Shi2,3,#, Fuquan Kan2,4,#, Fan Han2, Lei Wan5, Xiaoyang Hong1, Zhe Zhao1, Junjie Shao2, Gang Wang1, Hui Wang1, Hua Yan5, Xiujuan Shi1, Ran Zhang2,6,*, Gengxu Zhou1,*

    Congenital Heart Disease, Vol.20, No.4, pp. 519-530, 2025, DOI:10.32604/chd.2025.067164 - 18 September 2025

    Abstract Background: To investigate the impact of preoperative extracorporeal membrane oxygenation (ECMO) on clinical outcomes in pediatric heart transplantation (PHT). Methods: This retrospective cohort analysis was conducted on 19 pediatric heart transplant recipients, divided into two groups: ECMO and non-ECMO, based on whether preoperative ECMO was utilized. We evaluated the patients’ surgical conditions, postoperative complications, and survival rates. Additionally, the analysis focused on the differences and correlations in clinical characteristics, inflammatory markers, and long-term survival outcomes. Results: There was no statistically significant difference in perioperative survival rates between the ECMO group (85.7%) and the non-ECMO group (83.3%). However,… More >

  • Open Access

    ARTICLE

    DFT and TD-DFT Calculations of Orbital Energies and Photovoltaic Properties of Small Molecule Donor and Acceptor Materials Used in Organic Solar Cells

    Daniel Dodzi Yao Setsoafia1, Kiran Sreedhar Ram1, Hooman Mehdizadeh-Rad1,2, David Ompong1,2, Vinuthaa Murthy1,2, Jai Singh1,2,*

    Journal of Renewable Materials, Vol.10, No.10, pp. 2553-2567, 2022, DOI:10.32604/jrm.2022.020967 - 08 June 2022

    Abstract DFT and TD-DFT calculations of HOMO and LUMO energies and photovoltaic properties are carried out on four selected pentathiophene donor and one IDIC-4F acceptor molecules using B3LYP and PBE0 functionals for the ground state energy calculations and CAM-B3LYP functional for the excited state calculations. The discrepancy between the calculated and experimental energies is reduced by correlating them with a linear fit. The fitted energies of HOMO and LUMO are used to calculate the Voc of an OSC based on these donors and acceptor blend and compared with experimental values. Using the Scharber model the calculated PCE… More >

  • Open Access

    ARTICLE

    Ischemic time of graft liver forces Th1-to-Th2 activity toward Th1 activity in patients who underwent living donor liver transplantation

    Chul Soo Park1, Hye Young Moon2, Sangbin Han2, Jin Young Chon2, Min Suk Chae1, Sang Hyun Hong1, Jong Ho Choi1, Hyun Sik Chung1

    European Cytokine Network, Vol.30, No.1, pp. 23-28, 2019, DOI:10.1684/ecn.2019.0422

    Abstract Recipient’s immune responses are an important factor in allograft survival in transplantation. Cytokines are reflected with immune responses. In the present study, we aimed to evaluate potential affecting factors of liver allograft survival and their possible correlation with seroum cytokine levels in living donor liver transplantation (LDLT). One hundred and seventy-one adult patients’ data were collected retrospectively. Five cytokines were collected: interferon (IFN)-γ, interleukin (IL)-2, IL-10, IL-6, and IL-17. Ischemic time of liver grafts was divided into two periods: cold and warm ischemic times (CIT and WIT, respectively). CIT had no statically significant correlation, but… More >

  • Open Access

    RESIDENT’S CORNER

    Ex-vivo donor partial nephrectomy at the time of donor-directed renal transplantation

    Eric C. Wendel, Raunak D. Patel, Daniel J. Canter

    Canadian Journal of Urology, Vol.26, No.2, pp. 9740-9742, 2019

    Abstract The outcome of nephron-sparing surgical management of small renal masses is generally favorable, specifically in terms of long term renal function, overall survival, and oncologic outcomes. Given the overall prognosis and renal function preservation, transplantation of kidneys with small renal masses has increasingly been accepted as a donor option for renal transplantation. We present a case of an incidental renal mass on preoperative donor transplant evaluation and subsequent ex-vivo donor partial nephrectomy at the time of renal transplantation. More >

  • Open Access

    ARTICLE

    Postoperative risk of chronic kidney disease in radical nephrectomy and donor nephrectomy patients: a comparison and analysis of predictive factors

    Fiona Mei Wen Wu1, Melissa Hui Wen Tay1, Zhaojin Chen2, Bee Choo Tai3,4, Lincoln Guan Lim Tan1, Lata Raman1, Ho Yee Tiong1

    Canadian Journal of Urology, Vol.21, No.4, pp. 7351-7357, 2014

    Abstract Introduction: To compare baseline renal function and identify predictive factors in patients undergoing radical nephrectomy (RN) or donor nephrectomy (DN) and their risk of subsequent chronic kidney disease (CKD) after surgery.
    Materials and methods: A retrospective review of patients with no baseline CKD undergoing RN (n = 88) and DN (n = 58) from 2000 to 2008 was performed. Baseline and postoperative renal function (eGFR) was determined using the Modification of Diet in Renal Disease (MDRD) formula. CKD was defined as eGFR < 60 mL/min/1.73 m² according to the National Kidney Foundation guidelines.
    Results: Before surgery, patients undergoing… More >

  • Open Access

    ARTICLE

    Ureteral stricture formation in laparoscopically procured living donor kidney transplantation

    Mark D. Tyson1, Erik P. Castle1, Paul E. Andrews1, Raymond L. Heilman2, Adyr A. Moss2, David C. Mulligan2, Kunam S. Reddy2

    Canadian Journal of Urology, Vol.19, No.2, pp. 6188-6192, 2012

    Abstract Introduction: To identify the incidence of and risk factors for ureteral stricture formation in laparoscopically procured living donor kidney transplantation (LLDKT).
    Materials and methods: An IRB approved retrospective review of our institution's living donor database was performed. Patients were divided into two cohorts, those with ureteral strictures requiring procedural intervention and those without evidence of ureteral strictures. Analysis was limited to those patients with at least one year of follow up.
    Results: Of the 584 LLDKT's performed at our institution since June 1999, 510 had at least 1 year of follow up. Four hundred and ninety-six patients had… More >

  • Open Access

    ARTICLE

    Attitudes and predictive factors for live kidney donation in British Columbia. A comparison of recipients and wait-list patients

    William A. Gourlay1, Lynn Stothers2, Li Liu1,3

    Canadian Journal of Urology, Vol.12, No.1, pp. 2511-2520, 2005

    Abstract Introduction: Live donor kidney transplantation (LDKT) is both medically and economically superior to cadaver kidney transplantation in the treatment of patients with chronic renal failure. Unfortunately, fewer than 50% of patients on the transplant waiting list have a relative or friend who contacts the transplant program about possible donation. We hypothesized that both the potential recipient and potential donor have identifiable and modifiable characteristics that contribute to the likelihood of a live donor transplant.
    Materials and methods: Specifically-designed and validated questionnaires addressing personal characteristics, knowledge and beliefs about LDKT were mailed to patients who had previously received… More >

  • Open Access

    EDITORIAL

    Live donor nephrectomy

    Laurence H. Klotz

    Canadian Journal of Urology, Vol.12, No.1, pp. 2506-2506, 2005

    Abstract This article has no abstract. More >

  • Open Access

    RESIDENT’S CORNER

    Preoperative evaluation of laparoscopic living renal donors with computerized tomography and its effect on donor morbidity and graft function

    A. H. Feifer, B. C. Fong, L. Feldman, G. Fried, L. A. Stein, P. Metrakos, S. Bergman, M. Anidjar

    Canadian Journal of Urology, Vol.12, No.3, pp. 2713-2721, 2005

    Abstract Objective: To assess the efficacy of CT angiography (CTA) in evaluating the renovascular anatomy in 50 patients who underwent laparoscopic donor nephrectomy, and to correlate results with donor morbidity and recipient outcome.
    Methods: Forty-eight patients were evaluated by CTA prior to laparoscopy. Donors with aberrant renovasculature and their respective recipients were divided into: 1) accurate preoperative CTA ("predictive group", PG), 2) inaccurate CTA ("non-predictive group", NPG). Warm ischemia times (WIT), estimated blood loss (EBL), operative time (OT), and the open conversion rate were compared. Recipient creatinine values on post-operative day 1 and 3 months were recorded with… More >

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