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  • Open Access

    ARTICLE

    Nodule Detection Using Local Binary Pattern Features to Enhance Diagnostic Decisions

    Umar Rashid1,2,*, Arfan Jaffar1,2, Muhammad Rashid3, Mohammed S. Alshuhri4, Sheeraz Akram1,4,5

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3377-3390, 2024, DOI:10.32604/cmc.2024.046320

    Abstract Pulmonary nodules are small, round, or oval-shaped growths on the lungs. They can be benign (noncancerous) or malignant (cancerous). The size of a nodule can range from a few millimeters to a few centimeters in diameter. Nodules may be found during a chest X-ray or other imaging test for an unrelated health problem. In the proposed methodology pulmonary nodules can be classified into three stages. Firstly, a 2D histogram thresholding technique is used to identify volume segmentation. An ant colony optimization algorithm is used to determine the optimal threshold value. Secondly, geometrical features such as lines, arcs, extended arcs, and… More >

  • Open Access

    ARTICLE

    Privacy-Preserving Federated Deep Learning Diagnostic Method for Multi-Stage Diseases

    Jinbo Yang1, Hai Huang1, Lailai Yin2, Jiaxing Qu3, Wanjuan Xie4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.3, pp. 3085-3099, 2024, DOI:10.32604/cmes.2023.045417

    Abstract Diagnosing multi-stage diseases typically requires doctors to consider multiple data sources, including clinical symptoms, physical signs, biochemical test results, imaging findings, pathological examination data, and even genetic data. When applying machine learning modeling to predict and diagnose multi-stage diseases, several challenges need to be addressed. Firstly, the model needs to handle multimodal data, as the data used by doctors for diagnosis includes image data, natural language data, and structured data. Secondly, privacy of patients’ data needs to be protected, as these data contain the most sensitive and private information. Lastly, considering the practicality of the model, the computational requirements should… More >

  • Open Access

    REVIEW

    A Review of the Application of Artificial Intelligence in Orthopedic Diseases

    Xinlong Diao, Xiao Wang*, Junkang Qin, Qinmu Wu, Zhiqin He, Xinghong Fan

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2617-2665, 2024, DOI:10.32604/cmc.2024.047377

    Abstract In recent years, Artificial Intelligence (AI) has revolutionized people’s lives. AI has long made breakthrough progress in the field of surgery. However, the research on the application of AI in orthopedics is still in the exploratory stage. The paper first introduces the background of AI and orthopedic diseases, addresses the shortcomings of traditional methods in the detection of fractures and orthopedic diseases, draws out the advantages of deep learning and machine learning in image detection, and reviews the latest results of deep learning and machine learning applied to orthopedic image detection in recent years, describing the contributions, strengths and weaknesses,… More >

  • Open Access

    ARTICLE

    Explainable Conformer Network for Detection of COVID-19 Pneumonia from Chest CT Scan: From Concepts toward Clinical Explainability

    Mohamed Abdel-Basset1, Hossam Hawash1, Mohamed Abouhawwash2,3,*, S. S. Askar4, Alshaimaa A. Tantawy1

    CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 1171-1187, 2024, DOI:10.32604/cmc.2023.044425

    Abstract The early implementation of treatment therapies necessitates the swift and precise identification of COVID-19 pneumonia by the analysis of chest CT scans. This study aims to investigate the indispensable need for precise and interpretable diagnostic tools for improving clinical decision-making for COVID-19 diagnosis. This paper proposes a novel deep learning approach, called Conformer Network, for explainable discrimination of viral pneumonia depending on the lung Region of Infections (ROI) within a single modality radiographic CT scan. Firstly, an efficient U-shaped transformer network is integrated for lung image segmentation. Then, a robust transfer learning technique is introduced to design a robust feature… More >

  • Open Access

    ARTICLE

    Bioinformatic analysis and in vivo validation of angiogenesis related genes in inflammatory bowel disease

    ZEPENG DONG, CHENYE ZHAO, SHIBO HU, KUI YANG, JUNHUI YU*, XUEJUN SUN, JIANBAO ZHENG*

    BIOCELL, Vol.47, No.12, pp. 2735-2745, 2023, DOI:10.32604/biocell.2023.043422

    Abstract Objectives: Angiogenesis plays a significant role in the occurrence and development of inflammatory bowel disease (IBD). The aim of this study is to explore potential angiogenesis related genes (ARGs) in IBD through bioinformatics analysis and in vivo experiments. Methods: GSE57945, GSE87466, and GSE36807 were obtained from the Gene Expression Omnibus database. GSE57945 was used as the training set, while GSE87466 and GSE36807 were used as the validation set. The key ARGs associated with IBD were identified using the least absolute shrinkage and selection operator (LASSO) and random forest methods. These identified ARGs were then utilized to construct a diagnostic model… More >

  • Open Access

    ARTICLE

    Diagnostic and classification value of immune-related lncRNAs in dilated cardiomyopathy

    CONGCHEN BAI1, QIHANG KONG2, HAO TANG2, SHUWEN ZHANG2, JUNTENG ZHOU3,*, XIAOJING LIU2,4,*

    BIOCELL, Vol.47, No.11, pp. 2517-2533, 2023, DOI:10.32604/biocell.2023.043864

    Abstract Background: Various physiological mechanisms are linked to dilated cardiomyopathy (DCM) development, including oxidative stress, immune irregularities, inflammation, fibrosis, and genetic changes. However, precise molecular drivers of DCM, especially regarding abnormal immune responses, remain unclear. This study investigates immune-related long non-coding RNAs (lncRNAs) in DCM’s diagnostic and therapeutic potential. Methods: GSE141910, GSE135055, and GSE165303 datasets were acquired from the GEO database. LASSO, SVM-RFE, and random forest algorithms identified DCM-associated immune-related lncRNAs. Diagnostic capabilities were assessed by Nomogram and receiver operating characteristic (ROC) curves. Multivariate linear regression explored lncRNA correlations with ejection fraction. Single-sample gene set enrichment analysis (ssGSEA) gauged immune cell… More > Graphic Abstract

    Diagnostic and classification value of immune-related lncRNAs in dilated cardiomyopathy

  • Open Access

    ARTICLE

    A Smart Heart Disease Diagnostic System Using Deep Vanilla LSTM

    Maryam Bukhari1, Sadaf Yasmin1, Sheneela Naz2, Mehr Yahya Durrani1, Mubashir Javaid3, Jihoon Moon4, Seungmin Rho5,*

    CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 1251-1279, 2023, DOI:10.32604/cmc.2023.040329

    Abstract Effective smart healthcare frameworks contain novel and emerging solutions for remote disease diagnostics, which aid in the prevention of several diseases including heart-related abnormalities. In this context, regular monitoring of cardiac patients through smart healthcare systems based on Electrocardiogram (ECG) signals has the potential to save many lives. In existing studies, several heart disease diagnostic systems are proposed by employing different state-of-the-art methods, however, improving such methods is always an intriguing area of research. Hence, in this research, a smart healthcare system is proposed for the diagnosis of heart disease using ECG signals. The proposed framework extracts both linear and… More >

  • Open Access

    ARTICLE

    Genetic algorithm-optimized backpropagation neural network establishes a diagnostic prediction model for diabetic nephropathy: Combined machine learning and experimental validation in mice

    WEI LIANG1,2,*, ZONGWEI ZHANG1,2, KEJU YANG1,2,3, HONGTU HU1,2, QIANG LUO1,2, ANKANG YANG1,2, LI CHANG4, YUANYUAN ZENG4

    BIOCELL, Vol.47, No.6, pp. 1253-1263, 2023, DOI:10.32604/biocell.2023.027373

    Abstract Background: Diabetic nephropathy (DN) is the most common complication of type 2 diabetes mellitus and the main cause of end-stage renal disease worldwide. Diagnostic biomarkers may allow early diagnosis and treatment of DN to reduce the prevalence and delay the development of DN. Kidney biopsy is the gold standard for diagnosing DN; however, its invasive character is its primary limitation. The machine learning approach provides a non-invasive and specific criterion for diagnosing DN, although traditional machine learning algorithms need to be improved to enhance diagnostic performance. Methods: We applied high-throughput RNA sequencing to obtain the genes related to DN tubular… More >

  • Open Access

    ARTICLE

    Diagnostic qualité et apurement des données de mobilité quotidienne issues de l’enquête mixte et longitudinale Mobi’Kids

    S. Duroudier1 , S. Chardonnel1, B. Mericskay2 , I. Andre-Poyaud1 , O. Bedel3 , S. Depeau2, T. Devogele4, L. Etienne4, A. Lepetit2, C. Moreau4, N. Pelletier2 , E. Ployon1, K. Tabaka1

    Revue Internationale de Géomatique, Vol.30, No.1, pp. 127-148, 2020, DOI:10.3166/rig.2020.00105

    Abstract This paper aims at proposing a data quality diagnosis and cleansing data methodology experimented on an individual mobility survey (Mobi’Kids program). The first section presents the theoretical approach to highlight the issue of a data quality diagnosis applied to heterogeneous data collected from mixed methods (GPS tracks, surveys, observations). Secondly, two typologies of major errors are discussed according to their origin (GPS, algorithm, survey) and their nature (completeness, accuracy, consistency). A processing chain is thirdly defined to improve both internal and external data quality in order to the perspective of a replicable methodology.

    RÉSUMÉ
    Cet article a pour objectif de… More >

  • Open Access

    EDITORIAL

    Qu’en est-il des dispositifs d’accompagnement de la vie professionnelle après un diagnostic de cancer ?

    B. Porro, K. Lamore

    Psycho-Oncologie, Vol.17, No.1, pp. 1-4, 2023, DOI:10.3166/pson-2022-0229

    Abstract This article has no abstract. More >

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