Kusum Yadav¹, Yasser Alharbi¹, Eissa Jaber Alreshidi¹, Abdulrahman Alreshidi¹, Anuj Kumar Jain², Anurag Jain³, Kamal Kumar⁴, Sachin Sharma⁵, Brij B. Gupta^6,7,8,*

CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 2665-2683, 2024, DOI:10.32604/cmc.2024.053565 - 18 November 2024

Abstract In today’s world, image processing techniques play a crucial role in the prognosis and diagnosis of various diseases due to the development of several precise and accurate methods for medical images. Automated analysis of medical images is essential for doctors, as manual investigation often leads to inter-observer variability. This research aims to enhance healthcare by enabling the early detection of diabetic retinopathy through an efficient image processing framework. The proposed hybridized method combines Modified Inertia Weight Particle Swarm Optimization (MIWPSO) and Fuzzy C-Means clustering (FCM) algorithms. Traditional FCM does not incorporate spatial neighborhood features, making More >

Atta Rahman^1,*, Mustafa Youldash², Ghaida Alshammari², Abrar Sebiany², Joury Alzayat², Manar Alsayed², Mona Alqahtani², Noor Aljishi²

CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 4561-4576, 2024, DOI:10.32604/cmc.2024.055106 - 12 September 2024

Abstract Diabetes is a serious health condition that can cause several issues in human body organs such as the heart and kidney as well as a serious eye disease called diabetic retinopathy (DR). Early detection and treatment are crucial to prevent complete blindness or partial vision loss. Traditional detection methods, which involve ophthalmologists examining retinal fundus images, are subjective, expensive, and time-consuming. Therefore, this study employs artificial intelligence (AI) technology to perform faster and more accurate binary classifications and determine the presence of DR. In this regard, we employed three promising machine learning models namely, support… More >

WENBIN LUO¹, YULING ZOU², HONGXI WU³, ZHONGYI YANG¹, ZHIPENG YOU^2,*

BIOCELL, Vol.48, No.8, pp. 1275-1284, 2024, DOI:10.32604/biocell.2024.051045 - 02 August 2024

Abstract Background: Diabetes retinopathy (DR) is a complication of diabetes that affects patients’ vision. Previous studies have found blueberry anthocyanins extract (BAE) can inhibit the progression of DR, but its mechanism is not completely clear. Methods: To study the role of BAE in diabetes retinopathy, we treated human retinal endothelial cells (HRCECs) with 30 mM high glucose to simulate the microenvironment of diabetes retinopathy and used BAE to intervene the in vitro high glucose-induced retinopathy model. HRCEC cell viability and apoptosis rates were examined by Cell Counting Kit 8 (CCK-8) assay and flow cytometry assay. The binding… More >

V. Thanikachalam^1,*, M. G. Kavitha², V. Sivamurugan¹

Computer Systems Science and Engineering, Vol.48, No.3, pp. 857-858, 2024, DOI:10.32604/csse.2024.052484 - 20 May 2024

Abstract This article has no abstract. More >

Zhuoqun Xia¹, Hangyu Hu¹, Wenjing Li^2,3, Qisheng Jiang¹, Lan Pu¹, Yicong Shu¹, Arun Kumar Sangaiah^4,5,*

CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.1, pp. 409-430, 2024, DOI:10.32604/cmes.2024.030052 - 16 April 2024

Abstract Early screening of diabetes retinopathy (DR) plays an important role in preventing irreversible blindness. Existing research has failed to fully explore effective DR lesion information in fundus maps. Besides, traditional attention schemes have not considered the impact of lesion type differences on grading, resulting in unreasonable extraction of important lesion features. Therefore, this paper proposes a DR diagnosis scheme that integrates a multi-level patch attention generator (MPAG) and a lesion localization module (LLM). Firstly, MPAG is used to predict patches of different sizes and generate a weighted attention map based on the prediction score and… More >

Anas Bilal¹, Azhar Imran², Talha Imtiaz Baig^3,4, Xiaowen Liu^1,*, Haixia Long¹, Abdulkareem Alzahrani⁵, Muhammad Shafiq⁶

Computer Systems Science and Engineering, Vol.48, No.2, pp. 511-528, 2024, DOI:10.32604/csse.2023.039672 - 19 March 2024

Abstract Artificial Intelligence (AI) is being increasingly used for diagnosing Vision-Threatening Diabetic Retinopathy (VTDR), which is a leading cause of visual impairment and blindness worldwide. However, previous automated VTDR detection methods have mainly relied on manual feature extraction and classification, leading to errors. This paper proposes a novel VTDR detection and classification model that combines different models through majority voting. Our proposed methodology involves preprocessing, data augmentation, feature extraction, and classification stages. We use a hybrid convolutional neural network-singular value decomposition (CNN-SVD) model for feature extraction and selection and an improved SVM-RBF with a Decision Tree More >

Heba M. El-Hoseny^1,*, Heba F. Elsepae², Wael A. Mohamed², Ayman S. Selmy²

CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 1855-1872, 2023, DOI:10.32604/cmc.2023.042107 - 29 November 2023

Abstract Diabetic retinopathy is a critical eye condition that, if not treated, can lead to vision loss. Traditional methods of diagnosing and treating the disease are time-consuming and expensive. However, machine learning and deep transfer learning (DTL) techniques have shown promise in medical applications, including detecting, classifying, and segmenting diabetic retinopathy. These advanced techniques offer higher accuracy and performance. Computer-Aided Diagnosis (CAD) is crucial in speeding up classification and providing accurate disease diagnoses. Overall, these technological advancements hold great potential for improving the management of diabetic retinopathy. The study’s objective was to differentiate between different classes… More >

Hengyang Liu, Chuncheng Huang^*

CMC-Computers, Materials & Continua, Vol.76, No.2, pp. 1745-1761, 2023, DOI:10.32604/cmc.2023.040710 - 30 August 2023

Abstract In the field of medical images, pixel-level labels are time-consuming and expensive to acquire, while image-level labels are relatively easier to obtain. Therefore, it makes sense to learn more information (knowledge) from a small number of hard-to-get pixel-level annotated images to apply to different tasks to maximize their usefulness and save time and training costs. In this paper, using Pixel-Level Labeled Images for Multi-Task Learning (PLDMLT), we focus on grading the severity of fundus images for Diabetic Retinopathy (DR). This is because, for the segmentation task, there is a finely labeled mask, while the severity… More >

UMAPATHY PRAKASH¹, SUBRAMANIAM RAJESH BHARATHIDEVI^1,*, RAMYA R. NADIG², RAJIV RAMAN², GIRISH SHIV RAO², MUNA BHENDE²

BIOCELL, Vol.47, No.7, pp. 1473-1482, 2023, DOI:10.32604/biocell.2023.027804 - 21 June 2023

Abstract Zinc alpha 2 glycoprotein (ZAG) is a 41 KDa secretory soluble glycoprotein found in different body fluids like the serum, saliva, sweat, breast milk, and urine. It is also found in tissues like the testis, epididymis, kidney, spleen, liver, lungs, heart, and brain. ZAG is an adipokine with multiple roles, including lipid mobilization, modulating glucose metabolisms, improving insulin sensitivity, inhibiting tumor proliferation through RNAse activity, and suppressing inflammation. Low levels of zinc and ZAG are linked to metabolic syndrome and are also reported as potential biomarkers for diabetic nephropathy. Interestingly zinc has been found to More >

S. Deva Kumar, S. Venkatramaphanikumar^*, K. Venkata Krishna Kishore

Intelligent Automation & Soft Computing, Vol.37, No.1, pp. 1013-1032, 2023, DOI:10.32604/iasc.2023.038165 - 29 April 2023

Abstract Type 2 diabetes patients often suffer from microvascular complications of diabetes. These complications, in turn, often lead to vision impairment. Diabetic Retinopathy (DR) detection in its early stage can rescue people from long-term complications that could lead to permanent blindness. In this study, we propose a complex deep convolutional neural network architecture with an inception module for automated diagnosis of DR. The proposed novel Hybrid Inception U-Net (HIUNET) comprises various inception modules connected in the U-Net fashion using activation maximization and filter map to produce the image mask. First, inception blocks were used to enlarge… More >