Xiaoxue Zhou¹, Tingyang Yang², Ye Zhang¹, Yanping Ruan¹, Jiancheng Han¹, Xiaowei Liu¹, Ying Zhao¹, Xiaoyan Gu¹, Tingting Liu¹, Hairui Wang¹, Yihua He^1,*

Congenital Heart Disease, Vol.18, No.3, pp. 387-397, 2023, DOI:10.32604/chd.2023.029060

Abstract Background: Atrioventricular septal defects (AVSDs) are screened and diagnosed usually rely on the imaging characteristics of fetal echocardiography (FE). However, diagnosis on images is heavily depended on sonographers’ experience and the quantitative data are rarely studied. Objective: This study aimed to realize the prenatal diagnosis of AVSDs by analyzing the quantitative data on FE. Methods: One hundred and thirteen cardiac quantitative data was analyzed in 370 normal and 49 AVSDs fetuses retrospectively. The top six with the highest diagnostic accuracy rate were acquired according to the area under the curve (AUC), and the diagnostic value of six variables was analyzed.… More >

Yea-Sul Kim¹, Ye-Eun Kim¹, Hwankuk Kim^2,*

Computer Systems Science and Engineering, Vol.47, No.1, pp. 1125-1147, 2023, DOI:10.32604/csse.2023.039550

Abstract With the commercialization of 5th-generation mobile communications (5G) networks, a large-scale internet of things (IoT) environment is being built. Security is becoming increasingly crucial in 5G network environments due to the growing risk of various distributed denial of service (DDoS) attacks across vast IoT devices. Recently, research on automated intrusion detection using machine learning (ML) for 5G environments has been actively conducted. However, 5G traffic has insufficient data due to privacy protection problems and imbalance problems with significantly fewer attack data. If this data is used to train an ML model, it will likely suffer from generalization errors due to… More >

Bin Zhang^*

International Journal of Mental Health Promotion, Vol.25, No.5, pp. 655-671, 2023, DOI:10.32604/ijmhp.2023.025913

Abstract In the face of fierce competition in the social environment, mental health problems gradually get the attention of the public, in order to achieve accurate mental health data analysis, the construction of music education is based on emotional tendency analysis of psychological adjustment function model. Design emotional tendency analysis of music education psychological adjustment function architecture, music teaching goal as psychological adjustment function architecture building orientation, music teaching content as a foundation for psychological adjustment function architecture and music teaching process as a psychological adjustment function architecture building, music teaching evaluation as the key of building key regulating function architecture,… More >

GUSTAVO MARTÍN VILLOLDO¹, MARÍA TERESA POMBO², MARIANA ARIS³, JOAQUÍN CHEMI¹, PABLO MANDÓ³, SUPRIYA NAGARAJU⁴, JUAN CAMEAN¹, ADRIÁN BURIONI¹, DEBORAH EGEA¹, MORA AMAT⁵, JOSÉ LEÓN MELLADO³, JOSÉ MORDOH³, ALBERTO VILLARONGA¹, MARÍA MARCELA BARRIO^3,*

Oncology Research, Vol.31, No.2, pp. 207-220, 2023, DOI:10.32604/or.2023.028163

Abstract Intravesical Bacillus Calmette Guerin (BCG) is the gold standard therapy for intermediate/high-risk nonmuscle invasive bladder cancer (NMIBC). However, the response rate is ~60%, and 50% of non-responders will progress to muscle-invasive disease. BCG induces massive local infiltration of inflammatory cells (Th1) and ultimately cytotoxic tumor elimination. We searched for predictive biomarker of BCG response by analyzing tumor-infiltrating lymphocyte (TIL) polarization in the tumor microenvironment (TME) in pre-treatment biopsies. Pre-treatment biopsies from patients with NMIBC who received adequate intravesical instillation of BCG (n = 32) were evaluated retrospectively by immunohistochemistry. TME polarization was assessed by quantifying the T-Bet+ (Th1) and GATA-3+… More > Graphic Abstract

Shaista Habib¹, Aqsa Majeed¹, Muhammad Akram^2,*, Mohammed M. Ali Al-Shamiri^3,4

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.3, pp. 2873-2894, 2023, DOI:10.32604/cmes.2023.026294

Abstract The Floyd-Warshall algorithm is frequently used to determine the shortest path between any pair of nodes. It works well for crisp weights, but the problem arises when weights are vague and uncertain. Let us take an example of computer networks, where the chosen path might no longer be appropriate due to rapid changes in network conditions. The optimal path from among all possible courses is chosen in computer networks based on a variety of parameters. In this paper, we design a new variant of the Floyd-Warshall algorithm that identifies an All-Pair Shortest Path (APSP) in an uncertain situation of a… More > Graphic Abstract

Da Li, Guodong Zhang, Ke Sun^*, Shuzhan Bai, Guoxiang Li^*

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.6, pp. 1479-1493, 2023, DOI:10.32604/fdmp.2023.022634

Abstract A dedicated heat exchanger model is introduced for the optimization of heavy-duty diesel engines. The model is a prerequisite for the execution of CFD simulations, which are used to improve waste heat recovery in these systems. Several optimization methods coupled with different types of working fluids are compared in terms of exergy efficiency and heat exchanger complicity. The three considered optimization methods all lead to significant improvements in the R245fa and R1233zd systems with a comparatively low evaporation temperature. The optimal R245fa system has the highest efficiency increase (77.49%). The cyclopentane system displays the highest effi- ciency among the optimized… More >

Xiaorui Zhang^1,2,3,*, Xianglong Zeng¹, Wei Sun^3,4, Yongjun Ren^1,2,3, Tong Xu⁵

Computer Systems Science and Engineering, Vol.46, No.1, pp. 671-686, 2023, DOI:10.32604/csse.2023.035119

Abstract Gesture recognition technology enables machines to read human gestures and has significant application prospects in the fields of human-computer interaction and sign language translation. Existing researches usually use convolutional neural networks to extract features directly from raw gesture data for gesture recognition, but the networks are affected by much interference information in the input data and thus fit to some unimportant features. In this paper, we proposed a novel method for encoding spatio-temporal information, which can enhance the key features required for gesture recognition, such as shape, structure, contour, position and hand motion of gestures, thereby improving the accuracy of… More >

Gaoyuan Yu¹, Yunfeng Lou², Hang Dong³, Junjie Li¹, Xianlong Jin^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.136, No.1, pp. 135-155, 2023, DOI:10.32604/cmes.2023.025166

Abstract Heterogeneous multicore clusters are becoming more popular for high-performance computing due to their great computing power and cost-to-performance effectiveness nowadays. Nevertheless, parallel efficiency degradation is still a problem in large-scale structural analysis based on heterogeneous multicore clusters. To solve it, a hybrid hierarchical parallel algorithm (HHPA) is proposed on the basis of the conventional domain decomposition algorithm (CDDA) and the parallel sparse solver. In this new algorithm, a three-layer parallelization of the computational procedure is introduced to enable the separation of the communication of inter-nodes, heterogeneous-core-groups (HCGs) and inside-heterogeneous-core-groups through mapping computing tasks to various hardware layers. This approach can… More >

WENLI ZENG¹, FENG LING², KAINUO DANG³, QINGJIA CHI^3,*

BIOCELL, Vol.47, No.3, pp. 581-592, 2023, DOI:10.32604/biocell.2023.025957

Abstract Hepatocellular carcinoma (HCC) is associated with poor prognosis and fluctuations in immune status. Although studies have found that secreted phosphoprotein 1 (SPP1) is involved in HCC progression, its independent prognostic value and immune-mediated role remain unclear. Using The Cancer Genome Atlas and Gene Expression Omnibus data, we found that low expression of SPP1 is significantly associated with improved survival of HCC patients and that SPP1 expression is correlated with clinical characteristics. Univariate and multivariate Cox regression confirmed that SPP1 is an independent prognostic factor of HCC. Subsequently, we found that T cell CD4 memory-activated monocytes, M0 macrophages, and resting mast… More >

Yu Xiao^1,2,#, Jianping Jiang^3,#, Yan Chen^1,4, Yi Huang¹, Changyuan Wei^1,*

Oncologie, Vol.24, No.4, pp. 729-742, 2022, DOI:10.32604/oncologie.2022.026118

Abstract Background: Immunotherapy is becoming a powerful approach in the treatment of breast cancer. However, high response rates in the majority of breast cancer patients have yet to be achieved. Materials and Methods: Based on public data sources, we identified 22 genes that are correlated with PD-1 expression as well as differentially expressed between tumor tissues and normal tissues, and high expression of all the key genes was correlated with a superior survival outcome. Using the least absolute shrinkage and selection operator Cox regression model, a risk score was constructed. Results: A multivariate Cox analysis showed that the constructed risk score… More >