Han Yu1, Tal Geva2, Rahul H. Rathod2, Alexander Tang2, Chun Yang3, Zheyang Wu3, Kristen L. Billiar4, Xueying Huang5, Dalin Tang1,*,3
Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 56-57, 2019, DOI:10.32604/mcb.2019.07257
Abstract Computational biomechanical models are widely used in cardiovascular research for better understanding of mechanisms governing disease development, quantitative diagnostic strategies and improved surgical designs with better outcome. Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle (RV) failure. The current surgical approach, which includes pulmonary valve replacement/insertion (PVR), has yielded mixed results. An innovative PVR surgical approach was proposed using active contracting bands to help ventricle to contract and improve RV function measured by ejection fraction [1]. Muscle active contraction caused by sarcomere shortening leads to… More >
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