Timur Mese1, Baris Guven2, Murat Muhtar Yilmazer1, Cem Karadeniz3, Rahmi Ozdemir1, Onder Doksoz1
Congenital Heart Disease, Vol.13, No.4, pp. 506-511, 2018, DOI:10.1111/chd.12616
Abstract Background: Mean platelet volume (MPV), platecrit, and platelet distribution width (PDW) are
markers of platelet activation. Previous studies have found that platelet activation occurs in
patients with pulmonary arterial hypertension. Platelet indices including MPV, PDW, and platecrit
have not been studied in children with congenital heart disease associated pulmonary arterial
hypertension (APAH-CHD) who survived and those who died.
Objective: The objective of this study to investigate the value of platelet indices with clinical and
hemodynamic indicators predicting the disease severity and survival in children with APAH-CHD.
Methods: This was a nested case-control study. MPV, platecrit, and PDW levels… More >
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