Rohit S. Loomba1, Seth B. Gray2, Saul Flores3
Congenital Heart Disease, Vol.13, No.5, pp. 646-654, 2018, DOI:10.1111/chd.12662
Abstract Introduction: Ketamine is a drug often used for procedural sedation or as adjunct
agent for general sedation in children with congenital heart disease. In the clinical
realm, there is often confusion regarding the effects of ketamine on hemodynamics,
particularly pulmonary vascular resistance and systemic vascular resistance. We per‐
formed a meta‐analysis of studies investigating the effects of ketamine on
hemodynamics.
Methods: A systematic review was conducted to identify studies characterizing the
hemodynamic effects of ketamine in children with congenital heart disease. Studies
were assessed for quality and those of satisfactory quality with pre‐ and postketa‐
mine hemodynamics… More >
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