Jim T. Vehmeijer1, Zeliha Koyak1, A. Suzanne Vink1, Werner Budts2,3, Louise Harris4, Candice K. Silversides4, Erwin N. Oechslin4, Aeilko H. Zwinderman5, Barbara J.M. Mulder1,6, Joris R. de Groot1
Congenital Heart Disease, Vol.14, No.6, pp. 952-957, 2019, DOI:10.1111/chd.12847
Abstract Objective: Adult congenital heart disease (ACHD) patients are at risk of sudden
cardiac death (SCD). However, methods for risk stratification are not yet well‐
defined. The Tpeak‐Tend (TpTe) interval, a measure of dispersion of ventricular repolari‐
zation, is a risk factor for SCD in non‐ACHD patients. We aim to evaluate whether
TpTe can be used in risk stratification for SCD in ACHD patients.
Design: From an international multicenter cohort of 25 790 ACHD patients, we iden‐
tified all SCD cases. Cases were matched to controls by age, gender, congenital de‐
fect, and (surgical) intervention.
Outcome Measures: TpTe was measured… More >
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